PDB: 6TPF — TYR JAK1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 6TPFA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 6TPFA P23458 864 1153 1154.0 NTQ:1201 Type1 Inactive DFGin 6.5489 13.5659 ABAminus -112.13, 4.42 -147.17, 134.74 -132.51, 36.57 297.52, 87.9 -61.56, -38.59 in-in in 7.9072 Saltbr-in 2.7233 HRD-in -81.26, -43.5 66.58, 8.45 in-in-out SNCiio in-out ActLoopNT-in 2.7552 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -113.97, 47.61 APE9-dihe-in -75.75, 153.17 APE8-dihe-in -82.59, 85.83 APE8-rot-na 32.54 APE67-dihe-in -74.51, -8.6 -66.85, -35.11 APE12-dist-na 10.9508 APE11-dist-na 12.7019 APE10-dist-na 10.9448 APE9-dist-in 6.7022 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.31 0.266 0.327 A 291.0 288.0 2 31 31 0 [[583, 847], [875, 1151]] 2.0 6tpf TYR_JAK1-2_HUMAN TYR 1.9e-87 298.8 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6TPFB P23458 865 1153 1154.0 NTQ:1201 Type1 Inactive DFGin 6.5159 13.6075 ABAminus -112.38, 6.69 -146.72, 134.6 -130.81, 35.94 297.58, 85.61 -65.62, -37.25 in-in in 7.8432 Saltbr-in 2.7199 HRD-in -83.36, -42.45 66.49, 9.9 in-in-out SNCiio in-out ActLoopNT-in 2.7624 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out 46.13, 45.8 APE9-dihe-in -71.68, 152.43 APE8-dihe-in -82.66, 85.94 APE8-rot-na 32.5 APE67-dihe-in -74.85, -9.43 -66.05, -35.76 APE12-dist-na 10.9678 APE11-dist-na 12.3423 APE10-dist-na 11.4191 APE9-dist-in 6.666 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.31 0.266 0.327 B 291.0 278.0 11 31 31 0 [[583, 847], [875, 1151]] 2.0 6tpf TYR_JAK1-2_HUMAN TYR 1.9e-87 298.8 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

PDB: 6TPF — TYR JAK1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 6TPFA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 6TPFA P23458 864 1153 1154.0 NTQ:1201 Type1 Inactive DFGin 6.5489 13.5659 ABAminus -112.13, 4.42 -147.17, 134.74 -132.51, 36.57 297.52, 87.9 -61.56, -38.59 in-in in 7.9072 Saltbr-in 2.7233 HRD-in -81.26, -43.5 66.58, 8.45 in-in-out SNCiio in-out ActLoopNT-in 2.7552 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -113.97, 47.61 APE9-dihe-in -75.75, 153.17 APE8-dihe-in -82.59, 85.83 APE8-rot-na 32.54 APE67-dihe-in -74.51, -8.6 -66.85, -35.11 APE12-dist-na 10.9508 APE11-dist-na 12.7019 APE10-dist-na 10.9448 APE9-dist-in 6.7022 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.31 0.266 0.327 A 291.0 288.0 2 31 31 0 [[583, 847], [875, 1151]] 2.0 6tpf Homo sapiens TYR_JAK1-2_HUMAN TYR 1.9e-87 298.8 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6TPFB P23458 865 1153 1154.0 NTQ:1201 Type1 Inactive DFGin 6.5159 13.6075 ABAminus -112.38, 6.69 -146.72, 134.6 -130.81, 35.94 297.58, 85.61 -65.62, -37.25 in-in in 7.8432 Saltbr-in 2.7199 HRD-in -83.36, -42.45 66.49, 9.9 in-in-out SNCiio in-out ActLoopNT-in 2.7624 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out 46.13, 45.8 APE9-dihe-in -71.68, 152.43 APE8-dihe-in -82.66, 85.94 APE8-rot-na 32.5 APE67-dihe-in -74.85, -9.43 -66.05, -35.76 APE12-dist-na 10.9678 APE11-dist-na 12.3423 APE10-dist-na 11.4191 APE9-dist-in 6.666 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.31 0.266 0.327 B 291.0 278.0 11 31 31 0 [[583, 847], [875, 1151]] 2.0 6tpf Homo sapiens TYR_JAK1-2_HUMAN TYR 1.9e-87 298.8 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

PDB: 6TPF — TYR JAK1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name