PDB: 6V6Q — TYR FGFR2_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 75.0% 6V6QB
DFGin BLBminus 1 25.0% 6V6QC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR2 FGFR2_HUMAN 6V6QA P21802 466 765 821.0 ACP:901 ATPlike Inactive DFGin 6.8945 13.9075 BLAminus -137.26, -178.98 59.51, 71.9 -86.77, 13.5 292.04, 83.56 -59.04, -31.29 in-in in 7.2461 Saltbr-in 3.2891 HRD-in -72.64, -45.97 77.04, -16.81 in-in-out SNCiio in-out ActLoopNT-in 2.9278 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -110.45, 33.95 APE9-dihe-in -111.95, 129.79 APE8-dihe-in -53.65, 121.81 APE8-rot-na 327.05 APE67-dihe-in -70.56, -11.31 -58.83, -38.12 APE12-dist-na 14.2635 APE11-dist-na 10.4899 APE10-dist-na 7.7703 APE9-dist-in 5.206 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F PTR656 PTR656 XRAY 2.46 0.213 0.239 A 411.0 286.0 14 30 30 0 [[481, 759]] 1.0 6v6q TYR_FGFR2_HUMAN TYR 8.7e-101 342.6 1.0 260.0 260.0 643 644 645 647 649 517 534 538 623 625 624 626.0 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6V6QB P21802 467 766 821.0 ACP:901 ATPlike Inactive DFGin 6.8092 14.1253 BLAminus -136.61, -177.61 60.52, 69.31 -88.63, 15.47 290.7, 96.84 -63.12, -28.34 in-in in 7.3426 Saltbr-in 3.2951 HRD-in -73.07, -46.4 74.87, -14.44 in-in-out SNCiio in-out ActLoopNT-in 2.9198 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -116.84, 37.71 APE9-dihe-in -109.58, 130.31 APE8-dihe-in -50.87, 122.1 APE8-rot-na 324.14 APE67-dihe-in -69.97, -12.27 -61.49, -37.1 APE12-dist-na 14.1352 APE11-dist-na 10.5874 APE10-dist-na 8.0645 APE9-dist-in 5.1521 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F PTR656 PTR656 XRAY 2.46 0.213 0.239 B 411.0 291.0 9 30 30 0 [[481, 759]] 1.0 6v6q TYR_FGFR2_HUMAN TYR 8.7e-101 342.6 1.0 260.0 260.0 643 644 645 647 649 517 534 538 623 625 624 626.0 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6V6QD P21802 467 765 821.0 ACP:901 ATPlike Inactive DFGin 6.9358 13.9889 BLAminus -136.56, -179.05 59.21, 72.83 -88.1, 16.16 292.51, 97.85 -58.15, -33.51 in-in in 7.3798 Saltbr-in 3.3337 HRD-in -71.81, -47.08 75.08, -13.84 in-in-out SNCiio in-out ActLoopNT-in 2.9416 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -115.25, 35.34 APE9-dihe-in -111.85, 128.58 APE8-dihe-in -53.13, 121.4 APE8-rot-na 327.69 APE67-dihe-in -69.26, -12.5 -60.26, -36.04 APE12-dist-na 999.0 APE11-dist-na 10.1403 APE10-dist-na 7.4327 APE9-dist-in 5.1119 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F PTR656 PTR656 XRAY 2.46 0.213 0.239 D 411.0 276.0 23 30 21 9 [[481, 759]] 1.0 6v6q TYR_FGFR2_HUMAN TYR 8.7e-101 342.6 1.0 260.0 260.0 643 644 645 647 649 517 534 538 623 625 624 626.0 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6V6QC P21802 467 766 821.0 ACP:901 ATPlike Inactive DFGin 6.7663 13.6427 BLBminus -136.89, -177.89 59.28, 74.24 -85.91, -161.66 300.29, 95.93 81.23, -12.62 in-in in 7.4635 Saltbr-in 3.3138 HRD-in -72.01, -47.4 74.74, -13.46 in-in-out SNCiio in-out ActLoopNT-in 2.9412 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -111.47, 28.67 APE9-dihe-in -111.04, 128.94 APE8-dihe-in -52.92, 121.96 APE8-rot-na 327.46 APE67-dihe-in -69.24, -12.82 -58.84, -37.31 APE12-dist-na 999.0 APE11-dist-na 10.4975 APE10-dist-na 7.4308 APE9-dist-in 5.0885 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F PTR656 PTR656 XRAY 2.46 0.213 0.239 C 411.0 279.0 21 30 19 11 [[481, 759]] 1.0 6v6q TYR_FGFR2_HUMAN TYR 8.7e-101 342.6 1.0 260.0 260.0 643 644 645 647 649 517 534 538 623 625 624 626.0 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2

PDB: 6V6Q — TYR FGFR2_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 75.0% 6V6QB
