PDB: 5YU9 — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 4 100.0% 5YU9D

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 5YU9A P00533 700 1017 1210.0 1E8:1101 Type1 Inactive DFGin 5.636 16.954 BLBtrans -125.21, 170.75 68.2, 24.35 -60.36, 133.88 165.48, 79.68 84.64, -7.33 out-out out 14.105 Saltbr-out 13.516 HRD-in -68.25, -48.62 80.2, -8.38 out-out-out SNCooo out-out ActLoopNT-out 6.623 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, -1.9 APE9-dihe-in -68.14, 141.09 APE8-dihe-in -83.65, 70.23 APE8-rot-na 33.58 APE67-dihe-in -73.94, -5.17 -61.14, -38.49 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 13.164 APE9-dist-out 8.325 T790M None None XRAY 1.95 0.203 0.222 A 331 302 16 0 0 12 [[712, 970]] 1.0 5yu9 TYR_EGFR_HUMAN TYR 8.4e-88 300.1 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5YU9B P00533 699 1011 1210.0 1E8:1101 Type1 Inactive DFGin 5.578 16.845 BLBtrans -112.64, 177.79 63.79, 24.69 -63.05, 134.78 163.6, 79.76 84.83, -6.07 out-out out 14.134 Saltbr-out 14.101 HRD-in -68.46, -48.55 81.72, -13.78 out-out-out SNCooo out-out ActLoopNT-out 6.519 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 119.76 APE8-dihe-in -84.19, 72.46 APE8-rot-na 28.56 APE67-dihe-in -69.8, -15.04 -60.51, -37.69 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.185 T790M None None XRAY 1.95 0.203 0.222 B 331 295 18 0 0 13 [[712, 970]] 1.0 5yu9 TYR_EGFR_HUMAN TYR 8.4e-88 300.1 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5YU9C P00533 697 1021 1210.0 1E8:1101 Type1 Inactive DFGin 5.67 16.652 BLBtrans -122.9, 169.66 70.91, 24.34 -64.7, 134.43 166.29, 81.69 95.85, -22.56 out-out out 13.826 Saltbr-out 13.722 HRD-in -69.25, -50.19 81.18, -12.38 out-out-out SNCooo out-out ActLoopNT-out 6.805 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, 107.02 APE9-dihe-in -132.02, 145.19 APE8-dihe-in -82.44, 66.61 APE8-rot-na 16.92 APE67-dihe-in -75.02, -8.16 -59.33, -36.13 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.992 APE9-dist-out 8.462 T790M None None XRAY 1.95 0.203 0.222 C 331 306 16 0 0 12 [[712, 970]] 1.0 5yu9 TYR_EGFR_HUMAN TYR 8.4e-88 300.1 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5YU9D P00533 700 1012 1210.0 1E8:1101 Type1 Inactive DFGin 5.71 16.766 BLBtrans -121.88, 171.32 72.04, 19.53 -55.62, 135.13 163.77, 67.42 83.7, -13.08 out-out out 13.758 Saltbr-out 13.361 HRD-in -69.57, -49.84 80.09, -14.78 out-out-out SNCooo out-out ActLoopNT-out 6.597 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 151.91 APE8-dihe-in -82.51, 73.37 APE8-rot-na 30.07 APE67-dihe-in -70.37, -12.42 -60.68, -39.06 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.027 T790M None None XRAY 1.95 0.203 0.222 D 331 300 13 0 0 13 [[712, 970]] 1.0 5yu9 TYR_EGFR_HUMAN TYR 8.4e-88 300.1 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 5YU9 — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 4 100.0% 5YU9D

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 5YU9A P00533 700 1017 1210.0 1E8:1101 Type1 Inactive DFGin 5.636 16.954 BLBtrans -125.21, 170.75 68.2, 24.35 -60.36, 133.88 165.48, 79.68 84.64, -7.33 out-out out 14.105 Saltbr-out 13.516 HRD-in -68.25, -48.62 80.2, -8.38 out-out-out SNCooo out-out ActLoopNT-out 6.623 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, -1.9 APE9-dihe-in -68.14, 141.09 APE8-dihe-in -83.65, 70.23 APE8-rot-na 33.58 APE67-dihe-in -73.94, -5.17 -61.14, -38.49 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 13.164 APE9-dist-out 8.325 T790M None None XRAY 1.95 0.203 0.222 A 331 302 16 0 0 12 [[712, 970]] 1.0 5yu9 Homo sapiens TYR_EGFR_HUMAN TYR 8.4e-88 300.1 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5YU9B P00533 699 1011 1210.0 1E8:1101 Type1 Inactive DFGin 5.578 16.845 BLBtrans -112.64, 177.79 63.79, 24.69 -63.05, 134.78 163.6, 79.76 84.83, -6.07 out-out out 14.134 Saltbr-out 14.101 HRD-in -68.46, -48.55 81.72, -13.78 out-out-out SNCooo out-out ActLoopNT-out 6.519 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 119.76 APE8-dihe-in -84.19, 72.46 APE8-rot-na 28.56 APE67-dihe-in -69.8, -15.04 -60.51, -37.69 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.185 T790M None None XRAY 1.95 0.203 0.222 B 331 295 18 0 0 13 [[712, 970]] 1.0 5yu9 Homo sapiens TYR_EGFR_HUMAN TYR 8.4e-88 300.1 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5YU9C P00533 697 1021 1210.0 1E8:1101 Type1 Inactive DFGin 5.67 16.652 BLBtrans -122.9, 169.66 70.91, 24.34 -64.7, 134.43 166.29, 81.69 95.85, -22.56 out-out out 13.826 Saltbr-out 13.722 HRD-in -69.25, -50.19 81.18, -12.38 out-out-out SNCooo out-out ActLoopNT-out 6.805 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, 107.02 APE9-dihe-in -132.02, 145.19 APE8-dihe-in -82.44, 66.61 APE8-rot-na 16.92 APE67-dihe-in -75.02, -8.16 -59.33, -36.13 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.992 APE9-dist-out 8.462 T790M None None XRAY 1.95 0.203 0.222 C 331 306 16 0 0 12 [[712, 970]] 1.0 5yu9 Homo sapiens TYR_EGFR_HUMAN TYR 8.4e-88 300.1 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5YU9D P00533 700 1012 1210.0 1E8:1101 Type1 Inactive DFGin 5.71 16.766 BLBtrans -121.88, 171.32 72.04, 19.53 -55.62, 135.13 163.77, 67.42 83.7, -13.08 out-out out 13.758 Saltbr-out 13.361 HRD-in -69.57, -49.84 80.09, -14.78 out-out-out SNCooo out-out ActLoopNT-out 6.597 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 151.91 APE8-dihe-in -82.51, 73.37 APE8-rot-na 30.07 APE67-dihe-in -70.37, -12.42 -60.68, -39.06 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.027 T790M None None XRAY 1.95 0.203 0.222 D 331 300 13 0 0 13 [[712, 970]] 1.0 5yu9 Homo sapiens TYR_EGFR_HUMAN TYR 8.4e-88 300.1 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 5YU9 — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name