PDB: 6VGL — TYR JAK2_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 4 100.0% 6VGLA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 6VGLA O60674 840 1132 1132.0 RXT:61201 Type1 Inactive DFGin 6.446 13.513 ABAminus -117.0, -7.21 -146.07, 141.05 -130.49, 28.54 292.94, 81.12 -65.56, -22.11 in-in in 8.428 Saltbr-in 2.754 HRD-in -71.73, -48.4 73.96, -1.64 in-in-in SNCiii in-in ActLoopNT-in 2.781 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -88.11, 129.62 APE9-dihe-in -121.72, 122.37 APE8-dihe-in -84.02, 76.32 APE8-rot-na 33.09 APE67-dihe-in -78.28, -3.75 -61.51, -29.27 APE12-dist-na 13.555 APE11-dist-na 9.49 APE10-dist-na 8.47 APE9-dist-in 7.051 None PTR1007 PTR1007 XRAY 1.9 0.182 0.217 A 308 293 0 0 0 0 [[545, 807], [849, 1125]] 2.0 6vgl TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1 260 260 993 994 995 997 999 882 898 902 973 975 974 976 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VGLB O60674 840 1132 1132.0 RXT:61201 Type1 Inactive DFGin 6.445 13.616 ABAminus -116.85, -7.44 -149.05, 140.79 -130.84, 27.89 290.32, 82.4 -67.42, -21.82 in-in in 8.398 Saltbr-in 2.781 HRD-in -71.23, -46.75 71.83, -3.65 in-in-in SNCiii in-in ActLoopNT-in 2.815 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -93.23, 146.01 APE9-dihe-in -126.07, 123.7 APE8-dihe-in -81.61, 74.86 APE8-rot-na 31.65 APE67-dihe-in -77.61, -3.9 -60.75, -30.09 APE12-dist-na 13.288 APE11-dist-na 9.377 APE10-dist-na 8.665 APE9-dist-in 6.981 None PTR1007 PTR1007 XRAY 1.9 0.182 0.217 B 308 293 0 0 0 0 [[545, 807], [849, 1125]] 2.0 6vgl TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1 260 260 993 994 995 997 999 882 898 902 973 975 974 976 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VGLC O60674 843 1131 1132.0 RXT:61201 Type1 Inactive DFGin 6.222 13.379 ABAminus -115.55, -9.12 -143.9, 140.61 -132.23, 26.54 293.7, 85.16 -65.11, -21.72 in-in in 8.417 Saltbr-in 2.704 HRD-in -73.34, -48.11 71.88, -3.21 in-in-in SNCiii in-in ActLoopNT-in 2.813 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -85.66, 127.53 APE9-dihe-in -113.0, 141.05 APE8-dihe-in -75.8, 72.0 APE8-rot-na 32.54 APE67-dihe-in -77.35, -4.0 -61.49, -27.59 APE12-dist-na 13.338 APE11-dist-na 13.082 APE10-dist-na 13.222 APE9-dist-in 7.904 None PTR1007 PTR1007 XRAY 1.9 0.182 0.217 C 308 289 0 0 0 0 [[545, 807], [849, 1125]] 2.0 6vgl TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1 260 260 993 994 995 997 999 882 898 902 973 975 974 976 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VGLD O60674 843 1131 1132.0 RXT:61201 Type1 Inactive DFGin 6.288 13.488 ABAminus -116.23, -6.92 -148.77, 141.37 -133.22, 26.24 295.62, 83.68 -64.72, -19.37 in-in in 8.434 Saltbr-in 2.677 HRD-in -70.05, -46.57 72.2, -0.79 in-in-in SNCiii in-in ActLoopNT-in 2.763 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -82.83, 129.61 APE9-dihe-in -113.86, 144.08 APE8-dihe-in -77.54, 74.01 APE8-rot-na 34.3 APE67-dihe-in -79.99, -2.4 -62.52, -26.5 APE12-dist-na 13.31 APE11-dist-na 13.261 APE10-dist-na 13.273 APE9-dist-in 7.82 None PTR1007 PTR1007 XRAY 1.9 0.182 0.217 D 308 289 0 0 0 0 [[545, 807], [849, 1125]] 2.0 6vgl TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1 260 260 993 994 995 997 999 882 898 902 973 975 974 976 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 6VGL — TYR JAK2_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 