PDB: 5S8B — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S8BB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S8BB Q04771 205 499 509.0 LU8:501,XFV:505,XFV:506,XFV:507 Type1,Allosteric,Allosteric,Allosteric Inactive DFGin 6.8865 13.2682 BLAminus -123.76, 160.92 77.33, 89.17 -99.67, 18.5 303.55, 1.64 -66.62, -18.66 in-out in 8.6237 Saltbr-out 4.5819 HRD-in -80.97, -53.82 77.81, 1.71 out-in-out SNCoio in-out ActLoopNT-in 2.8434 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -120.23, 169.28 APE9-dihe-na -63.35, 164.6 APE8-dihe-in -57.58, 127.02 APE8-rot-in 306.31 APE67-dihe-in -56.16, -27.82 -54.33, -48.01 APE12-dist-in 10.2869 APE11-dist-out 6.129 APE10-dist-out 8.9433 APE9-dist-in 3.7756 Q207D None None XRAY 1.64 0.2 0.233 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s8b TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S8BA Q04771 201 499 509.0 LU8:501,LU8:507,LU8:508,XFV:509,XFV:510,XFV:511,XFV:512 Type1,Allosteric,Allosteric,Allosteric,Allosteric,Allosteric,Allosteric Inactive DFGin 8.3245 13.2716 BLAminus -118.75, 157.39 80.5, 89.5 -103.48, 23.68 297.02, 5.33 -69.81, -17.79 in-out in 9.013 Saltbr-out 5.9816 HRD-in -76.49, -52.01 73.71, 3.51 out-in-out SNCoio in-out ActLoopNT-in 2.8648 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -132.81, 169.84 APE9-dihe-na -47.57, 153.77 APE8-dihe-in -59.87, 123.35 APE8-rot-in 304.85 APE67-dihe-in -51.72, -35.23 -61.3, -40.47 APE12-dist-none 999.0 APE11-dist-out 6.4138 APE10-dist-out 8.8102 APE9-dist-in 3.6992 Q207D None None XRAY 1.64 0.2 0.233 A 301.0 284.0 15 32 19 13 [[207, 497]] 1.0 5s8b TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S8B — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S8BB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S8BB Q04771 205 499 509.0 LU8:501,XFV:505,XFV:506,XFV:507 Type1,Allosteric,Allosteric,Allosteric Inactive DFGin 6.8865 13.2682 BLAminus -123.76, 160.92 77.33, 89.17 -99.67, 18.5 303.55, 1.64 -66.62, -18.66 in-out in 8.6237 Saltbr-out 4.5819 HRD-in -80.97, -53.82 77.81, 1.71 out-in-out SNCoio in-out ActLoopNT-in 2.8434 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -120.23, 169.28 APE9-dihe-na -63.35, 164.6 APE8-dihe-in -57.58, 127.02 APE8-rot-in 306.31 APE67-dihe-in -56.16, -27.82 -54.33, -48.01 APE12-dist-in 10.2869 APE11-dist-out 6.129 APE10-dist-out 8.9433 APE9-dist-in 3.7756 Q207D None None XRAY 1.64 0.2 0.233 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s8b Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S8BA Q04771 201 499 509.0 LU8:501,LU8:507,LU8:508,XFV:509,XFV:510,XFV:511,XFV:512 Type1,Allosteric,Allosteric,Allosteric,Allosteric,Allosteric,Allosteric Inactive DFGin 8.3245 13.2716 BLAminus -118.75, 157.39 80.5, 89.5 -103.48, 23.68 297.02, 5.33 -69.81, -17.79 in-out in 9.013 Saltbr-out 5.9816 HRD-in -76.49, -52.01 73.71, 3.51 out-in-out SNCoio in-out ActLoopNT-in 2.8648 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -132.81, 169.84 APE9-dihe-na -47.57, 153.77 APE8-dihe-in -59.87, 123.35 APE8-rot-in 304.85 APE67-dihe-in -51.72, -35.23 -61.3, -40.47 APE12-dist-none 999.0 APE11-dist-out 6.4138 APE10-dist-out 8.8102 APE9-dist-in 3.6992 Q207D None None XRAY 1.64 0.2 0.233 A 301.0 284.0 15 32 19 13 [[207, 497]] 1.0 5s8b Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S8B — TKL ACVR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name