PDB: 5TQ3 — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 5TQ3B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 5TQ3A O60674 843 1132 1132.0 7GZ:4000 Type1.5_Back Inactive DFGin 6.7366 14.7991 None 172.87, 131.46 -138.34, 98.39 -97.83, 27.37 287.51, 86.01 -80.9, -8.4 in-in in 8.5838 Saltbr-in 2.8363 HRD-in -60.87, -46.98 70.99, 1.64 in-in-in SNCiii in-in ActLoopNT-in 2.9485 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -118.52, 122.1 APE9-dihe-in -107.12, 143.94 APE8-dihe-in -76.54, 73.52 APE8-rot-na 28.78 APE67-dihe-in -71.43, -5.04 -57.67, -36.56 APE12-dist-na 9.1516 APE11-dist-na 10.6276 APE10-dist-na 11.3857 APE9-dist-in 7.3259 M1073S,F1076T,I1126V PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.69 0.219 0.271 A 304.0 284.0 6 31 29 2 [[545, 807], [849, 1125]] 2.0 5tq3 TYR_JAK2-2_HUMAN TYR 6.6e-87 297.1 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5TQ3B O60674 843 1132 1132.0 7GZ:4001 Type1.5_Back Inactive DFGin 6.7371 14.7977 None 175.33, 157.26 -141.41, 99.71 -97.33, 27.05 288.19, 85.47 -80.15, -9.61 in-in in 8.5742 Saltbr-in 2.8801 HRD-in -62.69, -46.43 69.37, 2.93 in-in-in SNCiii in-in ActLoopNT-in 2.9552 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -75.61, 127.26 APE9-dihe-in -88.47, 146.55 APE8-dihe-in -72.07, 80.22 APE8-rot-na 34.9 APE67-dihe-in -69.96, -5.59 -60.36, -37.68 APE12-dist-na 12.1436 APE11-dist-na 10.8771 APE10-dist-na 11.8755 APE9-dist-in 7.1992 M1073S,F1076T,I1126V PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.69 0.219 0.271 B 304.0 287.0 3 31 31 0 [[545, 807], [849, 1125]] 2.0 5tq3 TYR_JAK2-2_HUMAN TYR 6.6e-87 297.1 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 5TQ3 — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 5TQ3B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 5TQ3A O60674 843 1132 1132.0 7GZ:4000 Type1.5_Back Inactive DFGin 6.7366 14.7991 None 172.87, 131.46 -138.34, 98.39 -97.83, 27.37 287.51, 86.01 -80.9, -8.4 in-in in 8.5838 Saltbr-in 2.8363 HRD-in -60.87, -46.98 70.99, 1.64 in-in-in SNCiii in-in ActLoopNT-in 2.9485 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -118.52, 122.1 APE9-dihe-in -107.12, 143.94 APE8-dihe-in -76.54, 73.52 APE8-rot-na 28.78 APE67-dihe-in -71.43, -5.04 -57.67, -36.56 APE12-dist-na 9.1516 APE11-dist-na 10.6276 APE10-dist-na 11.3857 APE9-dist-in 7.3259 M1073S,F1076T,I1126V PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.69 0.219 0.271 A 304.0 284.0 6 31 29 2 [[545, 807], [849, 1125]] 2.0 5tq3 Homo sapiens TYR_JAK2-2_HUMAN TYR 6.6e-87 297.1 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5TQ3B O60674 843 1132 1132.0 7GZ:4001 Type1.5_Back Inactive DFGin 6.7371 14.7977 None 175.33, 157.26 -141.41, 99.71 -97.33, 27.05 288.19, 85.47 -80.15, -9.61 in-in in 8.5742 Saltbr-in 2.8801 HRD-in -62.69, -46.43 69.37, 2.93 in-in-in SNCiii in-in ActLoopNT-in 2.9552 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -75.61, 127.26 APE9-dihe-in -88.47, 146.55 APE8-dihe-in -72.07, 80.22 APE8-rot-na 34.9 APE67-dihe-in -69.96, -5.59 -60.36, -37.68 APE12-dist-na 12.1436 APE11-dist-na 10.8771 APE10-dist-na 11.8755 APE9-dist-in 7.1992 M1073S,F1076T,I1126V PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.69 0.219 0.271 B 304.0 287.0 3 31 31 0 [[545, 807], [849, 1125]] 2.0 5tq3 Homo sapiens TYR_JAK2-2_HUMAN TYR 6.6e-87 297.1 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 5TQ3 — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name