4 100.0% 6VGLA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 6VGLA O60674 840 1132 1132.0 RXT:61201 Type1 Inactive DFGin 6.446 13.513 ABAminus -117.0, -7.21 -146.07, 141.05 -130.49, 28.54 292.94, 81.12 -65.56, -22.11 in-in in 8.428 Saltbr-in 2.754 HRD-in -71.73, -48.4 73.96, -1.64 in-in-in SNCiii in-in ActLoopNT-in 2.781 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -88.11, 129.62 APE9-dihe-in -121.72, 122.37 APE8-dihe-in -84.02, 76.32 APE8-rot-na 33.09 APE67-dihe-in -78.28, -3.75 -61.51, -29.27 APE12-dist-na 13.555 APE11-dist-na 9.49 APE10-dist-na 8.47 APE9-dist-in 7.051 None PTR1007 PTR1007 XRAY 1.9 0.182 0.217 A 308 293 0 0 0 0 [[545, 807], [849, 1125]] 2.0 6vgl Homo sapiens TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1 260 260 993 994 995 997 999 882 898 902 973 975 974 976 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VGLB O60674 840 1132 1132.0 RXT:61201 Type1 Inactive DFGin 6.445 13.616 ABAminus -116.85, -7.44 -149.05, 140.79 -130.84, 27.89 290.32, 82.4 -67.42, -21.82 in-in in 8.398 Saltbr-in 2.781 HRD-in -71.23, -46.75 71.83, -3.65 in-in-in SNCiii in-in ActLoopNT-in 2.815 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -93.23, 146.01 APE9-dihe-in -126.07, 123.7 APE8-dihe-in -81.61, 74.86 APE8-rot-na 31.65 APE67-dihe-in -77.61, -3.9 -60.75, -30.09 APE12-dist-na 13.288 APE11-dist-na 9.377 APE10-dist-na 8.665 APE9-dist-in 6.981 None PTR1007 PTR1007 XRAY 1.9 0.182 0.217 B 308 293 0 0 0 0 [[545, 807], [849, 1125]] 2.0 6vgl Homo sapiens TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1 260 260 993 994 995 997 999 882 898 902 973 975 974 976 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VGLC O60674 843 1131 1132.0 RXT:61201 Type1 Inactive DFGin 6.222 13.379 ABAminus -115.55, -9.12 -143.9, 140.61 -132.23, 26.54 293.7, 85.16 -65.11, -21.72 in-in in 8.417 Saltbr-in 2.704 HRD-in -73.34, -48.11 71.88, -3.21 in-in-in SNCiii in-in ActLoopNT-in 2.813 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -85.66, 127.53 APE9-dihe-in -113.0, 141.05 APE8-dihe-in -75.8, 72.0 APE8-rot-na 32.54 APE67-dihe-in -77.35, -4.0 -61.49, -27.59 APE12-dist-na 13.338 APE11-dist-na 13.082 APE10-dist-na 13.222 APE9-dist-in 7.904 None PTR1007 PTR1007 XRAY 1.9 0.182 0.217 C 308 289 0 0 0 0 [[545, 807], [849, 1125]] 2.0 6vgl Homo sapiens TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1 260 260 993 994 995 997 999 882 898 902 973 975 974 976 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VGLD O60674 843 1131 1132.0 RXT:61201 Type1 Inactive DFGin 6.288 13.488 ABAminus -116.23, -6.92 -148.77, 141.37 -133.22, 26.24 295.62, 83.68 -64.72, -19.37 in-in in 8.434 Saltbr-in 2.677 HRD-in -70.05, -46.57 72.2, -0.79 in-in-in SNCiii in-in ActLoopNT-in 2.763 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -82.83, 129.61 APE9-dihe-in -113.86, 144.08 APE8-dihe-in -77.54, 74.01 APE8-rot-na 34.3 APE67-dihe-in -79.99, -2.4 -62.52, -26.5 APE12-dist-na 13.31 APE11-dist-na 13.261 APE10-dist-na 13.273 APE9-dist-in 7.82 None PTR1007 PTR1007 XRAY 1.9 0.182 0.217 D 308 289 0 0 0 0 [[545, 807], [849, 1125]] 2.0 6vgl Homo sapiens TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1 260 260 993 994 995 997 999 882 898 902 973 975 974 976 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 6VGL — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name