PDB: 6RSC — TYR JAK1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 6RSCA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 6RSCA P23458 865 1154 1154.0 KH5:1201 Type1 Inactive DFGin 6.5538 13.4092 ABAminus -117.31, 8.47 -153.39, 137.28 -129.48, 30.56 297.53, 83.92 -65.76, -23.88 in-in in 7.6629 Saltbr-in 2.6894 HRD-in -79.6, -49.32 70.06, 11.43 in-in-out SNCiio in-out ActLoopNT-in 2.7172 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -98.9, 27.5 APE9-dihe-in -67.04, 137.63 APE8-dihe-in -80.21, 78.36 APE8-rot-na 37.08 APE67-dihe-in -76.89, -0.21 -62.94, -28.86 APE12-dist-na 11.0035 APE11-dist-na 13.5759 APE10-dist-na 10.2308 APE9-dist-in 6.8584 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.85 0.249 0.28 A 302.0 286.0 4 31 31 0 [[583, 847], [875, 1151]] 2.0 6rsc TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6RSCB P23458 865 1154 1154.0 KH5:1201 Type1 Inactive DFGin 6.5561 13.712 ABAminus -118.51, -2.16 -150.35, 139.43 -132.07, 31.9 298.68, 77.43 -57.63, -28.0 in-in in 7.9025 Saltbr-in 2.662 HRD-in -78.87, -51.69 73.77, 10.39 in-in-out SNCiio in-out ActLoopNT-in 2.9169 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -100.91, 33.47 APE9-dihe-in -66.35, 135.05 APE8-dihe-in -77.66, 75.63 APE8-rot-na 31.23 APE67-dihe-in -74.4, -5.72 -63.02, -28.16 APE12-dist-na 11.1417 APE11-dist-na 13.5111 APE10-dist-na 10.263 APE9-dist-in 6.9184 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.85 0.249 0.28 B 302.0 281.0 9 31 31 0 [[583, 847], [875, 1151]] 2.0 6rsc TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

PDB: 6RSC — TYR JAK1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 6RSCA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 6RSCA P23458 865 1154 1154.0 KH5:1201 Type1 Inactive DFGin 6.5538 13.4092 ABAminus -117.31, 8.47 -153.39, 137.28 -129.48, 30.56 297.53, 83.92 -65.76, -23.88 in-in in 7.6629 Saltbr-in 2.6894 HRD-in -79.6, -49.32 70.06, 11.43 in-in-out SNCiio in-out ActLoopNT-in 2.7172 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -98.9, 27.5 APE9-dihe-in -67.04, 137.63 APE8-dihe-in -80.21, 78.36 APE8-rot-na 37.08 APE67-dihe-in -76.89, -0.21 -62.94, -28.86 APE12-dist-na 11.0035 APE11-dist-na 13.5759 APE10-dist-na 10.2308 APE9-dist-in 6.8584 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.85 0.249 0.28 A 302.0 286.0 4 31 31 0 [[583, 847], [875, 1151]] 2.0 6rsc Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6RSCB P23458 865 1154 1154.0 KH5:1201 Type1 Inactive DFGin 6.5561 13.712 ABAminus -118.51, -2.16 -150.35, 139.43 -132.07, 31.9 298.68, 77.43 -57.63, -28.0 in-in in 7.9025 Saltbr-in 2.662 HRD-in -78.87, -51.69 73.77, 10.39 in-in-out SNCiio in-out ActLoopNT-in 2.9169 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -100.91, 33.47 APE9-dihe-in -66.35, 135.05 APE8-dihe-in -77.66, 75.63 APE8-rot-na 31.23 APE67-dihe-in -74.4, -5.72 -63.02, -28.16 APE12-dist-na 11.1417 APE11-dist-na 13.5111 APE10-dist-na 10.263 APE9-dist-in 6.9184 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.85 0.249 0.28 B 302.0 281.0 9 31 31 0 [[583, 847], [875, 1151]] 2.0 6rsc Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

PDB: 6RSC — TYR JAK1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name