PDB: 6DUK — TYR EGFR_HUMAN

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 6 100.0% 6DUKA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 6DUKA P00533 701 1006 1210.0 ANP:1102,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.4162 14.8008 BLBplus -133.89, 165.03 66.94, 37.08 -93.36, 166.29 58.42, 86.37 91.91, 6.11 out-out out 13.9176 Saltbr-out 14.1793 HRD-in -76.73, -64.87 85.37, -18.97 out-out-out SNCooo out-out ActLoopNT-out 7.4382 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -100.39, -10.84 APE9-dihe-in -125.5, 116.79 APE8-dihe-in -80.16, 76.04 APE8-rot-na 31.69 APE67-dihe-in -76.14, -1.34 -58.18, -44.83 APE12-dist-na 17.3641 APE11-dist-na 15.2023 APE10-dist-na 11.7763 APE9-dist-in 7.3106 T790M,V948R None None XRAY 2.2 0.191 0.223 A 331.0 306.0 0 30 30 0 [[712, 970]] 1.0 6duk TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKB P00533 699 1007 1210.0 ANP:1102,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.6806 14.6502 BLBplus -136.44, 165.42 61.83, 36.22 -89.54, 161.73 53.44, 89.67 90.48, 19.39 out-out out 13.8125 Saltbr-out 14.7331 HRD-in -68.48, -61.78 82.94, -15.18 out-out-none SNCoon out-none ActLoopNT-out 7.2922 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 128.53 APE8-dihe-in -76.17, 63.91 APE8-rot-na 26.99 APE67-dihe-in -79.83, -2.27 -51.77, -41.31 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.9222 T790M,V948R None None XRAY 2.2 0.191 0.223 B 331.0 296.0 13 30 17 13 [[712, 970]] 1.0 6duk TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKC P00533 699 1007 1210.0 ANP:1102,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.6614 14.3909 BLBplus -137.36, 170.05 61.14, 32.95 -87.42, 165.36 52.89, 84.68 86.51, 15.0 out-out out 13.7494 Saltbr-out 12.3873 HRD-in -66.04, -61.2 80.35, -9.27 out-out-none SNCoon out-none ActLoopNT-out 8.2862 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 116.92 APE8-dihe-in -77.64, 67.39 APE8-rot-na 32.93 APE67-dihe-in -71.69, -8.16 -55.72, -42.95 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.8229 T790M,V948R None None XRAY 2.2 0.191 0.223 C 331.0 295.0 14 30 16 14 [[712, 970]] 1.0 6duk TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKD P00533 701 1007 1210.0 ANP:1102,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.6052 14.6344 BLBplus -137.83, 165.45 65.63, 29.61 -82.3, 167.28 56.12, 84.13 94.16, 13.47 out-out out 14.053 Saltbr-out 14.8858 HRD-in -74.03, -57.71 81.46, -18.53 out-out-out SNCooo out-out ActLoopNT-out 7.3207 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -76.03, 11.31 APE9-dihe-in -134.89, 121.24 APE8-dihe-in -86.59, 77.19 APE8-rot-na 34.21 APE67-dihe-in -72.84, -7.51 -59.65, -43.13 APE12-dist-na 17.7472 APE11-dist-na 15.5553 APE10-dist-na 11.9033 APE9-dist-in 7.5388 T790M,V948R None None XRAY 2.2 0.191 0.223 D 331.0 307.0 0 30 30 0 [[712, 970]] 1.0 6duk TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKE P00533 698 1007 1210.0 ANP:1102,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.7057 14.387 BLBplus -132.31, 167.27 63.11, 42.82 -102.17, 159.55 52.62, 85.09 88.84, 16.78 out-out out 13.7684 Saltbr-out 14.3613 HRD-in -70.33, -59.21 85.76, -23.74 out-out-none SNCoon out-none ActLoopNT-out 7.6865 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 1.83 APE9-dihe-in -127.74, 112.92 APE8-dihe-in -68.38, 64.27 APE8-rot-na 21.48 APE67-dihe-in -73.72, -8.33 -52.7, -41.98 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 13.2913 APE9-dist-in 7.9406 T790M,V948R None None XRAY 2.2 0.191 0.223 E 331.0 298.0 12 30 18 12 [[712, 970]] 1.0 6duk TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKF P00533 701 1009 1210.0 ANP:1102,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.6528 14.6121 BLBplus -133.82, 164.75 63.96, 32.85 -83.32, 163.7 53.83, 93.49 88.31, 19.42 out-out out 14.1084 Saltbr-out 15.1439 HRD-in -67.38, -62.37 88.35, -19.9 out-out-none SNCoon out-none ActLoopNT-out 7.3188 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 115.72 APE8-dihe-in -80.72, 70.63 APE8-rot-na 32.98 APE67-dihe-in -75.6, -2.87 -62.49, -36.24 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.8407 T790M,V948R None None XRAY 2.2 0.191 0.223 F 331.0 298.0 11 30 19 11 [[712, 970]] 1.0 6duk TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 6DUK — TYR EGFR_HUMAN

