PDB: 6O8U — TKL IRAK4_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6O8UC
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 6O8UA Q9NWZ3 164 458 460.0 LS7:501 Type1 Inactive DFGin 6.85 13.924 BLAminus -130.69, 173.07 63.01, 86.37 -108.36, 22.19 311.43, 95.51 -64.92, -32.76 in-out in 8.745 Saltbr-out 5.586 HRD-in -75.11, -49.45 74.88, -0.72 out-in-in SNCoii in-in ActLoopNT-in 2.814 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -124.91, 157.66 APE9-dihe-na 128.13, 175.66 APE8-dihe-in -101.58, 115.34 APE8-rot-in 306.32 APE67-dihe-in -62.48, -19.12 -53.1, -39.45 APE12-dist-in 10.265 APE11-dist-in 11.899 APE10-dist-in 6.392 APE9-dist-in 3.938 None TPO345,SEP346 TPO345,SEP346 XRAY 1.8 0.232 0.255 A 305 283 12 0 0 6 [[183, 456]] 1.0 6o8u TKL_IRAK4_HUMAN TKL 4.3e-84 288.1 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O8UB Q9NWZ3 160 458 460.0 LS7:501 Type1 Inactive DFGin 6.746 14.325 BLAminus -126.54, 176.56 64.22, 88.45 -115.23, 24.91 305.83, 84.08 -70.08, -44.03 in-out in 8.887 Saltbr-out 4.662 HRD-in -67.93, -50.14 73.94, 8.33 out-in-in SNCoii in-in ActLoopNT-in 2.883 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.94, 156.88 APE9-dihe-na 130.39, -170.17 APE8-dihe-in -111.3, 117.6 APE8-rot-in 309.78 APE67-dihe-in -67.89, -15.82 -48.54, -45.93 APE12-dist-in 10.402 APE11-dist-in 11.91 APE10-dist-in 6.566 APE9-dist-in 4.161 None TPO345,SEP346 TPO345,SEP346 XRAY 1.8 0.232 0.255 B 305 286 13 0 0 7 [[183, 456]] 1.0 6o8u TKL_IRAK4_HUMAN TKL 4.3e-84 288.1 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O8UC Q9NWZ3 163 458 460.0 LS7:501 Type1 Inactive DFGin 6.786 13.903 BLAminus -128.29, 176.07 64.24, 85.11 -109.32, 20.81 312.79, 96.26 -63.76, -35.39 in-out in 8.962 Saltbr-out 5.215 HRD-in -75.57, -52.02 75.43, 8.91 out-in-in SNCoii in-in ActLoopNT-in 2.806 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.09, 151.89 APE9-dihe-na 134.27, -175.85 APE8-dihe-in -100.31, 112.85 APE8-rot-in 307.74 APE67-dihe-in -64.12, -18.09 -55.7, -37.12 APE12-dist-in 9.921 APE11-dist-in 12.075 APE10-dist-in 7.128 APE9-dist-in 4.813 None TPO345,SEP346 TPO345,SEP346 XRAY 1.8 0.232 0.255 C 305 292 4 0 0 4 [[183, 456]] 1.0 6o8u TKL_IRAK4_HUMAN TKL 4.3e-84 288.1 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O8UD Q9NWZ3 162 458 460.0 LS7:501 Type1 Inactive DFGin 6.686 13.956 BLAminus -123.57, 176.25 66.06, 85.61 -109.09, 18.14 308.14, 93.15 -62.5, -37.48 in-out in 9.039 Saltbr-out 4.98 HRD-in -73.18, -49.75 72.94, 10.03 out-in-in SNCoii in-in ActLoopNT-in 2.847 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.37, 151.31 APE9-dihe-na 137.68, -175.61 APE8-dihe-in -104.71, 113.88 APE8-rot-in 306.99 APE67-dihe-in -63.19, -22.97 -60.18, -27.94 APE12-dist-in 9.959 APE11-dist-in 11.834 APE10-dist-in 6.908 APE9-dist-in 4.658 None TPO345,SEP346 TPO345,SEP346 XRAY 1.8 0.232 0.255 D 305 290 7 0 0 6 [[183, 456]] 1.0 6o8u TKL_IRAK4_HUMAN TKL 4.3e-84 288.1 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 6O8U — TKL IRAK4_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6O8UC
