PDB: 6V6Q — TYR FGFR2_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 75.0% 6V6QB
DFGin BLBminus 1 25.0% 6V6QC
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR2 FGFR2_HUMAN 6V6QA P21802 466 765 821.0 ACP:901 ATPlike Inactive DFGin 6.894 13.908 BLAminus -137.26, -178.98 59.51, 71.9 -86.77, 13.5 292.04, 83.56 -59.04, -31.29 in-in in 7.246 Saltbr-in 3.289 HRD-in -72.64, -45.97 77.04, -16.81 in-in-out SNCiio in-out ActLoopNT-in 2.928 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -110.45, 33.95 APE9-dihe-in -111.95, 129.79 APE8-dihe-in -53.65, 121.81 APE8-rot-na 327.05 APE67-dihe-in -70.56, -11.31 -58.83, -38.12 APE12-dist-na 14.264 APE11-dist-na 10.49 APE10-dist-na 7.77 APE9-dist-in 5.206 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F PTR656 PTR656 XRAY 2.46 0.213 0.239 A 411 286 14 0 0 0 [[481, 759]] 1.0 6v6q TYR_FGFR2_HUMAN TYR 8.7e-101 342.6 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6V6QB P21802 467 766 821.0 ACP:901 ATPlike Inactive DFGin 6.809 14.125 BLAminus -136.61, -177.61 60.52, 69.31 -88.63, 15.47 290.7, 96.84 -63.12, -28.34 in-in in 7.343 Saltbr-in 3.295 HRD-in -73.07, -46.4 74.87, -14.44 in-in-out SNCiio in-out ActLoopNT-in 2.92 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -116.84, 37.71 APE9-dihe-in -109.58, 130.31 APE8-dihe-in -50.87, 122.1 APE8-rot-na 324.14 APE67-dihe-in -69.97, -12.27 -61.49, -37.1 APE12-dist-na 14.135 APE11-dist-na 10.587 APE10-dist-na 8.065 APE9-dist-in 5.152 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F PTR656 PTR656 XRAY 2.46 0.213 0.239 B 411 291 9 0 0 0 [[481, 759]] 1.0 6v6q TYR_FGFR2_HUMAN TYR 8.7e-101 342.6 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6V6QD P21802 467 765 821.0 ACP:901 ATPlike Inactive DFGin 6.936 13.989 BLAminus -136.56, -179.05 59.21, 72.83 -88.1, 16.16 292.51, 97.85 -58.15, -33.51 in-in in 7.38 Saltbr-in 3.334 HRD-in -71.81, -47.08 75.08, -13.84 in-in-out SNCiio in-out ActLoopNT-in 2.942 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -115.25, 35.34 APE9-dihe-in -111.85, 128.58 APE8-dihe-in -53.13, 121.4 APE8-rot-na 327.69 APE67-dihe-in -69.26, -12.5 -60.26, -36.04 APE12-dist-na 999.0 APE11-dist-na 10.14 APE10-dist-na 7.433 APE9-dist-in 5.112 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F PTR656 PTR656 XRAY 2.46 0.213 0.239 D 411 276 23 0 0 9 [[481, 759]] 1.0 6v6q TYR_FGFR2_HUMAN TYR 8.7e-101 342.6 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6V6QC P21802 467 766 821.0 ACP:901 ATPlike Inactive DFGin 6.766 13.643 BLBminus -136.89, -177.89 59.28, 74.24 -85.91, -161.66 300.29, 95.93 81.23, -12.62 in-in in 7.463 Saltbr-in 3.314 HRD-in -72.01, -47.4 74.74, -13.46 in-in-out SNCiio in-out ActLoopNT-in 2.941 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -111.47, 28.67 APE9-dihe-in -111.04, 128.94 APE8-dihe-in -52.92, 121.96 APE8-rot-na 327.46 APE67-dihe-in -69.24, -12.82 -58.84, -37.31 APE12-dist-na 999.0 APE11-dist-na 10.498 APE10-dist-na 7.431 APE9-dist-in 5.088 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F PTR656 PTR656 XRAY 2.46 0.213 0.239 C 411 279 21 0 0 11 [[481, 759]] 1.0 6v6q TYR_FGFR2_HUMAN TYR 8.7e-101 342.6 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2

PDB: 6V6Q — TYR FGFR2_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 75.0% 6V6QB
