PDB: 6V66 — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 3 75.0% 6V66A
DFGin BLBplus 1 25.0% 6V66D
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 6V66D P00533 701 1014 1210.0 QP1:1203 Type1 Inactive DFGin 4.096 13.943 BLBplus -133.25, 173.78 71.02, 17.1 -71.48, 143.37 58.07, 94.52 76.41, -7.86 out-out out 14.093 Saltbr-out 14.181 HRD-in -71.49, -55.9 81.36, -15.85 out-out-out SNCooo out-out ActLoopNT-out 6.527 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -93.31, -7.02 APE9-dihe-in -100.17, 123.42 APE8-dihe-in -79.15, 63.8 APE8-rot-na 32.12 APE67-dihe-in -77.89, -1.58 -50.41, -43.42 APE12-dist-na 18.544 APE11-dist-na 16.043 APE10-dist-na 11.737 APE9-dist-in 7.947 T790M,V948R None None XRAY 1.79 0.187 0.226 D 327 314 0 0 0 0 [[712, 970]] 1.0 6v66 TYR_EGFR_HUMAN TYR 6e-88 300.6 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V66A P00533 701 1014 1210.0 QP1:1202 Type1 Inactive DFGin 5.426 16.514 BLBtrans -124.42, 177.95 61.86, 22.75 -59.98, 134.04 162.48, 75.29 88.51, -14.09 out-out out 14.22 Saltbr-out 14.194 HRD-in -77.47, -52.32 80.43, -9.63 out-out-out SNCooo out-out ActLoopNT-out 6.728 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -74.38, -13.47 APE9-dihe-in -92.56, 110.16 APE8-dihe-in -84.07, 69.49 APE8-rot-na 34.36 APE67-dihe-in -75.03, -2.7 -49.4, -44.98 APE12-dist-na 15.483 APE11-dist-na 13.333 APE10-dist-na 9.108 APE9-dist-in 7.409 T790M,V948R None None XRAY 1.79 0.187 0.226 A 327 314 0 0 0 0 [[712, 970]] 1.0 6v66 TYR_EGFR_HUMAN TYR 6e-88 300.6 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V66B P00533 701 1014 1210.0 QP1:1202 Type1 Inactive DFGin 5.419 16.392 BLBtrans -126.49, 176.29 67.7, 20.21 -61.15, 136.48 152.37, 70.68 83.55, -13.04 out-out out 13.94 Saltbr-out 13.622 HRD-in -79.19, -50.94 79.82, -14.47 out-out-out SNCooo out-out ActLoopNT-out 6.943 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, 5.96 APE9-dihe-in -124.61, 120.95 APE8-dihe-in -80.22, 74.26 APE8-rot-na 32.87 APE67-dihe-in -76.34, -6.09 -59.72, -39.51 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.496 APE9-dist-out 8.123 T790M,V948R None None XRAY 1.79 0.187 0.226 B 327 302 12 0 0 12 [[712, 970]] 1.0 6v66 TYR_EGFR_HUMAN TYR 6e-88 300.6 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V66C P00533 701 1012 1210.0 QP1:1101 Type1 Inactive DFGin 5.717 16.359 BLBtrans -124.4, -178.87 63.87, 27.71 -73.72, 147.34 167.32, 74.76 78.96, -14.16 out-out out 13.351 Saltbr-out 12.617 HRD-in -80.32, -46.75 78.9, -11.66 out-out-none SNCoon out-none ActLoopNT-out 7.109 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 126.19 APE8-dihe-in -84.45, 72.53 APE8-rot-na 33.88 APE67-dihe-in -72.73, -2.16 -59.44, -40.55 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.949 T790M,V948R None None XRAY 1.79 0.187 0.226 C 327 299 13 0 0 13 [[712, 970]] 1.0 6v66 TYR_EGFR_HUMAN TYR 6e-88 300.6 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 6V66 — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 3 75.0% 6V66A
