PDB: 6NZP — TYR TYK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 6NZPB

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR TYK2-1 TYK2_HUMAN 6NZPA P29597 580 869 1187.0 LB7:901 Type1 Pseudo DFGin 7.454 12.358 None -74.98, 168.42 -62.51, 146.95 -73.8, -0.03 29.8, 144.9 77.36, -162.45 in-na in 9.2156 Saltbr-na 999.0 HRD-in -77.18, -62.62 87.16, 3.67 na-out-out SNCaoo out-out ActLoopNT-out 8.3072 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -55.98, -44.81 APE9-dihe-out -54.69, -25.84 APE8-dihe-out -83.74, 2.24 APE8-rot-na 279.61 APE67-dihe-out -91.79, -3.26 -74.14, 129.81 APE12-dist-na 9.758 APE11-dist-na 11.986 APE10-dist-na 16.1538 APE9-dist-out 11.5549 None None None XRAY 2.35 0.191 0.238 A 317.0 259.0 31 24 24 0 [[589, 868], [897, 1171]] 2.0 6nzp TYR_TYK2-1_HUMAN TYR 5.4e-60 208.9 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 6NZPB P29597 580 868 1187.0 LB7:901 Type1 Pseudo DFGin 7.4573 12.3775 None -74.39, 168.01 -61.52, 147.56 -74.66, 0.45 29.5, 145.4 75.25, -161.58 in-na in 9.2883 Saltbr-na 999.0 HRD-in -77.4, -62.3 87.31, 3.57 na-out-out SNCaoo out-out ActLoopNT-out 8.2471 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -56.49, -45.45 APE9-dihe-out -54.3, -24.89 APE8-dihe-out -83.35, -4.08 APE8-rot-na 280.62 APE67-dihe-out -91.28, -1.02 -71.12, 130.29 APE12-dist-na 9.7731 APE11-dist-na 12.02 APE10-dist-na 16.2103 APE9-dist-out 11.5561 None None None XRAY 2.35 0.191 0.238 B 317.0 260.0 29 24 24 0 [[589, 868], [897, 1171]] 2.0 6nzp TYR_TYK2-1_HUMAN TYR 5.4e-60 208.9 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2

PDB: 6NZP — TYR TYK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 6NZPB

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR TYK2-1 TYK2_HUMAN 6NZPA P29597 580 869 1187.0 LB7:901 Type1 Pseudo DFGin 7.454 12.358 None -74.98, 168.42 -62.51, 146.95 -73.8, -0.03 29.8, 144.9 77.36, -162.45 in-na in 9.2156 Saltbr-na 999.0 HRD-in -77.18, -62.62 87.16, 3.67 na-out-out SNCaoo out-out ActLoopNT-out 8.3072 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -55.98, -44.81 APE9-dihe-out -54.69, -25.84 APE8-dihe-out -83.74, 2.24 APE8-rot-na 279.61 APE67-dihe-out -91.79, -3.26 -74.14, 129.81 APE12-dist-na 9.758 APE11-dist-na 11.986 APE10-dist-na 16.1538 APE9-dist-out 11.5549 None None None XRAY 2.35 0.191 0.238 A 317.0 259.0 31 24 24 0 [[589, 868], [897, 1171]] 2.0 6nzp Homo sapiens TYR_TYK2-1_HUMAN TYR 5.4e-60 208.9 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 6NZPB P29597 580 868 1187.0 LB7:901 Type1 Pseudo DFGin 7.4573 12.3775 None -74.39, 168.01 -61.52, 147.56 -74.66, 0.45 29.5, 145.4 75.25, -161.58 in-na in 9.2883 Saltbr-na 999.0 HRD-in -77.4, -62.3 87.31, 3.57 na-out-out SNCaoo out-out ActLoopNT-out 8.2471 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -56.49, -45.45 APE9-dihe-out -54.3, -24.89 APE8-dihe-out -83.35, -4.08 APE8-rot-na 280.62 APE67-dihe-out -91.28, -1.02 -71.12, 130.29 APE12-dist-na 9.7731 APE11-dist-na 12.02 APE10-dist-na 16.2103 APE9-dist-out 11.5561 None None None XRAY 2.35 0.191 0.238 B 317.0 260.0 29 24 24 0 [[589, 868], [897, 1171]] 2.0 6nzp Homo sapiens TYR_TYK2-1_HUMAN TYR 5.4e-60 208.9 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2

PDB: 6NZP — TYR TYK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name