PDB: 6TPE — TYR JAK1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 6TPEA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 6TPEA P23458 864 1153 1154.0 NTW:1201 Type1 Inactive DFGin 6.4521 13.4517 ABAminus -113.52, 27.97 -159.85, 137.75 -139.89, 37.69 300.95, 90.85 -70.73, -32.53 in-in in 7.9845 Saltbr-in 2.8979 HRD-in -77.39, -48.43 67.11, 20.0 in-in-in SNCiii in-in ActLoopNT-in 2.7214 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -109.39, 82.51 APE9-dihe-in -109.84, 138.7 APE8-dihe-in -71.54, 85.2 APE8-rot-na 346.93 APE67-dihe-in -79.64, -10.25 -64.68, -30.27 APE12-dist-na 10.1252 APE11-dist-na 12.1296 APE10-dist-na 10.4977 APE9-dist-in 6.4525 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.87 0.249 0.298 A 291.0 283.0 7 31 31 0 [[583, 847], [875, 1151]] 2.0 6tpe TYR_JAK1-2_HUMAN TYR 1.9e-87 298.8 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6TPEB P23458 864 1154 1154.0 NTW:1201 Type1 Inactive DFGin 6.4487 13.4616 ABAminus -113.4, 27.83 -159.97, 137.64 -139.8, 37.79 300.87, 90.88 -70.61, -32.51 in-in in 7.9939 Saltbr-in 2.8934 HRD-in -77.28, -48.49 67.12, 19.91 in-in-in SNCiii in-in ActLoopNT-in 2.7232 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -109.48, 82.82 APE9-dihe-in -109.8, 138.58 APE8-dihe-in -71.3, 85.03 APE8-rot-na 346.96 APE67-dihe-in -79.6, -10.33 -64.53, -30.29 APE12-dist-na 10.1332 APE11-dist-na 12.1297 APE10-dist-na 10.5127 APE9-dist-in 6.4531 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.87 0.249 0.298 B 291.0 283.0 8 31 31 0 [[583, 847], [875, 1151]] 2.0 6tpe TYR_JAK1-2_HUMAN TYR 1.9e-87 298.8 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

PDB: 6TPE — TYR JAK1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 6TPEA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 6TPEA P23458 864 1153 1154.0 NTW:1201 Type1 Inactive DFGin 6.4521 13.4517 ABAminus -113.52, 27.97 -159.85, 137.75 -139.89, 37.69 300.95, 90.85 -70.73, -32.53 in-in in 7.9845 Saltbr-in 2.8979 HRD-in -77.39, -48.43 67.11, 20.0 in-in-in SNCiii in-in ActLoopNT-in 2.7214 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -109.39, 82.51 APE9-dihe-in -109.84, 138.7 APE8-dihe-in -71.54, 85.2 APE8-rot-na 346.93 APE67-dihe-in -79.64, -10.25 -64.68, -30.27 APE12-dist-na 10.1252 APE11-dist-na 12.1296 APE10-dist-na 10.4977 APE9-dist-in 6.4525 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.87 0.249 0.298 A 291.0 283.0 7 31 31 0 [[583, 847], [875, 1151]] 2.0 6tpe Homo sapiens TYR_JAK1-2_HUMAN TYR 1.9e-87 298.8 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6TPEB P23458 864 1154 1154.0 NTW:1201 Type1 Inactive DFGin 6.4487 13.4616 ABAminus -113.4, 27.83 -159.97, 137.64 -139.8, 37.79 300.87, 90.88 -70.61, -32.51 in-in in 7.9939 Saltbr-in 2.8934 HRD-in -77.28, -48.49 67.12, 19.91 in-in-in SNCiii in-in ActLoopNT-in 2.7232 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -109.48, 82.82 APE9-dihe-in -109.8, 138.58 APE8-dihe-in -71.3, 85.03 APE8-rot-na 346.96 APE67-dihe-in -79.6, -10.33 -64.53, -30.29 APE12-dist-na 10.1332 APE11-dist-na 12.1297 APE10-dist-na 10.5127 APE9-dist-in 6.4531 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.87 0.249 0.298 B 291.0 283.0 8 31 31 0 [[583, 847], [875, 1151]] 2.0 6tpe Homo sapiens TYR_JAK1-2_HUMAN TYR 1.9e-87 298.8 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

PDB: 6TPE — TYR JAK1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name