PDB: 6O94 — TKL IRAK4_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6O94A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 6O94A Q9NWZ3 163 458 460.0 LRS:502 Type1 Inactive DFGin 6.9797 13.9567 BLAminus -123.25, 179.18 58.62, 91.23 -110.31, 12.12 305.58, 96.78 -63.69, -27.63 in-out in 9.1142 Saltbr-out 5.0245 HRD-in -68.39, -52.68 75.29, -1.68 out-in-in SNCoii in-in ActLoopNT-in 2.8366 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.99, 140.47 APE9-dihe-na 148.46, -177.74 APE8-dihe-in -101.2, 107.55 APE8-rot-in 306.34 APE67-dihe-in -55.1, -20.47 -45.77, -47.94 APE12-dist-in 10.0718 APE11-dist-in 12.0661 APE10-dist-in 7.3254 APE9-dist-in 5.2183 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 1.98 0.184 0.215 A 320.0 292.0 4 30 26 4 [[183, 456]] 1.0 6o94 TKL_IRAK4_HUMAN TKL 5.1e-84 287.9 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O94B Q9NWZ3 162 458 460.0 LRS:502 Type1 Inactive DFGin 6.899 14.0279 BLAminus -122.58, 179.95 63.12, 86.64 -108.65, 9.89 303.71, 93.33 -58.6, -27.16 in-out in 8.998 Saltbr-out 4.9134 HRD-in -65.66, -51.1 74.78, 1.16 out-in-in SNCoii in-in ActLoopNT-in 2.8194 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.21, 144.66 APE9-dihe-na 140.06, 177.25 APE8-dihe-in -95.53, 110.29 APE8-rot-in 309.4 APE67-dihe-in -63.88, -19.8 -59.96, -25.96 APE12-dist-in 10.2683 APE11-dist-in 12.0988 APE10-dist-in 7.0791 APE9-dist-in 4.8461 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 1.98 0.184 0.215 B 320.0 293.0 4 30 26 4 [[183, 456]] 1.0 6o94 TKL_IRAK4_HUMAN TKL 5.1e-84 287.9 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O94C Q9NWZ3 163 458 460.0 LRS:501 Type1 Inactive DFGin 6.5899 14.128 BLAminus -121.22, 176.46 62.3, 93.01 -113.1, 16.55 308.78, 90.13 -63.81, -32.68 in-out in 8.6856 Saltbr-out 4.062 HRD-in -68.33, -51.83 77.7, -5.17 out-in-in SNCoii in-in ActLoopNT-in 2.7983 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.28, 149.13 APE9-dihe-na 136.69, -178.03 APE8-dihe-in -101.68, 113.37 APE8-rot-in 311.59 APE67-dihe-in -65.13, -21.18 -43.64, -46.59 APE12-dist-in 9.9441 APE11-dist-in 12.0198 APE10-dist-in 6.6751 APE9-dist-in 4.3492 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 1.98 0.184 0.215 C 320.0 286.0 10 30 26 4 [[183, 456]] 1.0 6o94 TKL_IRAK4_HUMAN TKL 5.1e-84 287.9 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O94D Q9NWZ3 163 458 460.0 LRS:501 Type1 Inactive DFGin 7.0029 14.0207 BLAminus -126.53, 176.59 61.66, 94.12 -114.42, 13.3 307.72, 104.0 -58.57, -29.78 in-out in 8.9166 Saltbr-out 4.8918 HRD-in -70.14, -50.46 72.65, -1.5 out-in-in SNCoii in-in ActLoopNT-in 2.7844 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -122.81, 156.44 APE9-dihe-na 122.83, -176.0 APE8-dihe-in -107.14, 110.01 APE8-rot-in 318.74 APE67-dihe-in -57.74, -23.07 -42.07, -49.71 APE12-dist-in 10.2874 APE11-dist-in 12.0683 APE10-dist-in 6.673 APE9-dist-in 4.3687 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 1.98 0.184 0.215 D 320.0 285.0 11 30 25 5 [[183, 456]] 1.0 6o94 TKL_IRAK4_HUMAN TKL 5.1e-84 287.9 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 6O94 — TKL