PDB: 6FAD — CMGC SRPK1_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6FADC
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC SRPK1 SRPK1_HUMAN 6FADA Q96SB4 55 655 655.0 No_ligand No_ligand Inactive DFGin 6.22 15.136 BLAminus -122.93, 179.12 57.38, 61.42 -78.03, 19.0 277.69, 78.02 -68.08, -18.77 in-out in 9.929 Saltbr-out 5.699 HRD-in -65.55, -50.38 76.6, 9.52 out-in-out SNCoio in-out ActLoopNT-in 3.046 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -121.2, 171.46 APE9-dihe-na 71.78, 143.02 APE8-dihe-in -86.05, 154.67 APE8-rot-out 81.2 APE67-dihe-in -62.54, -19.42 -41.68, -58.38 APE12-dist-in 12.82 APE11-dist-in 10.988 APE10-dist-in 7.672 APE9-dist-in 3.138 None None None XRAY 2.801 0.201 0.257 A 618 356 245 0 0 0 [[80, 653]] 1.0 6fad CMGC_SRPK1_HUMAN CMGC 1.7e-138 466.8 1 301 301 496 497 498 500 502 109 124 128 210 212 211 213 533 521 516 515 514 513 512 511 510 166 SRSF protein kinase 1
CMGC SRPK1 SRPK1_HUMAN 6FADB Q96SB4 55 655 655.0 No_ligand No_ligand Inactive DFGin 6.232 14.986 BLAminus -113.6, 174.2 60.21, 87.3 -102.47, 28.18 286.78, 61.47 -69.13, -15.83 in-out in 9.748 Saltbr-out 4.624 HRD-in -75.61, -45.96 73.19, 8.23 out-in-out SNCoio in-out ActLoopNT-in 2.88 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -125.25, 164.85 APE9-dihe-na 73.22, 157.16 APE8-dihe-in -99.01, 141.77 APE8-rot-out 60.06 APE67-dihe-in -66.35, -13.73 -20.25, -68.69 APE12-dist-in 12.617 APE11-dist-in 10.907 APE10-dist-in 7.75 APE9-dist-in 3.18 None None None XRAY 2.801 0.201 0.257 B 618 356 245 0 0 0 [[80, 653]] 1.0 6fad CMGC_SRPK1_HUMAN CMGC 1.7e-138 466.8 1 301 301 496 497 498 500 502 109 124 128 210 212 211 213 533 521 516 515 514 513 512 511 510 166 SRSF protein kinase 1
CMGC SRPK1 SRPK1_HUMAN 6FADC Q96SB4 55 655 655.0 No_ligand No_ligand Inactive DFGin 6.517 15.295 BLAminus -123.52, -178.15 55.08, 85.74 -104.19, 20.56 276.3, 81.28 -67.88, -18.36 in-out in 9.967 Saltbr-out 5.558 HRD-in -74.58, -44.68 71.07, 8.29 out-in-in SNCoii in-in ActLoopNT-in 2.785 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -123.77, 164.16 APE9-dihe-na 77.72, 151.02 APE8-dihe-in -86.55, 133.38 APE8-rot-in 273.9 APE67-dihe-in -62.07, -14.6 -22.9, -73.33 APE12-dist-in 12.691 APE11-dist-in 10.719 APE10-dist-in 7.639 APE9-dist-in 3.236 None None None XRAY 2.801 0.201 0.257 C 618 359 242 0 0 0 [[80, 653]] 1.0 6fad CMGC_SRPK1_HUMAN CMGC 1.7e-138 466.8 1 301 301 496 497 498 500 502 109 124 128 210 212 211 213 533 521 516 515 514 513 512 511 510 166 SRSF protein kinase 1
CMGC SRPK1 SRPK1_HUMAN 6FADD Q96SB4 55 655 655.0 No_ligand No_ligand Inactive DFGin 6.377 15.33 BLAminus -119.7, -178.47 48.47, 81.81 -91.0, 13.61 274.63, 34.06 -64.49, -20.18 out-out out 10.194 Saltbr-out 5.179 HRD-in -73.88, -47.0 76.16, 9.55 out-in-in SNCoii in-in ActLoopNT-in 2.856 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -123.69, 159.48 APE9-dihe-na 80.31, 146.18 APE8-dihe-in -75.32, 143.12 APE8-rot-in 297.81 APE67-dihe-in -63.2, -18.62 -40.87, -60.1 APE12-dist-in 12.786 APE11-dist-in 10.624 APE10-dist-in 7.756 APE9-dist-in 3.164 None None None XRAY 2.801 0.201 0.257 D 618 356 245 0 0 0 [[80, 653]] 1.0 6fad CMGC_SRPK1_HUMAN CMGC 1.7e-138 466.8 1 301 301 496 497 498 500 502 109 124 128 210 212 211 213 533 521 516 515 514 513 512 511 510 166 SRSF protein kinase 1

PDB: 6FAD — CMGC SRPK1_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6FADC
