PDB: 6TIA — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6TIAA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 6TIAA Q9NWZ3 163 459 460.0 ND2:501,ND2:502,ND2:503,ND2:504 Type1,Allosteric,Allosteric,Allosteric Inactive DFGin 7.0563 14.7895 BLAminus -140.42, -178.87 56.13, 87.79 -104.25, 13.99 300.74, 95.94 -61.47, -11.04 in-out in 9.4587 Saltbr-out 6.4913 HRD-in -66.38, -48.88 73.85, 2.56 out-in-in SNCoii in-in ActLoopNT-in 2.803 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.91, 156.52 APE9-dihe-na 134.49, -171.44 APE8-dihe-in -101.75, 121.09 APE8-rot-in 313.72 APE67-dihe-in -68.2, -12.58 -55.04, -41.75 APE12-dist-in 10.3144 APE11-dist-in 11.8851 APE10-dist-in 6.4879 APE9-dist-in 3.5476 None TPO345,SEP346 TPO345,SEP346 XRAY 2.52 0.218 0.261 A 308.0 288.0 9 30 24 6 [[183, 456]] 1.0 6tia TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6TIAB Q9NWZ3 164 459 460.0 ND2:501,ND2:502,ND2:503,ND2:504 Type1,Allosteric,Allosteric,Allosteric Inactive DFGin 7.0823 14.767 BLAminus -129.53, 179.91 56.34, 87.3 -105.34, 14.83 301.91, 95.46 -60.96, -19.27 in-out in 9.2422 Saltbr-out 7.2036 HRD-in -65.06, -49.58 73.65, 2.87 out-in-in SNCoii in-in ActLoopNT-in 2.8143 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.9, 155.88 APE9-dihe-na 135.29, -171.62 APE8-dihe-in -102.71, 120.99 APE8-rot-in 315.19 APE67-dihe-in -67.65, -13.42 -54.79, -41.81 APE12-dist-in 10.2844 APE11-dist-in 11.9206 APE10-dist-in 6.518 APE9-dist-in 3.6049 None TPO345,SEP346 TPO345,SEP346 XRAY 2.52 0.218 0.261 B 308.0 287.0 9 30 24 6 [[183, 456]] 1.0 6tia TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 6TIA — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6TIAA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 6TIAA Q9NWZ3 163 459 460.0 ND2:501,ND2:502,ND2:503,ND2:504 Type1,Allosteric,Allosteric,Allosteric Inactive DFGin 7.0563 14.7895 BLAminus -140.42, -178.87 56.13, 87.79 -104.25, 13.99 300.74, 95.94 -61.47, -11.04 in-out in 9.4587 Saltbr-out 6.4913 HRD-in -66.38, -48.88 73.85, 2.56 out-in-in SNCoii in-in ActLoopNT-in 2.803 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.91, 156.52 APE9-dihe-na 134.49, -171.44 APE8-dihe-in -101.75, 121.09 APE8-rot-in 313.72 APE67-dihe-in -68.2, -12.58 -55.04, -41.75 APE12-dist-in 10.3144 APE11-dist-in 11.8851 APE10-dist-in 6.4879 APE9-dist-in 3.5476 None TPO345,SEP346 TPO345,SEP346 XRAY 2.52 0.218 0.261 A 308.0 288.0 9 30 24 6 [[183, 456]] 1.0 6tia Homo sapiens TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6TIAB Q9NWZ3 164 459 460.0 ND2:501,ND2:502,ND2:503,ND2:504 Type1,Allosteric,Allosteric,Allosteric Inactive DFGin 7.0823 14.767 BLAminus -129.53, 179.91 56.34, 87.3 -105.34, 14.83 301.91, 95.46 -60.96, -19.27 in-out in 9.2422 Saltbr-out 7.2036 HRD-in -65.06, -49.58 73.65, 2.87 out-in-in SNCoii in-in ActLoopNT-in 2.8143 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.9, 155.88 APE9-dihe-na 135.29, -171.62 APE8-dihe-in -102.71, 120.99 APE8-rot-in 315.19 APE67-dihe-in -67.65, -13.42 -54.79, -41.81 APE12-dist-in 10.2844 APE11-dist-in 11.9206 APE10-dist-in 6.518 APE9-dist-in 3.6049 None TPO345,SEP346 TPO345,SEP346 XRAY 2.52 0.218 0.261 B 308.0 287.0 9 30 24 6 [[183, 456]] 1.0 6tia Homo sapiens TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 6TIA — TKL IRAK4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name