DFGin BLBminus 1 25.0% 6V6QC
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR2 FGFR2_HUMAN 6V6QA P21802 466 765 821.0 ACP:901 ATPlike Inactive DFGin 6.894 13.908 BLAminus -137.26, -178.98 59.51, 71.9 -86.77, 13.5 292.04, 83.56 -59.04, -31.29 in-in in 7.246 Saltbr-in 3.289 HRD-in -72.64, -45.97 77.04, -16.81 in-in-out SNCiio in-out ActLoopNT-in 2.928 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -110.45, 33.95 APE9-dihe-in -111.95, 129.79 APE8-dihe-in -53.65, 121.81 APE8-rot-na 327.05 APE67-dihe-in -70.56, -11.31 -58.83, -38.12 APE12-dist-na 14.264 APE11-dist-na 10.49 APE10-dist-na 7.77 APE9-dist-in 5.206 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F PTR656 PTR656 XRAY 2.46 0.213 0.239 A 411 286 14 0 0 0 [[481, 759]] 1.0 6v6q Homo sapiens TYR_FGFR2_HUMAN TYR 8.7e-101 342.6 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6V6QB P21802 467 766 821.0 ACP:901 ATPlike Inactive DFGin 6.809 14.125 BLAminus -136.61, -177.61 60.52, 69.31 -88.63, 15.47 290.7, 96.84 -63.12, -28.34 in-in in 7.343 Saltbr-in 3.295 HRD-in -73.07, -46.4 74.87, -14.44 in-in-out SNCiio in-out ActLoopNT-in 2.92 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -116.84, 37.71 APE9-dihe-in -109.58, 130.31 APE8-dihe-in -50.87, 122.1 APE8-rot-na 324.14 APE67-dihe-in -69.97, -12.27 -61.49, -37.1 APE12-dist-na 14.135 APE11-dist-na 10.587 APE10-dist-na 8.065 APE9-dist-in 5.152 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F PTR656 PTR656 XRAY 2.46 0.213 0.239 B 411 291 9 0 0 0 [[481, 759]] 1.0 6v6q Homo sapiens TYR_FGFR2_HUMAN TYR 8.7e-101 342.6 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6V6QD P21802 467 765 821.0 ACP:901 ATPlike Inactive DFGin 6.936 13.989 BLAminus -136.56, -179.05 59.21, 72.83 -88.1, 16.16 292.51, 97.85 -58.15, -33.51 in-in in 7.38 Saltbr-in 3.334 HRD-in -71.81, -47.08 75.08, -13.84 in-in-out SNCiio in-out ActLoopNT-in 2.942 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -115.25, 35.34 APE9-dihe-in -111.85, 128.58 APE8-dihe-in -53.13, 121.4 APE8-rot-na 327.69 APE67-dihe-in -69.26, -12.5 -60.26, -36.04 APE12-dist-na 999.0 APE11-dist-na 10.14 APE10-dist-na 7.433 APE9-dist-in 5.112 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F PTR656 PTR656 XRAY 2.46 0.213 0.239 D 411 276 23 0 0 9 [[481, 759]] 1.0 6v6q Homo sapiens TYR_FGFR2_HUMAN TYR 8.7e-101 342.6 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6V6QC P21802 467 766 821.0 ACP:901 ATPlike Inactive DFGin 6.766 13.643 BLBminus -136.89, -177.89 59.28, 74.24 -85.91, -161.66 300.29, 95.93 81.23, -12.62 in-in in 7.463 Saltbr-in 3.314 HRD-in -72.01, -47.4 74.74, -13.46 in-in-out SNCiio in-out ActLoopNT-in 2.941 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -111.47, 28.67 APE9-dihe-in -111.04, 128.94 APE8-dihe-in -52.92, 121.96 APE8-rot-na 327.46 APE67-dihe-in -69.24, -12.82 -58.84, -37.31 APE12-dist-na 999.0 APE11-dist-na 10.498 APE10-dist-na 7.431 APE9-dist-in 5.088 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F PTR656 PTR656 XRAY 2.46 0.213 0.239 C 411 279 21 0 0 11 [[481, 759]] 1.0 6v6q Homo sapiens TYR_FGFR2_HUMAN TYR 8.7e-101 342.6 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2

PDB: 6V6Q — TYR FGFR2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name