| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMK | CAMK2A | KCC2A_RAT | 5U6YA | P11275 | 13 | 472 | 478.0 | No_ligand | No_ligand | Active | DFGin | 6.8652 | 14.0312 | BLAminus | -131.86, 139.31 | 77.49, 110.85 | -122.06, 32.93 | 286.68, 71.99 | -61.48, -26.61 | in-in | in | 9.3109 | Saltbr-in | 2.9308 | HRD-in | -73.13, -44.6 | 73.87, -20.22 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8751 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -148.25, 149.7 | APE9-dihe-na | 143.17, -171.02 | APE8-dihe-in | -118.35, 128.47 | APE8-rot-in | 303.96 | APE67-dihe-in | -66.76, -18.7 | -40.04, -52.83 | APE12-dist-in | 10.2521 | APE11-dist-in | 11.7562 | APE10-dist-in | 5.9961 | APE9-dist-in | 3.9642 | None | None | None | EM | 20.0 | 999.0 | 999.0 | A | 461.0 | 458.0 | 0 | 28 | 28 | 0 | [[13, 271]] | 1.0 | 5u6y | Rattus norvegicus | CAMK_CAMK2A_RAT | CAMK | 5.4e-96 | 327.3 | 1.0 | 256.0 | 256.0 | 155 | 156 | 157 | 159 | 161 | 42 | 60 | 64 | 132 | 134 | 133 | 135.0 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 90 | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| CAMK | CAMK2A | KCC2A_RAT | 5U6YB | P11275 | 13 | 472 | 478.0 | No_ligand | No_ligand | Active | DFGin | 6.8652 | 14.0319 | BLAminus | -131.95, 139.31 | 77.48, 110.85 | -122.06, 32.98 | 286.65, 71.96 | -61.49, -26.64 | in-in | in | 9.3109 | Saltbr-in | 2.93 | HRD-in | -73.09, -44.73 | 74.01, -20.3 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8752 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -148.28, 149.66 | APE9-dihe-na | 143.24, -170.9 | APE8-dihe-in | -118.43, 128.46 | APE8-rot-in | 303.94 | APE67-dihe-in | -66.75, -18.73 | -40.11, -52.72 | APE12-dist-in | 10.2524 | APE11-dist-in | 11.7568 | APE10-dist-in | 5.996 | APE9-dist-in | 3.9639 | None | None | None | EM | 20.0 | 999.0 | 999.0 | B | 461.0 | 458.0 | 0 | 28 | 28 | 0 | [[13, 271]] | 1.0 | 5u6y | Rattus norvegicus | CAMK_CAMK2A_RAT | CAMK | 5.4e-96 | 327.3 | 1.0 | 256.0 | 256.0 | 155 | 156 | 157 | 159 | 161 | 42 | 60 | 64 | 132 | 134 | 133 | 135.0 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 90 | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| CAMK | CAMK2A | KCC2A_RAT | 5U6YC | P11275 | 13 | 472 | 478.0 | No_ligand | No_ligand | Active | DFGin | 6.8649 | 14.0315 | BLAminus | -131.96, 139.34 | 77.44, 110.96 | -122.08, 32.86 | 286.64, 72.06 | -61.52, -26.54 | in-in | in | 9.3104 | Saltbr-in | 2.9307 | HRD-in | -73.14, -44.67 | 73.9, -20.21 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8748 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -148.22, 149.66 | APE9-dihe-na | 143.26, -171.08 | APE8-dihe-in | -118.34, 128.48 | APE8-rot-in | 303.98 | APE67-dihe-in | -66.83, -18.67 | -40.06, -52.78 | APE12-dist-in | 10.2506 | APE11-dist-in | 11.7548 | APE10-dist-in | 5.9948 | APE9-dist-in | 3.964 | None | None | None | EM | 20.0 | 999.0 | 999.0 | C | 461.0 | 458.0 | 0 | 28 | 28 | 0 | [[13, 271]] | 1.0 | 5u6y | Rattus norvegicus | CAMK_CAMK2A_RAT | CAMK | 5.4e-96 | 327.3 | 1.0 | 256.0 | 256.0 | 155 | 156 | 157 | 159 | 161 | 42 | 60 | 64 | 132 | 134 | 133 | 135.0 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 90 | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| CAMK | CAMK2A | KCC2A_RAT | 5U6YD | P11275 | 13 | 472 | 478.0 | No_ligand | No_ligand | Active | DFGin | 6.8658 | 14.0321 | BLAminus | -131.91, 139.34 | 77.49, 110.87 | -122.11, 32.91 | 286.66, 71.93 | -61.43, -26.54 | in-in | in | 9.3109 | Saltbr-in | 2.9307 | HRD-in | -73.12, -44.58 | 73.75, -20.14 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8759 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -148.2, 149.78 | APE9-dihe-na | 143.1, -171.01 | APE8-dihe-in | -118.32, 128.47 | APE8-rot-in | 303.98 | APE67-dihe-in | -66.82, -18.71 | -40.07, -52.72 | APE12-dist-in | 10.2515 | APE11-dist-in | 11.7558 | APE10-dist-in | 5.9953 | APE9-dist-in | 3.964 | None | None | None | EM | 20.0 | 999.0 | 999.0 | D | 461.0 | 458.0 | 0 | 28 | 28 | 0 | [[13, 271]] | 1.0 | 5u6y | Rattus norvegicus | CAMK_CAMK2A_RAT | CAMK | 5.4e-96 | 327.3 | 1.0 | 256.0 | 256.0 | 155 | 156 | 157 | 159 | 161 | 42 | 60 | 64 | 132 | 134 | 133 | 135.0 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 90 | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| CAMK | CAMK2A | KCC2A_RAT | 5U6YE | P11275 | 13 | 472 | 478.0 | No_ligand | No_ligand | Active | DFGin | 6.8653 | 14.031 | BLAminus | -131.93, 139.32 | 77.45, 110.92 | -122.11, 33.05 | 286.68, 71.92 | -61.6, -26.5 | in-in | in | 9.3111 | Saltbr-in | 2.9311 | HRD-in | -73.04, -44.67 | 73.88, -20.22 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8751 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -148.16, 149.72 | APE9-dihe-na | 143.17, -171.04 | APE8-dihe-in | -118.33, 128.47 | APE8-rot-in | 303.95 | APE67-dihe-in | -66.81, -18.72 | -40.11, -52.72 | APE12-dist-in | 10.252 | APE11-dist-in | 11.7565 | APE10-dist-in | 5.9971 | APE9-dist-in | 3.9628 | None | None | None | EM | 20.0 | 999.0 | 999.0 | E | 461.0 | 458.0 | 0 | 28 | 28 | 0 | [[13, 271]] | 1.0 | 5u6y | Rattus norvegicus | CAMK_CAMK2A_RAT | CAMK | 5.4e-96 | 327.3 | 1.0 | 256.0 | 256.0 | 155 | 156 | 157 | 159 | 161 | 42 | 60 | 64 | 132 | 134 | 133 | 135.0 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 90 | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| CAMK | CAMK2A | KCC2A_RAT | 5U6YF | P11275 | 13 | 472 | 478.0 | No_ligand | No_ligand | Active | DFGin | 6.8648 | 14.0316 | BLAminus | -131.93, 139.32 | 77.42, 110.87 | -122.1, 32.98 | 286.71, 71.94 | -61.53, -26.5 | in-in | in | 9.3111 | Saltbr-in | 2.9317 | HRD-in | -73.09, -44.66 | 73.92, -20.32 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8752 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -148.26, 149.65 | APE9-dihe-na | 143.17, -171.02 | APE8-dihe-in | -118.33, 128.42 | APE8-rot-in | 304.0 | APE67-dihe-in | -66.75, -18.74 | -40.02, -52.76 | APE12-dist-in | 10.2512 | APE11-dist-in | 11.756 | APE10-dist-in | 5.9961 | APE9-dist-in | 3.9622 | None | None | None | EM | 20.0 | 999.0 | 999.0 | F | 461.0 | 458.0 | 0 | 28 | 28 | 0 | [[13, 271]] | 1.0 | 5u6y | Rattus norvegicus | CAMK_CAMK2A_RAT | CAMK | 5.4e-96 | 327.3 | 1.0 | 256.0 | 256.0 | 155 | 156 | 157 | 159 | 161 | 42 | 60 | 64 | 132 | 134 | 133 | 135.0 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 90 | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| CAMK | CAMK2A | KCC2A_RAT | 5U6YG | P11275 | 13 | 472 | 478.0 | No_ligand | No_ligand | Active | DFGin | 6.8662 | 14.0319 | BLAminus | -131.85, 139.33 | 77.48, 110.87 | -122.11, 32.96 | 286.62, 72.03 | -61.49, -26.59 | in-in | in | 9.3106 | Saltbr-in | 2.9307 | HRD-in | -73.18, -44.61 | 73.91, -20.27 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.875 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -148.24, 149.76 | APE9-dihe-na | 143.06, -171.13 | APE8-dihe-in | -118.25, 128.47 | APE8-rot-in | 304.07 | APE67-dihe-in | -66.77, -18.8 | -40.08, -52.75 | APE12-dist-in | 10.2523 | APE11-dist-in | 11.7562 | APE10-dist-in | 5.996 | APE9-dist-in | 3.9635 | None | None | None | EM | 20.0 | 999.0 | 999.0 | G | 461.0 | 458.0 | 0 | 28 | 28 | 0 | [[13, 271]] | 1.0 | 5u6y | Rattus norvegicus | CAMK_CAMK2A_RAT | CAMK | 5.4e-96 | 327.3 | 1.0 | 256.0 | 256.0 | 155 | 156 | 157 | 159 | 161 | 42 | 60 | 64 | 132 | 134 | 133 | 135.0 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 90 | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| CAMK | CAMK2A | KCC2A_RAT | 5U6YH | P11275 | 13 | 472 | 478.0 | No_ligand | No_ligand | Active | DFGin | 6.8658 | 14.0323 | BLAminus | -131.88, 139.32 | 77.5, 110.88 | -122.07, 32.96 | 286.74, 71.95 | -61.56, -26.5 | in-in | in | 9.3107 | Saltbr-in | 2.9315 | HRD-in | -73.06, -44.63 | 73.85, -20.24 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8757 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -148.2, 149.67 | APE9-dihe-na | 143.16, -171.09 | APE8-dihe-in | -118.29, 128.44 | APE8-rot-in | 303.93 | APE67-dihe-in | -66.72, -18.73 | -40.03, -52.81 | APE12-dist-in | 10.2529 | APE11-dist-in | 11.7563 | APE10-dist-in | 5.9959 | APE9-dist-in | 3.9632 | None | None | None | EM | 20.0 | 999.0 | 999.0 | H | 461.0 | 458.0 | 0 | 28 | 28 | 0 | [[13, 271]] | 1.0 | 5u6y | Rattus norvegicus | CAMK_CAMK2A_RAT | CAMK | 5.4e-96 | 327.3 | 1.0 | 256.0 | 256.0 | 155 | 156 | 157 | 159 | 161 | 42 | 60 | 64 | 132 | 134 | 133 | 135.0 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 90 | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| CAMK | CAMK2A | KCC2A_RAT | 5U6YI | P11275 | 13 | 472 | 478.0 | No_ligand | No_ligand | Active | DFGin | 6.865 | 14.0314 | BLAminus | -131.88, 139.32 | 77.51, 110.82 | -122.03, 32.96 | 286.72, 72.01 | -61.6, -26.54 | in-in | in | 9.3111 | Saltbr-in | 2.9299 | HRD-in | -73.14, -44.59 | 73.89, -20.24 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8747 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -148.18, 149.76 | APE9-dihe-na | 143.1, -170.97 | APE8-dihe-in | -118.34, 128.48 | APE8-rot-in | 304.0 | APE67-dihe-in | -66.74, -18.77 | -40.07, -52.78 | APE12-dist-in | 10.2522 | APE11-dist-in | 11.7557 | APE10-dist-in | 5.9959 | APE9-dist-in | 3.963 | None | None | None | EM | 20.0 | 999.0 | 999.0 | I | 461.0 | 458.0 | 0 | 28 | 28 | 0 | [[13, 271]] | 1.0 | 5u6y | Rattus norvegicus | CAMK_CAMK2A_RAT | CAMK | 5.4e-96 | 327.3 | 1.0 | 256.0 | 256.0 | 155 | 156 | 157 | 159 | 161 | 42 | 60 | 64 | 132 | 134 | 133 | 135.0 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 90 | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| CAMK | CAMK2A | KCC2A_RAT | 5U6YJ | P11275 | 13 | 472 | 478.0 | No_ligand | No_ligand | Active | DFGin | 6.8645 | 14.0315 | BLAminus | -131.96, 139.32 | 77.43, 110.94 | -122.11, 32.97 | 286.66, 72.03 | -61.61, -26.48 | in-in | in | 9.3113 | Saltbr-in | 2.9315 | HRD-in | -73.06, -44.6 | 73.89, -20.28 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8753 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -148.26, 149.71 | APE9-dihe-na | 143.13, -170.97 | APE8-dihe-in | -118.31, 128.48 | APE8-rot-in | 304.0 | APE67-dihe-in | -66.76, -18.72 | -40.1, -52.77 | APE12-dist-in | 10.252 | APE11-dist-in | 11.7565 | APE10-dist-in | 5.9964 | APE9-dist-in | 3.9629 | None | None | None | EM | 20.0 | 999.0 | 999.0 | J | 461.0 | 458.0 | 0 | 28 | 28 | 0 | [[13, 271]] | 1.0 | 5u6y | Rattus norvegicus | CAMK_CAMK2A_RAT | CAMK | 5.4e-96 | 327.3 | 1.0 | 256.0 | 256.0 | 155 | 156 | 157 | 159 | 161 | 42 | 60 | 64 | 132 | 134 | 133 | 135.0 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 90 | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| CAMK | CAMK2A | KCC2A_RAT | 5U6YK | P11275 | 13 | 472 | 478.0 | No_ligand | No_ligand | Active | DFGin | 6.8659 | 14.0325 | BLAminus | -131.9, 139.29 | 77.45, 110.86 | -122.02, 32.92 | 286.62, 72.03 | -61.54, -26.54 | in-in | in | 9.311 | Saltbr-in | 2.9304 | HRD-in | -73.15, -44.63 | 73.76, -20.13 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8748 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -148.25, 149.7 | APE9-dihe-na | 143.13, -171.07 | APE8-dihe-in | -118.27, 128.49 | APE8-rot-in | 303.97 | APE67-dihe-in | -66.81, -18.77 | -40.05, -52.72 | APE12-dist-in | 10.2519 | APE11-dist-in | 11.7557 | APE10-dist-in | 5.9964 | APE9-dist-in | 3.9627 | None | None | None | EM | 20.0 | 999.0 | 999.0 | K | 461.0 | 458.0 | 0 | 28 | 28 | 0 | [[13, 271]] | 1.0 | 5u6y | Rattus norvegicus | CAMK_CAMK2A_RAT | CAMK | 5.4e-96 | 327.3 | 1.0 | 256.0 | 256.0 | 155 | 156 | 157 | 159 | 161 | 42 | 60 | 64 | 132 | 134 | 133 | 135.0 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 90 | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| CAMK | CAMK2A | KCC2A_RAT | 5U6YL | P11275 | 13 | 472 | 478.0 | No_ligand | No_ligand | Active | DFGin | 6.8649 | 14.0311 | BLAminus | -131.92, 139.31 | 77.56, 110.83 | -122.08, 32.9 | 286.66, 71.99 | -61.46, -26.52 | in-in | in | 9.3108 | Saltbr-in | 2.931 | HRD-in | -73.09, -44.69 | 73.91, -20.23 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8753 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -148.24, 149.66 | APE9-dihe-na | 143.13, -170.99 | APE8-dihe-in | -118.31, 128.48 | APE8-rot-in | 303.97 | APE67-dihe-in | -66.81, -18.73 | -40.08, -52.69 | APE12-dist-in | 10.2518 | APE11-dist-in | 11.7549 | APE10-dist-in | 5.9952 | APE9-dist-in | 3.9638 | None | None | None | EM | 20.0 | 999.0 | 999.0 | L | 461.0 | 458.0 | 0 | 28 | 28 | 0 | [[13, 271]] | 1.0 | 5u6y | Rattus norvegicus | CAMK_CAMK2A_RAT | CAMK | 5.4e-96 | 327.3 | 1.0 | 256.0 | 256.0 | 155 | 156 | 157 | 159 | 161 | 42 | 60 | 64 | 132 | 134 | 133 | 135.0 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 90 | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMK | CAMK2A | KCC2A_RAT | 5U6YA | P11275 | 13 | 472 | 478.0 | No_ligand | No_ligand | Active | DFGin | 6.8652 | 14.0312 | BLAminus | -131.86, 139.31 | 77.49, 110.85 | -122.06, 32.93 | 286.68, 71.99 | -61.48, -26.61 | in-in | in | 9.3109 | Saltbr-in | 2.9308 | HRD-in | -73.13, -44.6 | 73.87, -20.22 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8751 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -148.25, 149.7 | APE9-dihe-na | 143.17, -171.02 | APE8-dihe-in | -118.35, 128.47 | APE8-rot-in | 303.96 | APE67-dihe-in | -66.76, -18.7 | -40.04, -52.83 | APE12-dist-in | 10.2521 | APE11-dist-in | 11.7562 | APE10-dist-in | 5.9961 | APE9-dist-in | 3.9642 | None | None | None | EM | 20.0 | 999.0 | 999.0 | A | 461.0 | 458.0 | 0 | 28 | 28 | 0 | [[13, 271]] | 1.0 | 5u6y | Rattus norvegicus | CAMK_CAMK2A_RAT | CAMK | 5.4e-96 | 327.3 | 1.0 | 256.0 | 256.0 | 155 | 156 | 157 | 159 | 161 | 42 | 60 | 64 | 132 | 134 | 133 | 135.0 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 90 | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| CAMK | CAMK2A | KCC2A_RAT | 5U6YB | P11275 | 13 | 472 | 478.0 | No_ligand | No_ligand | Active | DFGin | 6.8652 | 14.0319 | BLAminus | -131.95, 139.31 | 77.48, 110.85 | -122.06, 32.98 | 286.65, 71.96 | -61.49, -26.64 | in-in | in | 9.3109 | Saltbr-in | 2.93 | HRD-in | -73.09, -44.73 | 74.01, -20.3 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8752 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -148.28, 149.66 | APE9-dihe-na | 143.24, -170.9 | APE8-dihe-in | -118.43, 128.46 | APE8-rot-in | 303.94 | APE67-dihe-in | -66.75, -18.73 | -40.11, -52.72 | APE12-dist-in | 10.2524 | APE11-dist-in | 11.7568 | APE10-dist-in | 5.996 | APE9-dist-in | 3.9639 | None | None | None | EM | 20.0 | 999.0 | 999.0 | B | 461.0 | 458.0 | 0 | 28 | 28 | 0 | [[13, 271]] | 1.0 | 5u6y | Rattus norvegicus | CAMK_CAMK2A_RAT | CAMK | 5.4e-96 | 327.3 | 1.0 | 256.0 | 256.0 | 155 | 156 | 157 | 159 | 161 | 42 | 60 | 64 | 132 | 134 | 133 | 135.0 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 90 | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| CAMK | CAMK2A | KCC2A_RAT | 5U6YC | P11275 | 13 | 472 | 478.0 | No_ligand | No_ligand | Active | DFGin | 6.8649 | 14.0315 | BLAminus | -131.96, 139.34 | 77.44, 110.96 | -122.08, 32.86 | 286.64, 72.06 | -61.52, -26.54 | in-in | in | 9.3104 | Saltbr-in | 2.9307 | HRD-in | -73.14, -44.67 | 73.9, -20.21 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8748 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -148.22, 149.66 | APE9-dihe-na | 143.26, -171.08 | APE8-dihe-in | -118.34, 128.48 | APE8-rot-in | 303.98 | APE67-dihe-in | -66.83, -18.67 | -40.06, -52.78 | APE12-dist-in | 10.2506 | APE11-dist-in | 11.7548 | APE10-dist-in | 5.9948 | APE9-dist-in | 3.964 | None | None | None | EM | 20.0 | 999.0 | 999.0 | C | 461.0 | 458.0 | 0 | 28 | 28 | 0 | [[13, 271]] | 1.0 | 5u6y | Rattus norvegicus | CAMK_CAMK2A_RAT | CAMK | 5.4e-96 | 327.3 | 1.0 | 256.0 | 256.0 | 155 | 156 | 157 | 159 | 161 | 42 | 60 | 64 | 132 | 134 | 133 | 135.0 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 90 | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| CAMK | CAMK2A | KCC2A_RAT | 5U6YD | P11275 | 13 | 472 | 478.0 | No_ligand | No_ligand | Active | DFGin | 6.8658 | 14.0321 | BLAminus | -131.91, 139.34 | 77.49, 110.87 | -122.11, 32.91 | 286.66, 71.93 | -61.43, -26.54 | in-in | in | 9.3109 | Saltbr-in | 2.9307 | HRD-in | -73.12, -44.58 | 73.75, -20.14 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8759 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -148.2, 149.78 | APE9-dihe-na | 143.1, -171.01 | APE8-dihe-in | -118.32, 128.47 | APE8-rot-in | 303.98 | APE67-dihe-in | -66.82, -18.71 | -40.07, -52.72 | APE12-dist-in | 10.2515 | APE11-dist-in | 11.7558 | APE10-dist-in | 5.9953 | APE9-dist-in | 3.964 | None | None | None | EM | 20.0 | 999.0 | 999.0 | D | 461.0 | 458.0 | 0 | 28 | 28 | 0 | [[13, 271]] | 1.0 | 5u6y | Rattus norvegicus | CAMK_CAMK2A_RAT | CAMK | 5.4e-96 | 327.3 | 1.0 | 256.0 | 256.0 | 155 | 156 | 157 | 159 | 161 | 42 | 60 | 64 | 132 | 134 | 133 | 135.0 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 90 | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| CAMK | CAMK2A | KCC2A_RAT | 5U6YE | P11275 | 13 | 472 | 478.0 | No_ligand | No_ligand | Active | DFGin | 6.8653 | 14.031 | BLAminus | -131.93, 139.32 | 77.45, 110.92 | -122.11, 33.05 | 286.68, 71.92 | -61.6, -26.5 | in-in | in | 9.3111 | Saltbr-in | 2.9311 | HRD-in | -73.04, -44.67 | 73.88, -20.22 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8751 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -148.16, 149.72 | APE9-dihe-na | 143.17, -171.04 | APE8-dihe-in | -118.33, 128.47 | APE8-rot-in | 303.95 | APE67-dihe-in | -66.81, -18.72 | -40.11, -52.72 | APE12-dist-in | 10.252 | APE11-dist-in | 11.7565 | APE10-dist-in | 5.9971 | APE9-dist-in | 3.9628 | None | None | None | EM | 20.0 | 999.0 | 999.0 | E | 461.0 | 458.0 | 0 | 28 | 28 | 0 | [[13, 271]] | 1.0 | 5u6y | Rattus norvegicus | CAMK_CAMK2A_RAT | CAMK | 5.4e-96 | 327.3 | 1.0 | 256.0 | 256.0 | 155 | 156 | 157 | 159 | 161 | 42 | 60 | 64 | 132 | 134 | 133 | 135.0 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 90 | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| CAMK | CAMK2A | KCC2A_RAT | 5U6YF | P11275 | 13 | 472 | 478.0 | No_ligand | No_ligand | Active | DFGin | 6.8648 | 14.0316 | BLAminus | -131.93, 139.32 | 77.42, 110.87 | -122.1, 32.98 | 286.71, 71.94 | -61.53, -26.5 | in-in | in | 9.3111 | Saltbr-in | 2.9317 | HRD-in | -73.09, -44.66 | 73.92, -20.32 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8752 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -148.26, 149.65 | APE9-dihe-na | 143.17, -171.02 | APE8-dihe-in | -118.33, 128.42 | APE8-rot-in | 304.0 | APE67-dihe-in | -66.75, -18.74 | -40.02, -52.76 | APE12-dist-in | 10.2512 | APE11-dist-in | 11.756 | APE10-dist-in | 5.9961 | APE9-dist-in | 3.9622 | None | None | None | EM | 20.0 | 999.0 | 999.0 | F | 461.0 | 458.0 | 0 | 28 | 28 | 0 | [[13, 271]] | 1.0 | 5u6y | Rattus norvegicus | CAMK_CAMK2A_RAT | CAMK | 5.4e-96 | 327.3 | 1.0 | 256.0 | 256.0 | 155 | 156 | 157 | 159 | 161 | 42 | 60 | 64 | 132 | 134 | 133 | 135.0 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 90 | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| CAMK | CAMK2A | KCC2A_RAT | 5U6YG | P11275 | 13 | 472 | 478.0 | No_ligand | No_ligand | Active | DFGin | 6.8662 | 14.0319 | BLAminus | -131.85, 139.33 | 77.48, 110.87 | -122.11, 32.96 | 286.62, 72.03 | -61.49, -26.59 | in-in | in | 9.3106 | Saltbr-in | 2.9307 | HRD-in | -73.18, -44.61 | 73.91, -20.27 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.875 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -148.24, 149.76 | APE9-dihe-na | 143.06, -171.13 | APE8-dihe-in | -118.25, 128.47 | APE8-rot-in | 304.07 | APE67-dihe-in | -66.77, -18.8 | -40.08, -52.75 | APE12-dist-in | 10.2523 | APE11-dist-in | 11.7562 | APE10-dist-in | 5.996 | APE9-dist-in | 3.9635 | None | None | None | EM | 20.0 | 999.0 | 999.0 | G | 461.0 | 458.0 | 0 | 28 | 28 | 0 | [[13, 271]] | 1.0 | 5u6y | Rattus norvegicus | CAMK_CAMK2A_RAT | CAMK | 5.4e-96 | 327.3 | 1.0 | 256.0 | 256.0 | 155 | 156 | 157 | 159 | 161 | 42 | 60 | 64 | 132 | 134 | 133 | 135.0 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 90 | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| CAMK | CAMK2A | KCC2A_RAT | 5U6YH | P11275 | 13 | 472 | 478.0 | No_ligand | No_ligand | Active | DFGin | 6.8658 | 14.0323 | BLAminus | -131.88, 139.32 | 77.5, 110.88 | -122.07, 32.96 | 286.74, 71.95 | -61.56, -26.5 | in-in | in | 9.3107 | Saltbr-in | 2.9315 | HRD-in | -73.06, -44.63 | 73.85, -20.24 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8757 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -148.2, 149.67 | APE9-dihe-na | 143.16, -171.09 | APE8-dihe-in | -118.29, 128.44 | APE8-rot-in | 303.93 | APE67-dihe-in | -66.72, -18.73 | -40.03, -52.81 | APE12-dist-in | 10.2529 | APE11-dist-in | 11.7563 | APE10-dist-in | 5.9959 | APE9-dist-in | 3.9632 | None | None | None | EM | 20.0 | 999.0 | 999.0 | H | 461.0 | 458.0 | 0 | 28 | 28 | 0 | [[13, 271]] | 1.0 | 5u6y | Rattus norvegicus | CAMK_CAMK2A_RAT | CAMK | 5.4e-96 | 327.3 | 1.0 | 256.0 | 256.0 | 155 | 156 | 157 | 159 | 161 | 42 | 60 | 64 | 132 | 134 | 133 | 135.0 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 90 | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| CAMK | CAMK2A | KCC2A_RAT | 5U6YI | P11275 | 13 | 472 | 478.0 | No_ligand | No_ligand | Active | DFGin | 6.865 | 14.0314 | BLAminus | -131.88, 139.32 | 77.51, 110.82 | -122.03, 32.96 | 286.72, 72.01 | -61.6, -26.54 | in-in | in | 9.3111 | Saltbr-in | 2.9299 | HRD-in | -73.14, -44.59 | 73.89, -20.24 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8747 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -148.18, 149.76 | APE9-dihe-na | 143.1, -170.97 | APE8-dihe-in | -118.34, 128.48 | APE8-rot-in | 304.0 | APE67-dihe-in | -66.74, -18.77 | -40.07, -52.78 | APE12-dist-in | 10.2522 | APE11-dist-in | 11.7557 | APE10-dist-in | 5.9959 | APE9-dist-in | 3.963 | None | None | None | EM | 20.0 | 999.0 | 999.0 | I | 461.0 | 458.0 | 0 | 28 | 28 | 0 | [[13, 271]] | 1.0 | 5u6y | Rattus norvegicus | CAMK_CAMK2A_RAT | CAMK | 5.4e-96 | 327.3 | 1.0 | 256.0 | 256.0 | 155 | 156 | 157 | 159 | 161 | 42 | 60 | 64 | 132 | 134 | 133 | 135.0 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 90 | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| CAMK | CAMK2A | KCC2A_RAT | 5U6YJ | P11275 | 13 | 472 | 478.0 | No_ligand | No_ligand | Active | DFGin | 6.8645 | 14.0315 | BLAminus | -131.96, 139.32 | 77.43, 110.94 | -122.11, 32.97 | 286.66, 72.03 | -61.61, -26.48 | in-in | in | 9.3113 | Saltbr-in | 2.9315 | HRD-in | -73.06, -44.6 | 73.89, -20.28 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8753 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -148.26, 149.71 | APE9-dihe-na | 143.13, -170.97 | APE8-dihe-in | -118.31, 128.48 | APE8-rot-in | 304.0 | APE67-dihe-in | -66.76, -18.72 | -40.1, -52.77 | APE12-dist-in | 10.252 | APE11-dist-in | 11.7565 | APE10-dist-in | 5.9964 | APE9-dist-in | 3.9629 | None | None | None | EM | 20.0 | 999.0 | 999.0 | J | 461.0 | 458.0 | 0 | 28 | 28 | 0 | [[13, 271]] | 1.0 | 5u6y | Rattus norvegicus | CAMK_CAMK2A_RAT | CAMK | 5.4e-96 | 327.3 | 1.0 | 256.0 | 256.0 | 155 | 156 | 157 | 159 | 161 | 42 | 60 | 64 | 132 | 134 | 133 | 135.0 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 90 | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| CAMK | CAMK2A | KCC2A_RAT | 5U6YK | P11275 | 13 | 472 | 478.0 | No_ligand | No_ligand | Active | DFGin | 6.8659 | 14.0325 | BLAminus | -131.9, 139.29 | 77.45, 110.86 | -122.02, 32.92 | 286.62, 72.03 | -61.54, -26.54 | in-in | in | 9.311 | Saltbr-in | 2.9304 | HRD-in | -73.15, -44.63 | 73.76, -20.13 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8748 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -148.25, 149.7 | APE9-dihe-na | 143.13, -171.07 | APE8-dihe-in | -118.27, 128.49 | APE8-rot-in | 303.97 | APE67-dihe-in | -66.81, -18.77 | -40.05, -52.72 | APE12-dist-in | 10.2519 | APE11-dist-in | 11.7557 | APE10-dist-in | 5.9964 | APE9-dist-in | 3.9627 | None | None | None | EM | 20.0 | 999.0 | 999.0 | K | 461.0 | 458.0 | 0 | 28 | 28 | 0 | [[13, 271]] | 1.0 | 5u6y | Rattus norvegicus | CAMK_CAMK2A_RAT | CAMK | 5.4e-96 | 327.3 | 1.0 | 256.0 | 256.0 | 155 | 156 | 157 | 159 | 161 | 42 | 60 | 64 | 132 | 134 | 133 | 135.0 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 90 | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| CAMK | CAMK2A | KCC2A_RAT | 5U6YL | P11275 | 13 | 472 | 478.0 | No_ligand | No_ligand | Active | DFGin | 6.8649 | 14.0311 | BLAminus | -131.92, 139.31 | 77.56, 110.83 | -122.08, 32.9 | 286.66, 71.99 | -61.46, -26.52 | in-in | in | 9.3108 | Saltbr-in | 2.931 | HRD-in | -73.09, -44.69 | 73.91, -20.23 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8753 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -148.24, 149.66 | APE9-dihe-na | 143.13, -170.99 | APE8-dihe-in | -118.31, 128.48 | APE8-rot-in | 303.97 | APE67-dihe-in | -66.81, -18.73 | -40.08, -52.69 | APE12-dist-in | 10.2518 | APE11-dist-in | 11.7549 | APE10-dist-in | 5.9952 | APE9-dist-in | 3.9638 | None | None | None | EM | 20.0 | 999.0 | 999.0 | L | 461.0 | 458.0 | 0 | 28 | 28 | 0 | [[13, 271]] | 1.0 | 5u6y | Rattus norvegicus | CAMK_CAMK2A_RAT | CAMK | 5.4e-96 | 327.3 | 1.0 | 256.0 | 256.0 | 155 | 156 | 157 | 159 | 161 | 42 | 60 | 64 | 132 | 134 | 133 | 135.0 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 90 | Calcium/calmodulin-dependent protein kinase type II subunit alpha |