PDB: 5S86 — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S86B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S86B Q04771 205 499 509.0 LU8:501,XK7:505 Type1,Allosteric Inactive DFGin 6.9997 13.343 BLAminus -124.78, 165.07 76.1, 88.35 -101.51, 22.18 301.71, 177.78 -69.78, -18.41 in-out in 8.8877 Saltbr-out 4.7455 HRD-in -81.45, -50.76 76.49, -0.86 out-in-in SNCoii in-in ActLoopNT-in 2.9308 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -113.0, 158.9 APE9-dihe-na 111.5, 158.23 APE8-dihe-in -70.2, 127.65 APE8-rot-in 298.18 APE67-dihe-in -59.26, -28.16 -59.39, -41.48 APE12-dist-in 11.6278 APE11-dist-in 12.2182 APE10-dist-in 6.6711 APE9-dist-in 3.6866 Q207D None None XRAY 1.31 0.169 0.19 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s86 TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S86A Q04771 202 499 509.0 LU8:501,LU8:507,LU8:508,XK7:509 Type1,Allosteric,Allosteric,Allosteric Inactive DFGin 8.3538 13.3046 BLAminus -123.41, 163.19 74.35, 90.8 -102.12, 25.57 300.77, 178.94 -68.55, -18.48 in-out in 9.3264 Saltbr-out 6.0597 HRD-in -80.27, -53.89 78.04, 1.57 out-in-out SNCoio in-out ActLoopNT-in 2.9287 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -123.39, 173.24 APE9-dihe-na -67.68, 166.72 APE8-dihe-in -62.8, 124.74 APE8-rot-in 300.74 APE67-dihe-in -57.85, -29.86 -60.17, -41.27 APE12-dist-none 999.0 APE11-dist-out 6.4584 APE10-dist-out 9.1419 APE9-dist-in 3.5121 Q207D None None XRAY 1.31 0.169 0.19 A 301.0 283.0 15 32 19 13 [[207, 497]] 1.0 5s86 TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S86 — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S86B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S86B Q04771 205 499 509.0 LU8:501,XK7:505 Type1,Allosteric Inactive DFGin 6.9997 13.343 BLAminus -124.78, 165.07 76.1, 88.35 -101.51, 22.18 301.71, 177.78 -69.78, -18.41 in-out in 8.8877 Saltbr-out 4.7455 HRD-in -81.45, -50.76 76.49, -0.86 out-in-in SNCoii in-in ActLoopNT-in 2.9308 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -113.0, 158.9 APE9-dihe-na 111.5, 158.23 APE8-dihe-in -70.2, 127.65 APE8-rot-in 298.18 APE67-dihe-in -59.26, -28.16 -59.39, -41.48 APE12-dist-in 11.6278 APE11-dist-in 12.2182 APE10-dist-in 6.6711 APE9-dist-in 3.6866 Q207D None None XRAY 1.31 0.169 0.19 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s86 Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S86A Q04771 202 499 509.0 LU8:501,LU8:507,LU8:508,XK7:509 Type1,Allosteric,Allosteric,Allosteric Inactive DFGin 8.3538 13.3046 BLAminus -123.41, 163.19 74.35, 90.8 -102.12, 25.57 300.77, 178.94 -68.55, -18.48 in-out in 9.3264 Saltbr-out 6.0597 HRD-in -80.27, -53.89 78.04, 1.57 out-in-out SNCoio in-out ActLoopNT-in 2.9287 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -123.39, 173.24 APE9-dihe-na -67.68, 166.72 APE8-dihe-in -62.8, 124.74 APE8-rot-in 300.74 APE67-dihe-in -57.85, -29.86 -60.17, -41.27 APE12-dist-none 999.0 APE11-dist-out 6.4584 APE10-dist-out 9.1419 APE9-dist-in 3.5121 Q207D None None XRAY 1.31 0.169 0.19 A 301.0 283.0 15 32 19 13 [[207, 497]] 1.0 5s86 Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S86 — TKL ACVR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name