PDB: 6VN8 — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 6VN8A
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 6VN8A O60674 840 1132 1132.0 3JW:61201 Type1 Inactive DFGin 6.42 13.799 ABAminus -116.88, -11.5 -143.58, 137.54 -129.5, 26.21 292.83, 83.89 -62.24, -22.44 in-in in 8.581 Saltbr-in 2.751 HRD-in -74.45, -48.89 74.52, -4.46 in-in-in SNCiii in-in ActLoopNT-in 2.788 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -87.86, 136.24 APE9-dihe-in -126.34, 122.3 APE8-dihe-in -79.17, 73.44 APE8-rot-na 30.57 APE67-dihe-in -82.31, 0.54 -60.95, -23.7 APE12-dist-na 13.292 APE11-dist-na 9.326 APE10-dist-na 8.777 APE9-dist-in 6.956 None PTR1007 PTR1007 XRAY 1.9 0.185 0.215 A 308 293 0 0 0 0 [[545, 807], [849, 1125]] 2.0 6vn8 TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1 260 260 993 994 995 997 999 882 898 902 973 975 974 976 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VN8B O60674 843 1131 1132.0 3JW:61201 Type1 Inactive DFGin 6.202 13.633 ABAminus -114.34, -11.39 -144.21, 140.62 -131.03, 26.72 294.72, 85.25 -60.7, -25.73 in-in in 8.616 Saltbr-in 2.632 HRD-in -74.15, -47.61 71.7, -1.3 in-in-in SNCiii in-in ActLoopNT-in 2.769 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -77.46, 140.77 APE9-dihe-in -119.45, 142.72 APE8-dihe-in -71.39, 69.25 APE8-rot-na 31.65 APE67-dihe-in -81.85, -1.4 -64.46, -21.62 APE12-dist-na 13.405 APE11-dist-na 12.858 APE10-dist-na 13.328 APE9-dist-in 7.896 None PTR1007 PTR1007 XRAY 1.9 0.185 0.215 B 308 289 0 0 0 0 [[545, 807], [849, 1125]] 2.0 6vn8 TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1 260 260 993 994 995 997 999 882 898 902 973 975 974 976 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 6VN8 — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 6VN8A
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 6VN8A O60674 840 1132 1132.0 3JW:61201 Type1 Inactive DFGin 6.42 13.799 ABAminus -116.88, -11.5 -143.58, 137.54 -129.5, 26.21 292.83, 83.89 -62.24, -22.44 in-in in 8.581 Saltbr-in 2.751 HRD-in -74.45, -48.89 74.52, -4.46 in-in-in SNCiii in-in ActLoopNT-in 2.788 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -87.86, 136.24 APE9-dihe-in -126.34, 122.3 APE8-dihe-in -79.17, 73.44 APE8-rot-na 30.57 APE67-dihe-in -82.31, 0.54 -60.95, -23.7 APE12-dist-na 13.292 APE11-dist-na 9.326 APE10-dist-na 8.777 APE9-dist-in 6.956 None PTR1007 PTR1007 XRAY 1.9 0.185 0.215 A 308 293 0 0 0 0 [[545, 807], [849, 1125]] 2.0 6vn8 Homo sapiens TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1 260 260 993 994 995 997 999 882 898 902 973 975 974 976 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VN8B O60674 843 1131 1132.0 3JW:61201 Type1 Inactive DFGin 6.202 13.633 ABAminus -114.34, -11.39 -144.21, 140.62 -131.03, 26.72 294.72, 85.25 -60.7, -25.73 in-in in 8.616 Saltbr-in 2.632 HRD-in -74.15, -47.61 71.7, -1.3 in-in-in SNCiii in-in ActLoopNT-in 2.769 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -77.46, 140.77 APE9-dihe-in -119.45, 142.72 APE8-dihe-in -71.39, 69.25 APE8-rot-na 31.65 APE67-dihe-in -81.85, -1.4 -64.46, -21.62 APE12-dist-na 13.405 APE11-dist-na 12.858 APE10-dist-na 13.328 APE9-dist-in 7.896 None PTR1007 PTR1007 XRAY 1.9 0.185 0.215 B 308 289 0 0 0 0 [[545, 807], [849, 1125]] 2.0 6vn8 Homo sapiens TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1 260 260 993 994 995 997 999 882 898 902 973 975 974 976 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 6VN8 — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name