PDB: 6G3C — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 6G3CA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-1 JAK2_HUMAN 6G3CA O60674 537 808 1132.0 EKT:901 Type1 Pseudo DFGin 7.9293 13.2972 None -92.88, -174.23 -74.55, 160.0 -77.81, -9.76 27.51, 143.79 70.13, -167.0 in-na in 9.4623 Saltbr-na 999.0 HRD-in -89.47, -61.45 91.27, -4.79 na-out-out SNCaoo out-out ActLoopNT-out 9.753 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -65.76, -39.79 APE9-dihe-out -61.91, -29.13 APE8-dihe-out -80.12, 0.2 APE8-rot-na 289.19 APE67-dihe-out -101.75, 22.48 -69.62, 136.72 APE12-dist-na 9.7666 APE11-dist-na 11.5665 APE10-dist-na 16.1545 APE9-dist-out 12.7021 W659A,W777A,F794H None None XRAY 1.6 0.196 0.22 A 272.0 272.0 0 24 24 0 [[545, 807], [849, 1125]] 2.0 6g3c TYR_JAK2-1_HUMAN TYR 2.9e-64 222.8 2.0 260.0 259.0 698 699 700 702 704 581 597 601 670 672 671 673.0 735 722 717 716 715 714 713 712 711 627 Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6G3CB O60674 537 808 1132.0 EKT:901 Type1 Pseudo DFGin 7.9902 13.415 None -91.77, -175.11 -73.45, 159.45 -76.52, -11.86 28.49, 143.52 73.41, -164.04 in-na in 9.643 Saltbr-na 999.0 HRD-in -89.94, -61.82 90.1, -3.95 na-out-out SNCaoo out-out ActLoopNT-out 9.6929 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -67.88, -39.41 APE9-dihe-out -62.88, -28.18 APE8-dihe-out -81.21, 1.24 APE8-rot-na 288.18 APE67-dihe-out -102.69, 23.29 -70.43, 136.03 APE12-dist-na 9.7694 APE11-dist-na 11.5802 APE10-dist-na 16.1381 APE9-dist-out 12.6902 W659A,W777A,F794H None None XRAY 1.6 0.196 0.22 B 272.0 268.0 4 24 24 0 [[545, 807], [849, 1125]] 2.0 6g3c TYR_JAK2-1_HUMAN TYR 2.9e-64 222.8 2.0 260.0 259.0 698 699 700 702 704 581 597 601 670 672 671 673.0 735 722 717 716 715 714 713 712 711 627 Tyrosine-protein kinase JAK2

PDB: 6G3C — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 6G3CA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-1 JAK2_HUMAN 6G3CA O60674 537 808 1132.0 EKT:901 Type1 Pseudo DFGin 7.9293 13.2972 None -92.88, -174.23 -74.55, 160.0 -77.81, -9.76 27.51, 143.79 70.13, -167.0 in-na in 9.4623 Saltbr-na 999.0 HRD-in -89.47, -61.45 91.27, -4.79 na-out-out SNCaoo out-out ActLoopNT-out 9.753 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -65.76, -39.79 APE9-dihe-out -61.91, -29.13 APE8-dihe-out -80.12, 0.2 APE8-rot-na 289.19 APE67-dihe-out -101.75, 22.48 -69.62, 136.72 APE12-dist-na 9.7666 APE11-dist-na 11.5665 APE10-dist-na 16.1545 APE9-dist-out 12.7021 W659A,W777A,F794H None None XRAY 1.6 0.196 0.22 A 272.0 272.0 0 24 24 0 [[545, 807], [849, 1125]] 2.0 6g3c Homo sapiens TYR_JAK2-1_HUMAN TYR 2.9e-64 222.8 2.0 260.0 259.0 698 699 700 702 704 581 597 601 670 672 671 673.0 735 722 717 716 715 714 713 712 711 627 Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6G3CB O60674 537 808 1132.0 EKT:901 Type1 Pseudo DFGin 7.9902 13.415 None -91.77, -175.11 -73.45, 159.45 -76.52, -11.86 28.49, 143.52 73.41, -164.04 in-na in 9.643 Saltbr-na 999.0 HRD-in -89.94, -61.82 90.1, -3.95 na-out-out SNCaoo out-out ActLoopNT-out 9.6929 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -67.88, -39.41 APE9-dihe-out -62.88, -28.18 APE8-dihe-out -81.21, 1.24 APE8-rot-na 288.18 APE67-dihe-out -102.69, 23.29 -70.43, 136.03 APE12-dist-na 9.7694 APE11-dist-na 11.5802 APE10-dist-na 16.1381 APE9-dist-out 12.6902 W659A,W777A,F794H None None XRAY 1.6 0.196 0.22 B 272.0 268.0 4 24 24 0 [[545, 807], [849, 1125]] 2.0 6g3c Homo sapiens TYR_JAK2-1_HUMAN TYR 2.9e-64 222.8 2.0 260.0 259.0 698 699 700 702 704 581 597 601 670 672 671 673.0 735 722 717 716 715 714 713 712 711 627 Tyrosine-protein kinase JAK2

PDB: 6G3C — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name