PDB: 5S89 — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S89B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S89B Q04771 205 499 509.0 LU8:501 Type1 Inactive DFGin 6.984 13.3612 BLAminus -124.97, 163.75 76.76, 88.69 -102.06, 21.8 303.74, 177.29 -68.27, -19.19 in-out in 8.8655 Saltbr-out 4.7724 HRD-in -81.65, -52.32 78.48, -1.17 out-in-out SNCoio in-out ActLoopNT-in 2.9216 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -117.77, 165.98 APE9-dihe-na -60.57, 167.11 APE8-dihe-in -63.21, 128.67 APE8-rot-in 299.1 APE67-dihe-in -57.43, -30.6 -61.18, -42.41 APE12-dist-in 10.2763 APE11-dist-out 6.1981 APE10-dist-out 8.9916 APE9-dist-in 3.7099 Q207D None None XRAY 1.3 0.156 0.174 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s89 TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S89A Q04771 202 499 509.0 LU8:501,LU8:507,LU8:508,XKV:509 Type1,Allosteric,Allosteric,Allosteric Inactive DFGin 8.3474 13.3769 BLAminus -121.17, 161.16 76.55, 91.35 -102.29, 27.94 301.32, 178.72 -70.17, -17.75 in-out in 9.3272 Saltbr-out 6.1807 HRD-in -77.92, -53.6 79.17, 0.85 out-in-out SNCoio in-out ActLoopNT-in 2.9289 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -120.5, 170.79 APE9-dihe-na -62.09, 168.52 APE8-dihe-in -64.51, 125.09 APE8-rot-in 300.94 APE67-dihe-in -58.18, -30.47 -62.43, -38.68 APE12-dist-none 999.0 APE11-dist-out 6.222 APE10-dist-out 9.1355 APE9-dist-in 3.6114 Q207D None None XRAY 1.3 0.156 0.174 A 301.0 283.0 15 32 19 13 [[207, 497]] 1.0 5s89 TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S89 — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S89B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S89B Q04771 205 499 509.0 LU8:501 Type1 Inactive DFGin 6.984 13.3612 BLAminus -124.97, 163.75 76.76, 88.69 -102.06, 21.8 303.74, 177.29 -68.27, -19.19 in-out in 8.8655 Saltbr-out 4.7724 HRD-in -81.65, -52.32 78.48, -1.17 out-in-out SNCoio in-out ActLoopNT-in 2.9216 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -117.77, 165.98 APE9-dihe-na -60.57, 167.11 APE8-dihe-in -63.21, 128.67 APE8-rot-in 299.1 APE67-dihe-in -57.43, -30.6 -61.18, -42.41 APE12-dist-in 10.2763 APE11-dist-out 6.1981 APE10-dist-out 8.9916 APE9-dist-in 3.7099 Q207D None None XRAY 1.3 0.156 0.174 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s89 Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S89A Q04771 202 499 509.0 LU8:501,LU8:507,LU8:508,XKV:509 Type1,Allosteric,Allosteric,Allosteric Inactive DFGin 8.3474 13.3769 BLAminus -121.17, 161.16 76.55, 91.35 -102.29, 27.94 301.32, 178.72 -70.17, -17.75 in-out in 9.3272 Saltbr-out 6.1807 HRD-in -77.92, -53.6 79.17, 0.85 out-in-out SNCoio in-out ActLoopNT-in 2.9289 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -120.5, 170.79 APE9-dihe-na -62.09, 168.52 APE8-dihe-in -64.51, 125.09 APE8-rot-in 300.94 APE67-dihe-in -58.18, -30.47 -62.43, -38.68 APE12-dist-none 999.0 APE11-dist-out 6.222 APE10-dist-out 9.1355 APE9-dist-in 3.6114 Q207D None None XRAY 1.3 0.156 0.174 A 301.0 283.0 15 32 19 13 [[207, 497]] 1.0 5s89 Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S89 — TKL ACVR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name