PDB: 5TQ6 — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 5TQ6A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 5TQ6A O60674 843 1132 1132.0 7GV:4000 Type1 Inactive DFGin 6.0752 13.3834 ABAminus -115.84, 4.11 -150.06, 142.11 -129.75, 33.22 297.27, 97.82 -62.11, -22.89 in-in in 8.508 Saltbr-in 2.5838 HRD-in -72.1, -52.07 80.22, -10.44 in-in-none SNCiin in-none ActLoopNT-in 2.8444 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 149.94 APE9-dihe-in -125.18, 149.33 APE8-dihe-in -73.55, 68.75 APE8-rot-na 30.87 APE67-dihe-in -75.64, -0.92 -63.35, -28.23 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 13.0549 APE9-dist-in 7.9296 M1073S,F1076T PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.06 0.259 0.289 A 304.0 276.0 14 31 28 3 [[545, 807], [849, 1125]] 2.0 5tq6 TYR_JAK2-2_HUMAN TYR 6.6e-87 297.1 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5TQ6B O60674 843 1130 1132.0 7GV:4001 Type1 Inactive DFGin 6.1615 13.3628 ABAminus -111.57, -0.99 -147.24, 140.21 -133.48, 34.47 301.56, 87.04 -70.04, -26.0 in-in in 8.4016 Saltbr-in 2.8596 HRD-in -64.79, -51.16 74.89, -3.31 in-in-none SNCiin in-none ActLoopNT-in 2.6843 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 134.65 APE8-dihe-in -75.33, 63.27 APE8-rot-na 30.25 APE67-dihe-in -71.69, -0.6 -52.05, -37.13 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.9648 M1073S,F1076T PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.06 0.259 0.289 B 304.0 273.0 15 31 27 4 [[545, 807], [849, 1125]] 2.0 5tq6 TYR_JAK2-2_HUMAN TYR 6.6e-87 297.1 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 5TQ6 — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 5TQ6A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 5TQ6A O60674 843 1132 1132.0 7GV:4000 Type1 Inactive DFGin 6.0752 13.3834 ABAminus -115.84, 4.11 -150.06, 142.11 -129.75, 33.22 297.27, 97.82 -62.11, -22.89 in-in in 8.508 Saltbr-in 2.5838 HRD-in -72.1, -52.07 80.22, -10.44 in-in-none SNCiin in-none ActLoopNT-in 2.8444 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 149.94 APE9-dihe-in -125.18, 149.33 APE8-dihe-in -73.55, 68.75 APE8-rot-na 30.87 APE67-dihe-in -75.64, -0.92 -63.35, -28.23 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 13.0549 APE9-dist-in 7.9296 M1073S,F1076T PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.06 0.259 0.289 A 304.0 276.0 14 31 28 3 [[545, 807], [849, 1125]] 2.0 5tq6 Homo sapiens TYR_JAK2-2_HUMAN TYR 6.6e-87 297.1 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5TQ6B O60674 843 1130 1132.0 7GV:4001 Type1 Inactive DFGin 6.1615 13.3628 ABAminus -111.57, -0.99 -147.24, 140.21 -133.48, 34.47 301.56, 87.04 -70.04, -26.0 in-in in 8.4016 Saltbr-in 2.8596 HRD-in -64.79, -51.16 74.89, -3.31 in-in-none SNCiin in-none ActLoopNT-in 2.6843 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 134.65 APE8-dihe-in -75.33, 63.27 APE8-rot-na 30.25 APE67-dihe-in -71.69, -0.6 -52.05, -37.13 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.9648 M1073S,F1076T PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.06 0.259 0.289 B 304.0 273.0 15 31 27 4 [[545, 807], [849, 1125]] 2.0 5tq6 Homo sapiens TYR_JAK2-2_HUMAN TYR 6.6e-87 297.1 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 5TQ6 — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name