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 6O8UA Q9NWZ3 164 458 460.0 LS7:501 Type1 Inactive DFGin 6.85 13.924 BLAminus -130.69, 173.07 63.01, 86.37 -108.36, 22.19 311.43, 95.51 -64.92, -32.76 in-out in 8.745 Saltbr-out 5.586 HRD-in -75.11, -49.45 74.88, -0.72 out-in-in SNCoii in-in ActLoopNT-in 2.814 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -124.91, 157.66 APE9-dihe-na 128.13, 175.66 APE8-dihe-in -101.58, 115.34 APE8-rot-in 306.32 APE67-dihe-in -62.48, -19.12 -53.1, -39.45 APE12-dist-in 10.265 APE11-dist-in 11.899 APE10-dist-in 6.392 APE9-dist-in 3.938 None TPO345,SEP346 TPO345,SEP346 XRAY 1.8 0.232 0.255 A 305 283 12 0 0 6 [[183, 456]] 1.0 6o8u Homo sapiens TKL_IRAK4_HUMAN TKL 4.3e-84 288.1 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O8UB Q9NWZ3 160 458 460.0 LS7:501 Type1 Inactive DFGin 6.746 14.325 BLAminus -126.54, 176.56 64.22, 88.45 -115.23, 24.91 305.83, 84.08 -70.08, -44.03 in-out in 8.887 Saltbr-out 4.662 HRD-in -67.93, -50.14 73.94, 8.33 out-in-in SNCoii in-in ActLoopNT-in 2.883 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.94, 156.88 APE9-dihe-na 130.39, -170.17 APE8-dihe-in -111.3, 117.6 APE8-rot-in 309.78 APE67-dihe-in -67.89, -15.82 -48.54, -45.93 APE12-dist-in 10.402 APE11-dist-in 11.91 APE10-dist-in 6.566 APE9-dist-in 4.161 None TPO345,SEP346 TPO345,SEP346 XRAY 1.8 0.232 0.255 B 305 286 13 0 0 7 [[183, 456]] 1.0 6o8u Homo sapiens TKL_IRAK4_HUMAN TKL 4.3e-84 288.1 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O8UC Q9NWZ3 163 458 460.0 LS7:501 Type1 Inactive DFGin 6.786 13.903 BLAminus -128.29, 176.07 64.24, 85.11 -109.32, 20.81 312.79, 96.26 -63.76, -35.39 in-out in 8.962 Saltbr-out 5.215 HRD-in -75.57, -52.02 75.43, 8.91 out-in-in SNCoii in-in ActLoopNT-in 2.806 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.09, 151.89 APE9-dihe-na 134.27, -175.85 APE8-dihe-in -100.31, 112.85 APE8-rot-in 307.74 APE67-dihe-in -64.12, -18.09 -55.7, -37.12 APE12-dist-in 9.921 APE11-dist-in 12.075 APE10-dist-in 7.128 APE9-dist-in 4.813 None TPO345,SEP346 TPO345,SEP346 XRAY 1.8 0.232 0.255 C 305 292 4 0 0 4 [[183, 456]] 1.0 6o8u Homo sapiens TKL_IRAK4_HUMAN TKL 4.3e-84 288.1 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O8UD Q9NWZ3 162 458 460.0 LS7:501 Type1 Inactive DFGin 6.686 13.956 BLAminus -123.57, 176.25 66.06, 85.61 -109.09, 18.14 308.14, 93.15 -62.5, -37.48 in-out in 9.039 Saltbr-out 4.98 HRD-in -73.18, -49.75 72.94, 10.03 out-in-in SNCoii in-in ActLoopNT-in 2.847 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.37, 151.31 APE9-dihe-na 137.68, -175.61 APE8-dihe-in -104.71, 113.88 APE8-rot-in 306.99 APE67-dihe-in -63.19, -22.97 -60.18, -27.94 APE12-dist-in 9.959 APE11-dist-in 11.834 APE10-dist-in 6.908 APE9-dist-in 4.658 None TPO345,SEP346 TPO345,SEP346 XRAY 1.8 0.232 0.255 D 305 290 7 0 0 6 [[183, 456]] 1.0 6o8u Homo sapiens TKL_IRAK4_HUMAN TKL 4.3e-84 288.1 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 6O8U — TKL IRAK4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name