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 6 100.0% 6DUKA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 6DUKA P00533 701 1006 1210.0 ANP:1102,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.4162 14.8008 BLBplus -133.89, 165.03 66.94, 37.08 -93.36, 166.29 58.42, 86.37 91.91, 6.11 out-out out 13.9176 Saltbr-out 14.1793 HRD-in -76.73, -64.87 85.37, -18.97 out-out-out SNCooo out-out ActLoopNT-out 7.4382 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -100.39, -10.84 APE9-dihe-in -125.5, 116.79 APE8-dihe-in -80.16, 76.04 APE8-rot-na 31.69 APE67-dihe-in -76.14, -1.34 -58.18, -44.83 APE12-dist-na 17.3641 APE11-dist-na 15.2023 APE10-dist-na 11.7763 APE9-dist-in 7.3106 T790M,V948R None None XRAY 2.2 0.191 0.223 A 331.0 306.0 0 30 30 0 [[712, 970]] 1.0 6duk Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKB P00533 699 1007 1210.0 ANP:1102,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.6806 14.6502 BLBplus -136.44, 165.42 61.83, 36.22 -89.54, 161.73 53.44, 89.67 90.48, 19.39 out-out out 13.8125 Saltbr-out 14.7331 HRD-in -68.48, -61.78 82.94, -15.18 out-out-none SNCoon out-none ActLoopNT-out 7.2922 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 128.53 APE8-dihe-in -76.17, 63.91 APE8-rot-na 26.99 APE67-dihe-in -79.83, -2.27 -51.77, -41.31 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.9222 T790M,V948R None None XRAY 2.2 0.191 0.223 B 331.0 296.0 13 30 17 13 [[712, 970]] 1.0 6duk Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKC P00533 699 1007 1210.0 ANP:1102,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.6614 14.3909 BLBplus -137.36, 170.05 61.14, 32.95 -87.42, 165.36 52.89, 84.68 86.51, 15.0 out-out out 13.7494 Saltbr-out 12.3873 HRD-in -66.04, -61.2 80.35, -9.27 out-out-none SNCoon out-none ActLoopNT-out 8.2862 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 116.92 APE8-dihe-in -77.64, 67.39 APE8-rot-na 32.93 APE67-dihe-in -71.69, -8.16 -55.72, -42.95 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.8229 T790M,V948R None None XRAY 2.2 0.191 0.223 C 331.0 295.0 14 30 16 14 [[712, 970]] 1.0 6duk Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKD P00533 701 1007 1210.0 ANP:1102,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.6052 14.6344 BLBplus -137.83, 165.45 65.63, 29.61 -82.3, 167.28 56.12, 84.13 94.16, 13.47 out-out out 14.053 Saltbr-out 14.8858 HRD-in -74.03, -57.71 81.46, -18.53 out-out-out SNCooo out-out ActLoopNT-out 7.3207 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -76.03, 11.31 APE9-dihe-in -134.89, 121.24 APE8-dihe-in -86.59, 77.19 APE8-rot-na 34.21 APE67-dihe-in -72.84, -7.51 -59.65, -43.13 APE12-dist-na 17.7472 APE11-dist-na 15.5553 APE10-dist-na 11.9033 APE9-dist-in 7.5388 T790M,V948R None None XRAY 2.2 0.191 0.223 D 331.0 307.0 0 30 30 0 [[712, 970]] 1.0 6duk Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKE P00533 698 1007 1210.0 ANP:1102,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.7057 14.387 BLBplus -132.31, 167.27 63.11, 42.82 -102.17, 159.55 52.62, 85.09 88.84, 16.78 out-out out 13.7684 Saltbr-out 14.3613 HRD-in -70.33, -59.21 85.76, -23.74 out-out-none SNCoon out-none ActLoopNT-out 7.6865 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 1.83 APE9-dihe-in -127.74, 112.92 APE8-dihe-in -68.38, 64.27 APE8-rot-na 21.48 APE67-dihe-in -73.72, -8.33 -52.7, -41.98 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 13.2913 APE9-dist-in 7.9406 T790M,V948R None None XRAY 2.2 0.191 0.223 E 331.0 298.0 12 30 18 12 [[712, 970]] 1.0 6duk Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKF P00533 701 1009 1210.0 ANP:1102,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.6528 14.6121 BLBplus -133.82, 164.75 63.96, 32.85 -83.32, 163.7 53.83, 93.49 88.31, 19.42 out-out out 14.1084 Saltbr-out 15.1439 HRD-in -67.38, -62.37 88.35, -19.9 out-out-none SNCoon out-none ActLoopNT-out 7.3188 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 115.72 APE8-dihe-in -80.72, 70.63 APE8-rot-na 32.98 APE67-dihe-in -75.6, -2.87 -62.49, -36.24 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.8407 T790M,V948R None None XRAY 2.2 0.191 0.223 F 331.0 298.0 11 30 19 11 [[712, 970]] 1.0 6duk Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 6DUK — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name