PDB: 6NZH — TYR TYK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 6NZHA

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR TYK2-1 TYK2_HUMAN 6NZHA P29597 581 866 1187.0 L9A:4000 Type1 Pseudo DFGin 7.4056 12.7716 None -62.74, 170.7 -72.48, 150.15 -70.83, -2.83 23.35, 152.01 73.55, -152.26 in-na in 9.497 Saltbr-na 999.0 HRD-in -83.24, -60.86 86.7, -4.43 na-out-out SNCaoo out-out ActLoopNT-out 8.387 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -64.05, -35.12 APE9-dihe-out -65.62, -29.8 APE8-dihe-out -77.88, -5.55 APE8-rot-na 294.99 APE67-dihe-out -89.76, 4.67 -72.08, 133.72 APE12-dist-na 9.7747 APE11-dist-na 12.2293 APE10-dist-na 16.4702 APE9-dist-out 11.3169 None None None XRAY 2.73 0.193 0.215 A 317.0 249.0 39 24 24 0 [[589, 868], [897, 1171]] 2.0 6nzh TYR_TYK2-1_HUMAN TYR 5.4e-60 208.9 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 6NZHB P29597 580 867 1187.0 L9A:4000 Type1 Pseudo DFGin 7.436 12.5992 None -60.73, 169.6 -71.23, 150.14 -70.46, -1.47 23.31, 151.91 71.77, -152.11 in-na in 9.3762 Saltbr-na 999.0 HRD-in -83.11, -60.28 86.79, -5.89 na-out-out SNCaoo out-out ActLoopNT-out 8.3079 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -64.38, -35.33 APE9-dihe-out -65.44, -29.63 APE8-dihe-out -78.49, -5.17 APE8-rot-na 295.66 APE67-dihe-out -89.42, 4.66 -71.76, 134.2 APE12-dist-na 9.7352 APE11-dist-na 12.2156 APE10-dist-na 16.4369 APE9-dist-out 11.2686 None None None XRAY 2.73 0.193 0.215 B 317.0 249.0 40 24 24 0 [[589, 868], [897, 1171]] 2.0 6nzh TYR_TYK2-1_HUMAN TYR 5.4e-60 208.9 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2

PDB: 6NZH — TYR TYK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 6NZHA

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR TYK2-1 TYK2_HUMAN 6NZHA P29597 581 866 1187.0 L9A:4000 Type1 Pseudo DFGin 7.4056 12.7716 None -62.74, 170.7 -72.48, 150.15 -70.83, -2.83 23.35, 152.01 73.55, -152.26 in-na in 9.497 Saltbr-na 999.0 HRD-in -83.24, -60.86 86.7, -4.43 na-out-out SNCaoo out-out ActLoopNT-out 8.387 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -64.05, -35.12 APE9-dihe-out -65.62, -29.8 APE8-dihe-out -77.88, -5.55 APE8-rot-na 294.99 APE67-dihe-out -89.76, 4.67 -72.08, 133.72 APE12-dist-na 9.7747 APE11-dist-na 12.2293 APE10-dist-na 16.4702 APE9-dist-out 11.3169 None None None XRAY 2.73 0.193 0.215 A 317.0 249.0 39 24 24 0 [[589, 868], [897, 1171]] 2.0 6nzh Homo sapiens TYR_TYK2-1_HUMAN TYR 5.4e-60 208.9 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 6NZHB P29597 580 867 1187.0 L9A:4000 Type1 Pseudo DFGin 7.436 12.5992 None -60.73, 169.6 -71.23, 150.14 -70.46, -1.47 23.31, 151.91 71.77, -152.11 in-na in 9.3762 Saltbr-na 999.0 HRD-in -83.11, -60.28 86.79, -5.89 na-out-out SNCaoo out-out ActLoopNT-out 8.3079 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -64.38, -35.33 APE9-dihe-out -65.44, -29.63 APE8-dihe-out -78.49, -5.17 APE8-rot-na 295.66 APE67-dihe-out -89.42, 4.66 -71.76, 134.2 APE12-dist-na 9.7352 APE11-dist-na 12.2156 APE10-dist-na 16.4369 APE9-dist-out 11.2686 None None None XRAY 2.73 0.193 0.215 B 317.0 249.0 40 24 24 0 [[589, 868], [897, 1171]] 2.0 6nzh Homo sapiens TYR_TYK2-1_HUMAN TYR 5.4e-60 208.9 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2

PDB: 6NZH — TYR TYK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name