| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | FGFR1 | FGFR1_HUMAN | 6P68A | P11362 | 462 | 763 | 822.0 | O1Y:801 | Type1.5_Back | Inactive | DFGin | 5.5681 | 13.2974 | BLAplus | -124.18, 155.54 | 63.3, 48.78 | -90.25, -51.15 | 37.68, 89.45 | -72.78, 42.85 | in-in | in | 8.4634 | Saltbr-in | 3.0682 | HRD-in | -82.33, -55.3 | 90.45, -28.65 | in-out-out | SNCioo | out-out | ActLoopNT-out | 9.2537 | ActLoopCT-out | TYR | APEdihe_iioai | APEdist_aaao | APE10-dihe-in | -84.44, 166.09 | APE9-dihe-in | -115.93, 115.43 | APE8-dihe-out | -43.99, -17.59 | APE8-rot-na | 319.34 | APE67-dihe-in | -77.38, -22.95 | -75.44, -11.63 | APE12-dist-na | 20.7136 | APE11-dist-na | 21.7563 | APE10-dist-na | 19.6548 | APE9-dist-out | 11.5919 | C488A,Y563C | None | None | XRAY | 2.9 | 0.23 | 0.303 | A | 309.0 | 287.0 | 15 | 30 | 27 | 3 | [[478, 756]] | 1.0 | 6p68 | TYR_FGFR1_HUMAN | TYR | 1.5e-103 | 351.6 | 1.0 | 260.0 | 260.0 | 640 | 641 | 642 | 644 | 646 | 514 | 531 | 535 | 620 | 622 | 621 | 623.0 | 682 | 670 | 665 | 664 | 663 | 662 | 661 | 660 | 659 | 562 | Fibroblast growth factor receptor 1 |
| TYR | FGFR1 | FGFR1_HUMAN | 6P68B | P11362 | 462 | 763 | 822.0 | O1Y:801 | Type1.5_Back | Inactive | DFGin | 5.4999 | 13.3623 | BLAplus | -127.31, 162.51 | 46.96, 56.83 | -101.23, -42.4 | 47.99, 77.97 | -84.27, 46.6 | in-in | in | 7.7578 | Saltbr-in | 3.3016 | HRD-in | -84.02, -53.61 | 84.39, -26.28 | in-out-out | SNCioo | out-out | ActLoopNT-out | 8.8458 | ActLoopCT-out | TYR | APEdihe_iioai | APEdist_aaao | APE10-dihe-in | -97.18, 175.15 | APE9-dihe-in | -113.49, 131.98 | APE8-dihe-out | -57.6, -24.27 | APE8-rot-na | 330.67 | APE67-dihe-in | -68.05, -15.43 | -68.07, -21.93 | APE12-dist-na | 20.753 | APE11-dist-na | 22.1816 | APE10-dist-na | 20.562 | APE9-dist-out | 11.6663 | C488A,Y563C | None | None | XRAY | 2.9 | 0.23 | 0.303 | B | 309.0 | 286.0 | 16 | 30 | 27 | 3 | [[478, 756]] | 1.0 | 6p68 | TYR_FGFR1_HUMAN | TYR | 1.5e-103 | 351.6 | 1.0 | 260.0 | 260.0 | 640 | 641 | 642 | 644 | 646 | 514 | 531 | 535 | 620 | 622 | 621 | 623.0 | 682 | 670 | 665 | 664 | 663 | 662 | 661 | 660 | 659 | 562 | Fibroblast growth factor receptor 1 |
| TYR | FGFR1 | FGFR1_HUMAN | 6P68C | P11362 | 463 | 763 | 822.0 | O1Y:801 | Type1.5_Back | Inactive | DFGin | 5.8214 | 13.2159 | BLAplus | -111.29, 171.43 | 44.74, 37.04 | -76.15, -58.04 | 39.05, 94.26 | -70.98, 63.26 | in-in | in | 7.3725 | Saltbr-in | 2.8855 | HRD-in | -80.62, -45.97 | 77.53, -19.73 | in-out-out | SNCioo | out-out | ActLoopNT-out | 8.2897 | ActLoopCT-out | TYR | APEdihe_iioai | APEdist_aaao | APE10-dihe-in | -107.73, 161.83 | APE9-dihe-in | -111.63, 125.51 | APE8-dihe-out | -59.61, -24.78 | APE8-rot-na | 332.23 | APE67-dihe-in | -70.27, -21.8 | -56.16, -23.37 | APE12-dist-na | 20.3359 | APE11-dist-na | 21.4418 | APE10-dist-na | 19.2263 | APE9-dist-out | 11.3243 | C488A,Y563C | None | None | XRAY | 2.9 | 0.23 | 0.303 | C | 309.0 | 286.0 | 15 | 30 | 27 | 3 | [[478, 756]] | 1.0 | 6p68 | TYR_FGFR1_HUMAN | TYR | 1.5e-103 | 351.6 | 1.0 | 260.0 | 260.0 | 640 | 641 | 642 | 644 | 646 | 514 | 531 | 535 | 620 | 622 | 621 | 623.0 | 682 | 670 | 665 | 664 | 663 | 662 | 661 | 660 | 659 | 562 | Fibroblast growth factor receptor 1 |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | FGFR1 | FGFR1_HUMAN | 6P68A | P11362 | 462 | 763 | 822.0 | O1Y:801 | Type1.5_Back | Inactive | DFGin | 5.5681 | 13.2974 | BLAplus | -124.18, 155.54 | 63.3, 48.78 | -90.25, -51.15 | 37.68, 89.45 | -72.78, 42.85 | in-in | in | 8.4634 | Saltbr-in | 3.0682 | HRD-in | -82.33, -55.3 | 90.45, -28.65 | in-out-out | SNCioo | out-out | ActLoopNT-out | 9.2537 | ActLoopCT-out | TYR | APEdihe_iioai | APEdist_aaao | APE10-dihe-in | -84.44, 166.09 | APE9-dihe-in | -115.93, 115.43 | APE8-dihe-out | -43.99, -17.59 | APE8-rot-na | 319.34 | APE67-dihe-in | -77.38, -22.95 | -75.44, -11.63 | APE12-dist-na | 20.7136 | APE11-dist-na | 21.7563 | APE10-dist-na | 19.6548 | APE9-dist-out | 11.5919 | C488A,Y563C | None | None | XRAY | 2.9 | 0.23 | 0.303 | A | 309.0 | 287.0 | 15 | 30 | 27 | 3 | [[478, 756]] | 1.0 | 6p68 | Homo sapiens | TYR_FGFR1_HUMAN | TYR | 1.5e-103 | 351.6 | 1.0 | 260.0 | 260.0 | 640 | 641 | 642 | 644 | 646 | 514 | 531 | 535 | 620 | 622 | 621 | 623.0 | 682 | 670 | 665 | 664 | 663 | 662 | 661 | 660 | 659 | 562 | Fibroblast growth factor receptor 1 |
| TYR | FGFR1 | FGFR1_HUMAN | 6P68B | P11362 | 462 | 763 | 822.0 | O1Y:801 | Type1.5_Back | Inactive | DFGin | 5.4999 | 13.3623 | BLAplus | -127.31, 162.51 | 46.96, 56.83 | -101.23, -42.4 | 47.99, 77.97 | -84.27, 46.6 | in-in | in | 7.7578 | Saltbr-in | 3.3016 | HRD-in | -84.02, -53.61 | 84.39, -26.28 | in-out-out | SNCioo | out-out | ActLoopNT-out | 8.8458 | ActLoopCT-out | TYR | APEdihe_iioai | APEdist_aaao | APE10-dihe-in | -97.18, 175.15 | APE9-dihe-in | -113.49, 131.98 | APE8-dihe-out | -57.6, -24.27 | APE8-rot-na | 330.67 | APE67-dihe-in | -68.05, -15.43 | -68.07, -21.93 | APE12-dist-na | 20.753 | APE11-dist-na | 22.1816 | APE10-dist-na | 20.562 | APE9-dist-out | 11.6663 | C488A,Y563C | None | None | XRAY | 2.9 | 0.23 | 0.303 | B | 309.0 | 286.0 | 16 | 30 | 27 | 3 | [[478, 756]] | 1.0 | 6p68 | Homo sapiens | TYR_FGFR1_HUMAN | TYR | 1.5e-103 | 351.6 | 1.0 | 260.0 | 260.0 | 640 | 641 | 642 | 644 | 646 | 514 | 531 | 535 | 620 | 622 | 621 | 623.0 | 682 | 670 | 665 | 664 | 663 | 662 | 661 | 660 | 659 | 562 | Fibroblast growth factor receptor 1 |
| TYR | FGFR1 | FGFR1_HUMAN | 6P68C | P11362 | 463 | 763 | 822.0 | O1Y:801 | Type1.5_Back | Inactive | DFGin | 5.8214 | 13.2159 | BLAplus | -111.29, 171.43 | 44.74, 37.04 | -76.15, -58.04 | 39.05, 94.26 | -70.98, 63.26 | in-in | in | 7.3725 | Saltbr-in | 2.8855 | HRD-in | -80.62, -45.97 | 77.53, -19.73 | in-out-out | SNCioo | out-out | ActLoopNT-out | 8.2897 | ActLoopCT-out | TYR | APEdihe_iioai | APEdist_aaao | APE10-dihe-in | -107.73, 161.83 | APE9-dihe-in | -111.63, 125.51 | APE8-dihe-out | -59.61, -24.78 | APE8-rot-na | 332.23 | APE67-dihe-in | -70.27, -21.8 | -56.16, -23.37 | APE12-dist-na | 20.3359 | APE11-dist-na | 21.4418 | APE10-dist-na | 19.2263 | APE9-dist-out | 11.3243 | C488A,Y563C | None | None | XRAY | 2.9 | 0.23 | 0.303 | C | 309.0 | 286.0 | 15 | 30 | 27 | 3 | [[478, 756]] | 1.0 | 6p68 | Homo sapiens | TYR_FGFR1_HUMAN | TYR | 1.5e-103 | 351.6 | 1.0 | 260.0 | 260.0 | 640 | 641 | 642 | 644 | 646 | 514 | 531 | 535 | 620 | 622 | 621 | 623.0 | 682 | 670 | 665 | 664 | 663 | 662 | 661 | 660 | 659 | 562 | Fibroblast growth factor receptor 1 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|