PDB: 5S9K — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S9KB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S9KA Q04771 201 499 509.0 LU8:501,LU8:507,LU8:508 Type1,Allosteric,Allosteric Inactive DFGin 8.3518 13.3497 BLAminus -119.09, 162.43 73.95, 91.92 -101.37, 24.48 300.38, 179.39 -71.09, -13.1 in-out in 9.3128 Saltbr-out 6.1587 HRD-in -79.72, -52.91 78.84, -1.65 out-in-out SNCoio in-out ActLoopNT-in 2.9269 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -122.92, 173.99 APE9-dihe-na -63.97, 163.84 APE8-dihe-in -62.03, 121.91 APE8-rot-in 301.87 APE67-dihe-in -54.23, -35.11 -55.21, -43.69 APE12-dist-none 999.0 APE11-dist-out 6.3795 APE10-dist-out 9.1471 APE9-dist-in 3.5222 Q207D None None XRAY 1.35 0.176 0.2 A 301.0 281.0 18 32 19 13 [[207, 497]] 1.0 5s9k TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S9KB Q04771 205 499 509.0 LU8:501,YV4:505 Type1,Type3 Inactive DFGin 6.8994 13.3113 BLAminus -124.0, 163.62 77.74, 89.17 -103.64, 24.26 305.37, 1.01 -72.01, -17.07 in-out in 8.8119 Saltbr-out 4.6602 HRD-in -80.23, -51.12 77.76, -2.54 out-in-out SNCoio in-out ActLoopNT-in 2.9224 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -118.95, 165.67 APE9-dihe-na -60.95, 168.37 APE8-dihe-in -63.37, 128.29 APE8-rot-in 299.42 APE67-dihe-in -54.29, -31.02 -58.7, -45.73 APE12-dist-in 10.3307 APE11-dist-out 6.1855 APE10-dist-out 8.9921 APE9-dist-in 3.6866 Q207D None None XRAY 1.35 0.176 0.2 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s9k TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S9K — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S9KB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S9KA Q04771 201 499 509.0 LU8:501,LU8:507,LU8:508 Type1,Allosteric,Allosteric Inactive DFGin 8.3518 13.3497 BLAminus -119.09, 162.43 73.95, 91.92 -101.37, 24.48 300.38, 179.39 -71.09, -13.1 in-out in 9.3128 Saltbr-out 6.1587 HRD-in -79.72, -52.91 78.84, -1.65 out-in-out SNCoio in-out ActLoopNT-in 2.9269 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -122.92, 173.99 APE9-dihe-na -63.97, 163.84 APE8-dihe-in -62.03, 121.91 APE8-rot-in 301.87 APE67-dihe-in -54.23, -35.11 -55.21, -43.69 APE12-dist-none 999.0 APE11-dist-out 6.3795 APE10-dist-out 9.1471 APE9-dist-in 3.5222 Q207D None None XRAY 1.35 0.176 0.2 A 301.0 281.0 18 32 19 13 [[207, 497]] 1.0 5s9k Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S9KB Q04771 205 499 509.0 LU8:501,YV4:505 Type1,Type3 Inactive DFGin 6.8994 13.3113 BLAminus -124.0, 163.62 77.74, 89.17 -103.64, 24.26 305.37, 1.01 -72.01, -17.07 in-out in 8.8119 Saltbr-out 4.6602 HRD-in -80.23, -51.12 77.76, -2.54 out-in-out SNCoio in-out ActLoopNT-in 2.9224 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -118.95, 165.67 APE9-dihe-na -60.95, 168.37 APE8-dihe-in -63.37, 128.29 APE8-rot-in 299.42 APE67-dihe-in -54.29, -31.02 -58.7, -45.73 APE12-dist-in 10.3307 APE11-dist-out 6.1855 APE10-dist-out 8.9921 APE9-dist-in 3.6866 Q207D None None XRAY 1.35 0.176 0.2 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s9k Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S9K — TKL ACVR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name