DFGin BLBplus 1 25.0% 6V66D
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 6V66D P00533 701 1014 1210.0 QP1:1203 Type1 Inactive DFGin 4.096 13.943 BLBplus -133.25, 173.78 71.02, 17.1 -71.48, 143.37 58.07, 94.52 76.41, -7.86 out-out out 14.093 Saltbr-out 14.181 HRD-in -71.49, -55.9 81.36, -15.85 out-out-out SNCooo out-out ActLoopNT-out 6.527 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -93.31, -7.02 APE9-dihe-in -100.17, 123.42 APE8-dihe-in -79.15, 63.8 APE8-rot-na 32.12 APE67-dihe-in -77.89, -1.58 -50.41, -43.42 APE12-dist-na 18.544 APE11-dist-na 16.043 APE10-dist-na 11.737 APE9-dist-in 7.947 T790M,V948R None None XRAY 1.79 0.187 0.226 D 327 314 0 0 0 0 [[712, 970]] 1.0 6v66 Homo sapiens TYR_EGFR_HUMAN TYR 6e-88 300.6 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V66A P00533 701 1014 1210.0 QP1:1202 Type1 Inactive DFGin 5.426 16.514 BLBtrans -124.42, 177.95 61.86, 22.75 -59.98, 134.04 162.48, 75.29 88.51, -14.09 out-out out 14.22 Saltbr-out 14.194 HRD-in -77.47, -52.32 80.43, -9.63 out-out-out SNCooo out-out ActLoopNT-out 6.728 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -74.38, -13.47 APE9-dihe-in -92.56, 110.16 APE8-dihe-in -84.07, 69.49 APE8-rot-na 34.36 APE67-dihe-in -75.03, -2.7 -49.4, -44.98 APE12-dist-na 15.483 APE11-dist-na 13.333 APE10-dist-na 9.108 APE9-dist-in 7.409 T790M,V948R None None XRAY 1.79 0.187 0.226 A 327 314 0 0 0 0 [[712, 970]] 1.0 6v66 Homo sapiens TYR_EGFR_HUMAN TYR 6e-88 300.6 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V66B P00533 701 1014 1210.0 QP1:1202 Type1 Inactive DFGin 5.419 16.392 BLBtrans -126.49, 176.29 67.7, 20.21 -61.15, 136.48 152.37, 70.68 83.55, -13.04 out-out out 13.94 Saltbr-out 13.622 HRD-in -79.19, -50.94 79.82, -14.47 out-out-out SNCooo out-out ActLoopNT-out 6.943 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, 5.96 APE9-dihe-in -124.61, 120.95 APE8-dihe-in -80.22, 74.26 APE8-rot-na 32.87 APE67-dihe-in -76.34, -6.09 -59.72, -39.51 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.496 APE9-dist-out 8.123 T790M,V948R None None XRAY 1.79 0.187 0.226 B 327 302 12 0 0 12 [[712, 970]] 1.0 6v66 Homo sapiens TYR_EGFR_HUMAN TYR 6e-88 300.6 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V66C P00533 701 1012 1210.0 QP1:1101 Type1 Inactive DFGin 5.717 16.359 BLBtrans -124.4, -178.87 63.87, 27.71 -73.72, 147.34 167.32, 74.76 78.96, -14.16 out-out out 13.351 Saltbr-out 12.617 HRD-in -80.32, -46.75 78.9, -11.66 out-out-none SNCoon out-none ActLoopNT-out 7.109 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 126.19 APE8-dihe-in -84.45, 72.53 APE8-rot-na 33.88 APE67-dihe-in -72.73, -2.16 -59.44, -40.55 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.949 T790M,V948R None None XRAY 1.79 0.187 0.226 C 327 299 13 0 0 13 [[712, 970]] 1.0 6v66 Homo sapiens TYR_EGFR_HUMAN TYR 6e-88 300.6 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 6V66 — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name