PDB: 6NZF — TYR TYK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 6NZFB

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR TYK2-1 TYK2_HUMAN 6NZFA P29597 580 865 1187.0 L91:901 Type1 Pseudo DFGin 7.5997 12.6706 None -71.29, 168.26 -64.87, 155.03 -75.86, -3.47 25.03, 153.09 77.38, -149.91 in-na in 9.4012 Saltbr-na 999.0 HRD-in -80.34, -62.67 82.96, 5.24 na-out-out SNCaoo out-out ActLoopNT-out 8.0939 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -65.48, -39.01 APE9-dihe-out -62.83, -25.44 APE8-dihe-out -82.23, -7.85 APE8-rot-na 215.68 APE67-dihe-out -92.43, 5.04 -68.27, 132.64 APE12-dist-na 9.8083 APE11-dist-na 12.2624 APE10-dist-na 16.5169 APE9-dist-out 11.6235 None None None XRAY 2.39 0.205 0.231 A 317.0 247.0 42 24 24 0 [[589, 868], [897, 1171]] 2.0 6nzf TYR_TYK2-1_HUMAN TYR 5.4e-60 208.9 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 6NZFB P29597 580 867 1187.0 L91:901 Type1 Pseudo DFGin 7.6703 12.5979 None -70.84, 168.4 -64.97, 153.82 -75.67, -2.7 25.33, 152.34 77.04, -149.81 in-na in 9.3721 Saltbr-na 999.0 HRD-in -81.43, -61.17 83.19, 3.8 na-out-out SNCaoo out-out ActLoopNT-out 8.1122 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -65.59, -38.89 APE9-dihe-out -62.81, -25.28 APE8-dihe-out -84.37, -2.23 APE8-rot-na 213.59 APE67-dihe-out -91.99, 5.73 -72.88, 133.85 APE12-dist-na 9.7519 APE11-dist-na 12.2295 APE10-dist-na 16.478 APE9-dist-out 11.5547 None None None XRAY 2.39 0.205 0.231 B 317.0 248.0 41 24 24 0 [[589, 868], [897, 1171]] 2.0 6nzf TYR_TYK2-1_HUMAN TYR 5.4e-60 208.9 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2

PDB: 6NZF — TYR TYK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 6NZFB

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR TYK2-1 TYK2_HUMAN 6NZFA P29597 580 865 1187.0 L91:901 Type1 Pseudo DFGin 7.5997 12.6706 None -71.29, 168.26 -64.87, 155.03 -75.86, -3.47 25.03, 153.09 77.38, -149.91 in-na in 9.4012 Saltbr-na 999.0 HRD-in -80.34, -62.67 82.96, 5.24 na-out-out SNCaoo out-out ActLoopNT-out 8.0939 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -65.48, -39.01 APE9-dihe-out -62.83, -25.44 APE8-dihe-out -82.23, -7.85 APE8-rot-na 215.68 APE67-dihe-out -92.43, 5.04 -68.27, 132.64 APE12-dist-na 9.8083 APE11-dist-na 12.2624 APE10-dist-na 16.5169 APE9-dist-out 11.6235 None None None XRAY 2.39 0.205 0.231 A 317.0 247.0 42 24 24 0 [[589, 868], [897, 1171]] 2.0 6nzf Homo sapiens TYR_TYK2-1_HUMAN TYR 5.4e-60 208.9 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 6NZFB P29597 580 867 1187.0 L91:901 Type1 Pseudo DFGin 7.6703 12.5979 None -70.84, 168.4 -64.97, 153.82 -75.67, -2.7 25.33, 152.34 77.04, -149.81 in-na in 9.3721 Saltbr-na 999.0 HRD-in -81.43, -61.17 83.19, 3.8 na-out-out SNCaoo out-out ActLoopNT-out 8.1122 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -65.59, -38.89 APE9-dihe-out -62.81, -25.28 APE8-dihe-out -84.37, -2.23 APE8-rot-na 213.59 APE67-dihe-out -91.99, 5.73 -72.88, 133.85 APE12-dist-na 9.7519 APE11-dist-na 12.2295 APE10-dist-na 16.478 APE9-dist-out 11.5547 None None None XRAY 2.39 0.205 0.231 B 317.0 248.0 41 24 24 0 [[589, 868], [897, 1171]] 2.0 6nzf Homo sapiens TYR_TYK2-1_HUMAN TYR 5.4e-60 208.9 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2

PDB: 6NZF — TYR TYK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name