| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | BTK | BTK_HUMAN | 6NZMA | Q06187 | 395 | 659 | 659.0 | L9S:701 | Type1 | Inactive | DFGin | 6.1954 | 13.4061 | BLBplus | -127.43, 159.91 | 61.39, 26.55 | -69.03, 132.98 | 44.91, 93.72 | 80.46, -12.65 | out-none | out | 14.3945 | Saltbr-none | 999.0 | HRD-in | -68.73, -54.84 | 83.57, -10.4 | none-out-out | SNCnoo | out-out | ActLoopNT-out | 8.1073 | ActLoopCT-out | TYR | APEdihe_oiiai | APEdist_aaao | APE10-dihe-out | -121.71, 16.48 | APE9-dihe-in | -71.64, 143.15 | APE8-dihe-in | -80.68, 63.75 | APE8-rot-na | 25.92 | APE67-dihe-in | -79.55, -7.2 | -50.65, -39.49 | APE12-dist-na | 17.0531 | APE11-dist-na | 19.2307 | APE10-dist-na | 14.512 | APE9-dist-out | 8.7338 | None | None | None | XRAY | 1.72 | 0.179 | 0.248 | A | 280.0 | 263.0 | 2 | 29 | 29 | 0 | [[402, 653]] | 1.0 | 6nzm | TYR_BTK_HUMAN | TYR | 6.8e-93 | 316.7 | 1.0 | 258.0 | 258.0 | 538 | 539 | 540 | 542 | 544 | 430 | 445 | 449 | 518 | 520 | 519 | 521.0 | 579 | 567 | 562 | 561 | 560 | 559 | 558 | 557 | 556 | 475 | Tyrosine-protein kinase BTK |
| TYR | BTK | BTK_HUMAN | 6NZMD | Q06187 | 395 | 659 | 659.0 | L9S:701 | Type1 | Inactive | DFGin | 6.4985 | 13.2753 | BLBplus | -122.27, 161.21 | 59.21, 28.98 | -64.38, 134.47 | 41.01, 97.39 | 85.68, -23.76 | out-none | out | 14.1566 | Saltbr-none | 999.0 | HRD-in | -71.79, -59.45 | 78.27, -11.98 | none-out-out | SNCnoo | out-out | ActLoopNT-out | 8.112 | ActLoopCT-out | TYR | APEdihe_oiiai | APEdist_aaao | APE10-dihe-out | -112.69, 14.7 | APE9-dihe-in | -72.11, 142.63 | APE8-dihe-in | -71.57, 65.61 | APE8-rot-na | 26.12 | APE67-dihe-in | -72.16, -8.93 | -55.34, -48.1 | APE12-dist-na | 17.0086 | APE11-dist-na | 19.3322 | APE10-dist-na | 14.4792 | APE9-dist-out | 8.5308 | None | None | None | XRAY | 1.72 | 0.179 | 0.248 | D | 280.0 | 264.0 | 1 | 29 | 29 | 0 | [[402, 653]] | 1.0 | 6nzm | TYR_BTK_HUMAN | TYR | 6.8e-93 | 316.7 | 1.0 | 258.0 | 258.0 | 538 | 539 | 540 | 542 | 544 | 430 | 445 | 449 | 518 | 520 | 519 | 521.0 | 579 | 567 | 562 | 561 | 560 | 559 | 558 | 557 | 556 | 475 | Tyrosine-protein kinase BTK |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | BTK | BTK_HUMAN | 6NZMA | Q06187 | 395 | 659 | 659.0 | L9S:701 | Type1 | Inactive | DFGin | 6.1954 | 13.4061 | BLBplus | -127.43, 159.91 | 61.39, 26.55 | -69.03, 132.98 | 44.91, 93.72 | 80.46, -12.65 | out-none | out | 14.3945 | Saltbr-none | 999.0 | HRD-in | -68.73, -54.84 | 83.57, -10.4 | none-out-out | SNCnoo | out-out | ActLoopNT-out | 8.1073 | ActLoopCT-out | TYR | APEdihe_oiiai | APEdist_aaao | APE10-dihe-out | -121.71, 16.48 | APE9-dihe-in | -71.64, 143.15 | APE8-dihe-in | -80.68, 63.75 | APE8-rot-na | 25.92 | APE67-dihe-in | -79.55, -7.2 | -50.65, -39.49 | APE12-dist-na | 17.0531 | APE11-dist-na | 19.2307 | APE10-dist-na | 14.512 | APE9-dist-out | 8.7338 | None | None | None | XRAY | 1.72 | 0.179 | 0.248 | A | 280.0 | 263.0 | 2 | 29 | 29 | 0 | [[402, 653]] | 1.0 | 6nzm | Homo sapiens | TYR_BTK_HUMAN | TYR | 6.8e-93 | 316.7 | 1.0 | 258.0 | 258.0 | 538 | 539 | 540 | 542 | 544 | 430 | 445 | 449 | 518 | 520 | 519 | 521.0 | 579 | 567 | 562 | 561 | 560 | 559 | 558 | 557 | 556 | 475 | Tyrosine-protein kinase BTK |
| TYR | BTK | BTK_HUMAN | 6NZMD | Q06187 | 395 | 659 | 659.0 | L9S:701 | Type1 | Inactive | DFGin | 6.4985 | 13.2753 | BLBplus | -122.27, 161.21 | 59.21, 28.98 | -64.38, 134.47 | 41.01, 97.39 | 85.68, -23.76 | out-none | out | 14.1566 | Saltbr-none | 999.0 | HRD-in | -71.79, -59.45 | 78.27, -11.98 | none-out-out | SNCnoo | out-out | ActLoopNT-out | 8.112 | ActLoopCT-out | TYR | APEdihe_oiiai | APEdist_aaao | APE10-dihe-out | -112.69, 14.7 | APE9-dihe-in | -72.11, 142.63 | APE8-dihe-in | -71.57, 65.61 | APE8-rot-na | 26.12 | APE67-dihe-in | -72.16, -8.93 | -55.34, -48.1 | APE12-dist-na | 17.0086 | APE11-dist-na | 19.3322 | APE10-dist-na | 14.4792 | APE9-dist-out | 8.5308 | None | None | None | XRAY | 1.72 | 0.179 | 0.248 | D | 280.0 | 264.0 | 1 | 29 | 29 | 0 | [[402, 653]] | 1.0 | 6nzm | Homo sapiens | TYR_BTK_HUMAN | TYR | 6.8e-93 | 316.7 | 1.0 | 258.0 | 258.0 | 538 | 539 | 540 | 542 | 544 | 430 | 445 | 449 | 518 | 520 | 519 | 521.0 | 579 | 567 | 562 | 561 | 560 | 559 | 558 | 557 | 556 | 475 | Tyrosine-protein kinase BTK |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|