PDB: 6VNC — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 6VNCA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 6VNCA O60674 840 1131 1132.0 R6V:61201 Type1 Inactive DFGin 6.1747 13.1783 ABAminus -125.0, 1.92 -144.44, 138.94 -134.55, 26.62 299.16, 82.3 -63.96, -13.53 in-in in 8.7325 Saltbr-in 3.2308 HRD-in -71.26, -46.55 70.57, -1.02 in-in-in SNCiii in-in ActLoopNT-in 2.7532 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -96.44, 156.2 APE9-dihe-in -132.4, 123.78 APE8-dihe-in -79.65, 76.35 APE8-rot-na 29.35 APE67-dihe-in -79.45, -6.71 -61.99, -27.52 APE12-dist-na 12.877 APE11-dist-na 8.4863 APE10-dist-na 9.1162 APE9-dist-in 6.8519 None PTR1007 PTR1007 XRAY 2.3 0.227 0.269 A 308.0 292.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 6vnc TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNCB O60674 843 1131 1132.0 R6V:61201 Type1 Inactive DFGin 6.154 13.1702 ABAminus -122.12, 1.77 -145.07, 140.87 -135.43, 27.24 299.55, 83.32 -63.99, -17.1 in-in in 8.8707 Saltbr-in 2.9219 HRD-in -71.34, -45.2 70.18, -2.12 in-in-in SNCiii in-in ActLoopNT-in 2.7507 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -112.37, 171.08 APE9-dihe-in -127.34, 149.39 APE8-dihe-in -72.05, 74.05 APE8-rot-na 32.11 APE67-dihe-in -79.07, -5.61 -65.16, -22.9 APE12-dist-na 12.8084 APE11-dist-na 12.8213 APE10-dist-na 13.9136 APE9-dist-in 7.9337 None PTR1007 PTR1007 XRAY 2.3 0.227 0.269 B 308.0 289.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 6vnc TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 6VNC — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 6VNCA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 6VNCA O60674 840 1131 1132.0 R6V:61201 Type1 Inactive DFGin 6.1747 13.1783 ABAminus -125.0, 1.92 -144.44, 138.94 -134.55, 26.62 299.16, 82.3 -63.96, -13.53 in-in in 8.7325 Saltbr-in 3.2308 HRD-in -71.26, -46.55 70.57, -1.02 in-in-in SNCiii in-in ActLoopNT-in 2.7532 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -96.44, 156.2 APE9-dihe-in -132.4, 123.78 APE8-dihe-in -79.65, 76.35 APE8-rot-na 29.35 APE67-dihe-in -79.45, -6.71 -61.99, -27.52 APE12-dist-na 12.877 APE11-dist-na 8.4863 APE10-dist-na 9.1162 APE9-dist-in 6.8519 None PTR1007 PTR1007 XRAY 2.3 0.227 0.269 A 308.0 292.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 6vnc Homo sapiens TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNCB O60674 843 1131 1132.0 R6V:61201 Type1 Inactive DFGin 6.154 13.1702 ABAminus -122.12, 1.77 -145.07, 140.87 -135.43, 27.24 299.55, 83.32 -63.99, -17.1 in-in in 8.8707 Saltbr-in 2.9219 HRD-in -71.34, -45.2 70.18, -2.12 in-in-in SNCiii in-in ActLoopNT-in 2.7507 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -112.37, 171.08 APE9-dihe-in -127.34, 149.39 APE8-dihe-in -72.05, 74.05 APE8-rot-na 32.11 APE67-dihe-in -79.07, -5.61 -65.16, -22.9 APE12-dist-na 12.8084 APE11-dist-na 12.8213 APE10-dist-na 13.9136 APE9-dist-in 7.9337 None PTR1007 PTR1007 XRAY 2.3 0.227 0.269 B 308.0 289.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 6vnc Homo sapiens TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 6VNC — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name