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC SRPK1 SRPK1_HUMAN 6FADA Q96SB4 55 655 655.0 No_ligand No_ligand Inactive DFGin 6.22 15.136 BLAminus -122.93, 179.12 57.38, 61.42 -78.03, 19.0 277.69, 78.02 -68.08, -18.77 in-out in 9.929 Saltbr-out 5.699 HRD-in -65.55, -50.38 76.6, 9.52 out-in-out SNCoio in-out ActLoopNT-in 3.046 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -121.2, 171.46 APE9-dihe-na 71.78, 143.02 APE8-dihe-in -86.05, 154.67 APE8-rot-out 81.2 APE67-dihe-in -62.54, -19.42 -41.68, -58.38 APE12-dist-in 12.82 APE11-dist-in 10.988 APE10-dist-in 7.672 APE9-dist-in 3.138 None None None XRAY 2.801 0.201 0.257 A 618 356 245 0 0 0 [[80, 653]] 1.0 6fad Homo sapiens CMGC_SRPK1_HUMAN CMGC 1.7e-138 466.8 1 301 301 496 497 498 500 502 109 124 128 210 212 211 213 533 521 516 515 514 513 512 511 510 166 SRSF protein kinase 1
CMGC SRPK1 SRPK1_HUMAN 6FADB Q96SB4 55 655 655.0 No_ligand No_ligand Inactive DFGin 6.232 14.986 BLAminus -113.6, 174.2 60.21, 87.3 -102.47, 28.18 286.78, 61.47 -69.13, -15.83 in-out in 9.748 Saltbr-out 4.624 HRD-in -75.61, -45.96 73.19, 8.23 out-in-out SNCoio in-out ActLoopNT-in 2.88 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -125.25, 164.85 APE9-dihe-na 73.22, 157.16 APE8-dihe-in -99.01, 141.77 APE8-rot-out 60.06 APE67-dihe-in -66.35, -13.73 -20.25, -68.69 APE12-dist-in 12.617 APE11-dist-in 10.907 APE10-dist-in 7.75 APE9-dist-in 3.18 None None None XRAY 2.801 0.201 0.257 B 618 356 245 0 0 0 [[80, 653]] 1.0 6fad Homo sapiens CMGC_SRPK1_HUMAN CMGC 1.7e-138 466.8 1 301 301 496 497 498 500 502 109 124 128 210 212 211 213 533 521 516 515 514 513 512 511 510 166 SRSF protein kinase 1
CMGC SRPK1 SRPK1_HUMAN 6FADC Q96SB4 55 655 655.0 No_ligand No_ligand Inactive DFGin 6.517 15.295 BLAminus -123.52, -178.15 55.08, 85.74 -104.19, 20.56 276.3, 81.28 -67.88, -18.36 in-out in 9.967 Saltbr-out 5.558 HRD-in -74.58, -44.68 71.07, 8.29 out-in-in SNCoii in-in ActLoopNT-in 2.785 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -123.77, 164.16 APE9-dihe-na 77.72, 151.02 APE8-dihe-in -86.55, 133.38 APE8-rot-in 273.9 APE67-dihe-in -62.07, -14.6 -22.9, -73.33 APE12-dist-in 12.691 APE11-dist-in 10.719 APE10-dist-in 7.639 APE9-dist-in 3.236 None None None XRAY 2.801 0.201 0.257 C 618 359 242 0 0 0 [[80, 653]] 1.0 6fad Homo sapiens CMGC_SRPK1_HUMAN CMGC 1.7e-138 466.8 1 301 301 496 497 498 500 502 109 124 128 210 212 211 213 533 521 516 515 514 513 512 511 510 166 SRSF protein kinase 1
CMGC SRPK1 SRPK1_HUMAN 6FADD Q96SB4 55 655 655.0 No_ligand No_ligand Inactive DFGin 6.377 15.33 BLAminus -119.7, -178.47 48.47, 81.81 -91.0, 13.61 274.63, 34.06 -64.49, -20.18 out-out out 10.194 Saltbr-out 5.179 HRD-in -73.88, -47.0 76.16, 9.55 out-in-in SNCoii in-in ActLoopNT-in 2.856 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -123.69, 159.48 APE9-dihe-na 80.31, 146.18 APE8-dihe-in -75.32, 143.12 APE8-rot-in 297.81 APE67-dihe-in -63.2, -18.62 -40.87, -60.1 APE12-dist-in 12.786 APE11-dist-in 10.624 APE10-dist-in 7.756 APE9-dist-in 3.164 None None None XRAY 2.801 0.201 0.257 D 618 356 245 0 0 0 [[80, 653]] 1.0 6fad Homo sapiens CMGC_SRPK1_HUMAN CMGC 1.7e-138 466.8 1 301 301 496 497 498 500 502 109 124 128 210 212 211 213 533 521 516 515 514 513 512 511 510 166 SRSF protein kinase 1

PDB: 6FAD — CMGC SRPK1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name