PDB: 6NSL — TYR TYK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 6NSLA

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR TYK2-1 TYK2_HUMAN 6NSLA P29597 581 866 1187.0 KZJ:901 Type1 Pseudo DFGin 7.4466 12.6266 None -65.67, 163.1 -59.9, 147.3 -72.43, 0.95 25.4, 149.24 71.0, -150.31 in-na in 9.4495 Saltbr-na 999.0 HRD-in -79.19, -61.15 86.61, -0.76 na-out-out SNCaoo out-out ActLoopNT-out 8.317 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -66.34, -39.28 APE9-dihe-out -63.02, -22.39 APE8-dihe-out -82.22, -10.35 APE8-rot-na 292.93 APE67-dihe-out -91.53, -2.04 -67.32, 133.05 APE12-dist-na 9.7215 APE11-dist-na 12.197 APE10-dist-na 16.4126 APE9-dist-out 11.6997 None None None XRAY 2.15 0.203 0.213 A 317.0 251.0 37 24 24 0 [[589, 868], [897, 1171]] 2.0 6nsl TYR_TYK2-1_HUMAN TYR 5.4e-60 208.9 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 6NSLB P29597 581 867 1187.0 KZJ:901 Type1 Pseudo DFGin 7.4662 12.5425 None -65.53, 162.68 -58.2, 146.74 -72.38, 1.37 25.74, 148.82 71.06, -152.3 in-na in 9.4228 Saltbr-na 999.0 HRD-in -80.39, -61.97 87.32, -2.61 na-out-out SNCaoo out-out ActLoopNT-out 8.2412 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -66.57, -38.38 APE9-dihe-out -63.64, -23.52 APE8-dihe-out -84.88, -4.11 APE8-rot-na 200.51 APE67-dihe-out -91.36, -1.36 -71.83, 133.14 APE12-dist-na 9.6668 APE11-dist-na 12.1774 APE10-dist-na 16.3911 APE9-dist-out 11.5683 None None None XRAY 2.15 0.203 0.213 B 317.0 248.0 40 24 24 0 [[589, 868], [897, 1171]] 2.0 6nsl TYR_TYK2-1_HUMAN TYR 5.4e-60 208.9 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2

PDB: 6NSL — TYR TYK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 6NSLA

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR TYK2-1 TYK2_HUMAN 6NSLA P29597 581 866 1187.0 KZJ:901 Type1 Pseudo DFGin 7.4466 12.6266 None -65.67, 163.1 -59.9, 147.3 -72.43, 0.95 25.4, 149.24 71.0, -150.31 in-na in 9.4495 Saltbr-na 999.0 HRD-in -79.19, -61.15 86.61, -0.76 na-out-out SNCaoo out-out ActLoopNT-out 8.317 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -66.34, -39.28 APE9-dihe-out -63.02, -22.39 APE8-dihe-out -82.22, -10.35 APE8-rot-na 292.93 APE67-dihe-out -91.53, -2.04 -67.32, 133.05 APE12-dist-na 9.7215 APE11-dist-na 12.197 APE10-dist-na 16.4126 APE9-dist-out 11.6997 None None None XRAY 2.15 0.203 0.213 A 317.0 251.0 37 24 24 0 [[589, 868], [897, 1171]] 2.0 6nsl Homo sapiens TYR_TYK2-1_HUMAN TYR 5.4e-60 208.9 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 6NSLB P29597 581 867 1187.0 KZJ:901 Type1 Pseudo DFGin 7.4662 12.5425 None -65.53, 162.68 -58.2, 146.74 -72.38, 1.37 25.74, 148.82 71.06, -152.3 in-na in 9.4228 Saltbr-na 999.0 HRD-in -80.39, -61.97 87.32, -2.61 na-out-out SNCaoo out-out ActLoopNT-out 8.2412 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -66.57, -38.38 APE9-dihe-out -63.64, -23.52 APE8-dihe-out -84.88, -4.11 APE8-rot-na 200.51 APE67-dihe-out -91.36, -1.36 -71.83, 133.14 APE12-dist-na 9.6668 APE11-dist-na 12.1774 APE10-dist-na 16.3911 APE9-dist-out 11.5683 None None None XRAY 2.15 0.203 0.213 B 317.0 248.0 40 24 24 0 [[589, 868], [897, 1171]] 2.0 6nsl Homo sapiens TYR_TYK2-1_HUMAN TYR 5.4e-60 208.9 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2

PDB: 6NSL — TYR TYK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name