KinCore

Spatial label	Dihedral label	Number of Chains	Percent	Representative
DFGin	BLAminus	1	100.0%	6AAMA

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Family	Gene	UniprotID	PDB	Resolution	Activity_label	Spatial_Dihedral_labels	ChelixSaltbr_label	ActLoopNT-ActLoopCT	APEtype	APEdihe_label	APEdist_label	Ligand	Ligand_type	Residues in structure	Unresolved residues in A-loop	Phosphorylation	Mutation	Protein
TYR	TYK2-2	TYK2_HUMAN	6AAMA	1.98	None	DFGin‑BLAminus	in-in	in-none	TYR	APEdihe_nnnai	APEdist_aaan	9T6	Type1	888 - 1178	0	None	C936A,Q969A,E971A,K972A,D1023N,I1114L,C1142A	Non-receptor tyrosine-protein kinase TYK2

Spatial label	Dihedral label	Number of Chains	Percent	Representative
DFGin	BLAminus	1	100.0%	6AAMA

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Family	Gene	UniprotID	PDB	Resolution	Activity_label	Spatial_Dihedral_labels	ChelixSaltbr_label	ActLoopNT-ActLoopCT	APEtype	APEdihe_label	APEdist_label	Ligand	Ligand_type	Residues in structure	Unresolved residues in A-loop	Phosphorylation	Mutation	Protein	Organism
TYR	TYK2-2	TYK2_HUMAN	6AAMA	1.98	None	DFGin‑BLAminus	in-in	in-none	TYR	APEdihe_nnnai	APEdist_aaan	9T6	Type1	888 - 1178	0	None	C936A,Q969A,E971A,K972A,D1023N,I1114L,C1142A	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens

Spatial label	Dihedral label	Number of Chains	Percent	Representative

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Family	Gene	UniprotID	PDB	Resolution	Activity_label	Spatial_Dihedral_labels	ChelixSaltbr_label	ActLoopNT-ActLoopCT	APEtype	APEdihe_label	APEdist_label	Ligand	Ligand_type	Residues in structure	Unresolved residues in A-loop	Phosphorylation	Mutation	Protein	Organism