| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | PTK6 | PTK6_HUMAN | 6CZ2A | Q13882 | 182 | 443 | 451.0 | No_ligand | No_ligand | Inactive | DFGin | 5.3502 | 13.1432 | BLBplus | -121.1, 176.65 | 66.9, 22.32 | -67.74, 135.96 | 36.4, 96.02 | 85.0, -21.68 | out-out | out | 13.5103 | Saltbr-out | 12.6917 | HRD-in | -67.17, -59.02 | 88.03, -15.86 | out-out-out | SNCooo | out-out | ActLoopNT-out | 8.009 | ActLoopCT-out | TYR | APEdihe_oioai | APEdist_aaao | APE10-dihe-out | -114.8, 16.86 | APE9-dihe-in | -107.35, 157.15 | APE8-dihe-out | -58.54, -13.36 | APE8-rot-na | 337.23 | APE67-dihe-in | -74.09, -11.0 | -49.78, -56.09 | APE12-dist-na | 19.4192 | APE11-dist-na | 18.8177 | APE10-dist-na | 14.5978 | APE9-dist-out | 8.3718 | None | PTR342 | PTR342 | XRAY | 2.5 | 0.206 | 0.246 | A | 264.0 | 262.0 | 0 | 28 | 28 | 0 | [[191, 443]] | 1.0 | 6cz2 | TYR_PTK6_HUMAN | TYR | 3.3e-88 | 301.3 | 2.0 | 260.0 | 259.0 | 329 | 330 | 331 | 333 | 335 | 219 | 235 | 239 | 309 | 311 | 310 | 312.0 | 369 | 357 | 352 | 351 | 350 | 349 | 348 | 347 | 346 | 265 | Protein-tyrosine kinase 6 |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | PTK6 | PTK6_HUMAN | 6CZ2A | Q13882 | 182 | 443 | 451.0 | No_ligand | No_ligand | Inactive | DFGin | 5.3502 | 13.1432 | BLBplus | -121.1, 176.65 | 66.9, 22.32 | -67.74, 135.96 | 36.4, 96.02 | 85.0, -21.68 | out-out | out | 13.5103 | Saltbr-out | 12.6917 | HRD-in | -67.17, -59.02 | 88.03, -15.86 | out-out-out | SNCooo | out-out | ActLoopNT-out | 8.009 | ActLoopCT-out | TYR | APEdihe_oioai | APEdist_aaao | APE10-dihe-out | -114.8, 16.86 | APE9-dihe-in | -107.35, 157.15 | APE8-dihe-out | -58.54, -13.36 | APE8-rot-na | 337.23 | APE67-dihe-in | -74.09, -11.0 | -49.78, -56.09 | APE12-dist-na | 19.4192 | APE11-dist-na | 18.8177 | APE10-dist-na | 14.5978 | APE9-dist-out | 8.3718 | None | PTR342 | PTR342 | XRAY | 2.5 | 0.206 | 0.246 | A | 264.0 | 262.0 | 0 | 28 | 28 | 0 | [[191, 443]] | 1.0 | 6cz2 | Homo sapiens | TYR_PTK6_HUMAN | TYR | 3.3e-88 | 301.3 | 2.0 | 260.0 | 259.0 | 329 | 330 | 331 | 333 | 335 | 219 | 235 | 239 | 309 | 311 | 310 | 312.0 | 369 | 357 | 352 | 351 | 350 | 349 | 348 | 347 | 346 | 265 | Protein-tyrosine kinase 6 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|