PDB: 5WO4 — TYR JAK1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 5WO4A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 5WO4A P23458 854 1154 1154.0 B7V:2001 Type1 Inactive DFGin 6.5589 13.4747 ABAminus -113.4, 5.79 -147.65, 137.71 -131.93, 25.73 295.23, 90.95 -54.73, -30.34 in-in in 7.6759 Saltbr-in 2.7544 HRD-in -72.7, -46.52 67.85, -2.92 in-in-out SNCiio in-out ActLoopNT-in 2.8208 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -113.62, 42.17 APE9-dihe-in -67.76, 140.08 APE8-dihe-in -81.09, 72.14 APE8-rot-na 29.77 APE67-dihe-in -75.22, -1.83 -52.55, -34.79 APE12-dist-na 10.7973 APE11-dist-na 12.9011 APE10-dist-na 10.4662 APE9-dist-in 6.8227 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.84 0.188 0.211 A 302.0 294.0 7 31 31 0 [[583, 847], [875, 1151]] 2.0 5wo4 TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 5WO4B P23458 865 1154 1154.0 B7V:2001 Type1 Inactive DFGin 6.5504 13.4107 ABAminus -111.8, 3.6 -145.5, 139.23 -132.92, 27.81 292.27, 90.98 -57.76, -28.76 in-in in 7.6152 Saltbr-in 2.7806 HRD-in -72.82, -49.06 69.56, 1.39 in-in-out SNCiio in-out ActLoopNT-in 2.8385 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -114.71, 39.74 APE9-dihe-in -66.32, 138.27 APE8-dihe-in -78.58, 73.11 APE8-rot-na 28.91 APE67-dihe-in -75.88, -0.88 -52.5, -34.22 APE12-dist-na 10.8657 APE11-dist-na 12.9297 APE10-dist-na 10.505 APE9-dist-in 6.7428 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.84 0.188 0.211 B 302.0 282.0 8 31 31 0 [[583, 847], [875, 1151]] 2.0 5wo4 TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

PDB: 5WO4 — TYR JAK1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 5WO4A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 5WO4A P23458 854 1154 1154.0 B7V:2001 Type1 Inactive DFGin 6.5589 13.4747 ABAminus -113.4, 5.79 -147.65, 137.71 -131.93, 25.73 295.23, 90.95 -54.73, -30.34 in-in in 7.6759 Saltbr-in 2.7544 HRD-in -72.7, -46.52 67.85, -2.92 in-in-out SNCiio in-out ActLoopNT-in 2.8208 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -113.62, 42.17 APE9-dihe-in -67.76, 140.08 APE8-dihe-in -81.09, 72.14 APE8-rot-na 29.77 APE67-dihe-in -75.22, -1.83 -52.55, -34.79 APE12-dist-na 10.7973 APE11-dist-na 12.9011 APE10-dist-na 10.4662 APE9-dist-in 6.8227 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.84 0.188 0.211 A 302.0 294.0 7 31 31 0 [[583, 847], [875, 1151]] 2.0 5wo4 Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 5WO4B P23458 865 1154 1154.0 B7V:2001 Type1 Inactive DFGin 6.5504 13.4107 ABAminus -111.8, 3.6 -145.5, 139.23 -132.92, 27.81 292.27, 90.98 -57.76, -28.76 in-in in 7.6152 Saltbr-in 2.7806 HRD-in -72.82, -49.06 69.56, 1.39 in-in-out SNCiio in-out ActLoopNT-in 2.8385 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -114.71, 39.74 APE9-dihe-in -66.32, 138.27 APE8-dihe-in -78.58, 73.11 APE8-rot-na 28.91 APE67-dihe-in -75.88, -0.88 -52.5, -34.22 APE12-dist-na 10.8657 APE11-dist-na 12.9297 APE10-dist-na 10.505 APE9-dist-in 6.7428 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.84 0.188 0.211 B 302.0 282.0 8 31 31 0 [[583, 847], [875, 1151]] 2.0 5wo4 Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

PDB: 5WO4 — TYR JAK1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name