IRAK4_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6O94A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 6O94A Q9NWZ3 163 458 460.0 LRS:502 Type1 Inactive DFGin 6.9797 13.9567 BLAminus -123.25, 179.18 58.62, 91.23 -110.31, 12.12 305.58, 96.78 -63.69, -27.63 in-out in 9.1142 Saltbr-out 5.0245 HRD-in -68.39, -52.68 75.29, -1.68 out-in-in SNCoii in-in ActLoopNT-in 2.8366 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.99, 140.47 APE9-dihe-na 148.46, -177.74 APE8-dihe-in -101.2, 107.55 APE8-rot-in 306.34 APE67-dihe-in -55.1, -20.47 -45.77, -47.94 APE12-dist-in 10.0718 APE11-dist-in 12.0661 APE10-dist-in 7.3254 APE9-dist-in 5.2183 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 1.98 0.184 0.215 A 320.0 292.0 4 30 26 4 [[183, 456]] 1.0 6o94 Homo sapiens TKL_IRAK4_HUMAN TKL 5.1e-84 287.9 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O94B Q9NWZ3 162 458 460.0 LRS:502 Type1 Inactive DFGin 6.899 14.0279 BLAminus -122.58, 179.95 63.12, 86.64 -108.65, 9.89 303.71, 93.33 -58.6, -27.16 in-out in 8.998 Saltbr-out 4.9134 HRD-in -65.66, -51.1 74.78, 1.16 out-in-in SNCoii in-in ActLoopNT-in 2.8194 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.21, 144.66 APE9-dihe-na 140.06, 177.25 APE8-dihe-in -95.53, 110.29 APE8-rot-in 309.4 APE67-dihe-in -63.88, -19.8 -59.96, -25.96 APE12-dist-in 10.2683 APE11-dist-in 12.0988 APE10-dist-in 7.0791 APE9-dist-in 4.8461 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 1.98 0.184 0.215 B 320.0 293.0 4 30 26 4 [[183, 456]] 1.0 6o94 Homo sapiens TKL_IRAK4_HUMAN TKL 5.1e-84 287.9 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O94C Q9NWZ3 163 458 460.0 LRS:501 Type1 Inactive DFGin 6.5899 14.128 BLAminus -121.22, 176.46 62.3, 93.01 -113.1, 16.55 308.78, 90.13 -63.81, -32.68 in-out in 8.6856 Saltbr-out 4.062 HRD-in -68.33, -51.83 77.7, -5.17 out-in-in SNCoii in-in ActLoopNT-in 2.7983 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.28, 149.13 APE9-dihe-na 136.69, -178.03 APE8-dihe-in -101.68, 113.37 APE8-rot-in 311.59 APE67-dihe-in -65.13, -21.18 -43.64, -46.59 APE12-dist-in 9.9441 APE11-dist-in 12.0198 APE10-dist-in 6.6751 APE9-dist-in 4.3492 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 1.98 0.184 0.215 C 320.0 286.0 10 30 26 4 [[183, 456]] 1.0 6o94 Homo sapiens TKL_IRAK4_HUMAN TKL 5.1e-84 287.9 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O94D Q9NWZ3 163 458 460.0 LRS:501 Type1 Inactive DFGin 7.0029 14.0207 BLAminus -126.53, 176.59 61.66, 94.12 -114.42, 13.3 307.72, 104.0 -58.57, -29.78 in-out in 8.9166 Saltbr-out 4.8918 HRD-in -70.14, -50.46 72.65, -1.5 out-in-in SNCoii in-in ActLoopNT-in 2.7844 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -122.81, 156.44 APE9-dihe-na 122.83, -176.0 APE8-dihe-in -107.14, 110.01 APE8-rot-in 318.74 APE67-dihe-in -57.74, -23.07 -42.07, -49.71 APE12-dist-in 10.2874 APE11-dist-in 12.0683 APE10-dist-in 6.673 APE9-dist-in 4.3687 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 1.98 0.184 0.215 D 320.0 285.0 11 30 25 5 [[183, 456]] 1.0 6o94 Homo sapiens TKL_IRAK4_HUMAN TKL 5.1e-84 287.9 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 6O94 — TKL IRAK4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name