DFGin BLBminus 1 25.0% 6V6QC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR2 FGFR2_HUMAN 6V6QA P21802 466 765 821.0 ACP:901 ATPlike Inactive DFGin 6.8945 13.9075 BLAminus -137.26, -178.98 59.51, 71.9 -86.77, 13.5 292.04, 83.56 -59.04, -31.29 in-in in 7.2461 Saltbr-in 3.2891 HRD-in -72.64, -45.97 77.04, -16.81 in-in-out SNCiio in-out ActLoopNT-in 2.9278 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -110.45, 33.95 APE9-dihe-in -111.95, 129.79 APE8-dihe-in -53.65, 121.81 APE8-rot-na 327.05 APE67-dihe-in -70.56, -11.31 -58.83, -38.12 APE12-dist-na 14.2635 APE11-dist-na 10.4899 APE10-dist-na 7.7703 APE9-dist-in 5.206 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F PTR656 PTR656 XRAY 2.46 0.213 0.239 A 411.0 286.0 14 30 30 0 [[481, 759]] 1.0 6v6q Homo sapiens TYR_FGFR2_HUMAN TYR 8.7e-101 342.6 1.0 260.0 260.0 643 644 645 647 649 517 534 538 623 625 624 626.0 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6V6QB P21802 467 766 821.0 ACP:901 ATPlike Inactive DFGin 6.8092 14.1253 BLAminus -136.61, -177.61 60.52, 69.31 -88.63, 15.47 290.7, 96.84 -63.12, -28.34 in-in in 7.3426 Saltbr-in 3.2951 HRD-in -73.07, -46.4 74.87, -14.44 in-in-out SNCiio in-out ActLoopNT-in 2.9198 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -116.84, 37.71 APE9-dihe-in -109.58, 130.31 APE8-dihe-in -50.87, 122.1 APE8-rot-na 324.14 APE67-dihe-in -69.97, -12.27 -61.49, -37.1 APE12-dist-na 14.1352 APE11-dist-na 10.5874 APE10-dist-na 8.0645 APE9-dist-in 5.1521 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F PTR656 PTR656 XRAY 2.46 0.213 0.239 B 411.0 291.0 9 30 30 0 [[481, 759]] 1.0 6v6q Homo sapiens TYR_FGFR2_HUMAN TYR 8.7e-101 342.6 1.0 260.0 260.0 643 644 645 647 649 517 534 538 623 625 624 626.0 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6V6QD P21802 467 765 821.0 ACP:901 ATPlike Inactive DFGin 6.9358 13.9889 BLAminus -136.56, -179.05 59.21, 72.83 -88.1, 16.16 292.51, 97.85 -58.15, -33.51 in-in in 7.3798 Saltbr-in 3.3337 HRD-in -71.81, -47.08 75.08, -13.84 in-in-out SNCiio in-out ActLoopNT-in 2.9416 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -115.25, 35.34 APE9-dihe-in -111.85, 128.58 APE8-dihe-in -53.13, 121.4 APE8-rot-na 327.69 APE67-dihe-in -69.26, -12.5 -60.26, -36.04 APE12-dist-na 999.0 APE11-dist-na 10.1403 APE10-dist-na 7.4327 APE9-dist-in 5.1119 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F PTR656 PTR656 XRAY 2.46 0.213 0.239 D 411.0 276.0 23 30 21 9 [[481, 759]] 1.0 6v6q Homo sapiens TYR_FGFR2_HUMAN TYR 8.7e-101 342.6 1.0 260.0 260.0 643 644 645 647 649 517 534 538 623 625 624 626.0 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6V6QC P21802 467 766 821.0 ACP:901 ATPlike Inactive DFGin 6.7663 13.6427 BLBminus -136.89, -177.89 59.28, 74.24 -85.91, -161.66 300.29, 95.93 81.23, -12.62 in-in in 7.4635 Saltbr-in 3.3138 HRD-in -72.01, -47.4 74.74, -13.46 in-in-out SNCiio in-out ActLoopNT-in 2.9412 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -111.47, 28.67 APE9-dihe-in -111.04, 128.94 APE8-dihe-in -52.92, 121.96 APE8-rot-na 327.46 APE67-dihe-in -69.24, -12.82 -58.84, -37.31 APE12-dist-na 999.0 APE11-dist-na 10.4975 APE10-dist-na 7.4308 APE9-dist-in 5.0885 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F PTR656 PTR656 XRAY 2.46 0.213 0.239 C 411.0 279.0 21 30 19 11 [[481, 759]] 1.0 6v6q Homo sapiens TYR_FGFR2_HUMAN TYR 8.7e-101 342.6 1.0 260.0 260.0 643 644 645 647 649 517 534 538 623 625 624 626.0 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2

PDB: 6V6Q — TYR FGFR2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name