PDB: 5S82 — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S82B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S82B Q04771 205 499 509.0 LU8:501,LAC:505 Type1,Allosteric Inactive DFGin 6.6555 13.3978 BLAminus -126.04, 165.16 75.17, 84.42 -92.96, 20.32 298.14, 1.79 -72.8, -17.41 in-out in 8.9053 Saltbr-out 4.4972 HRD-in -74.85, -51.79 76.63, 2.28 out-in-in SNCoii in-in ActLoopNT-in 2.8295 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -116.55, 160.28 APE9-dihe-na 116.12, -172.15 APE8-dihe-in -92.31, 127.42 APE8-rot-in 312.53 APE67-dihe-in -58.12, -32.21 -55.48, -45.17 APE12-dist-in 11.3772 APE11-dist-in 12.1036 APE10-dist-in 6.2531 APE9-dist-in 3.7924 Q207D None None XRAY 1.71 0.211 0.253 B 301.0 284.0 11 32 25 7 [[207, 497]] 1.0 5s82 TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S82A Q04771 202 499 509.0 LU8:501,LU8:507,LU8:508 Type1,Allosteric,Allosteric Inactive DFGin 8.468 13.2543 BLAminus -122.58, 165.4 75.09, 85.58 -98.64, 22.96 294.39, 0.35 -56.95, -25.74 in-out in 9.3363 Saltbr-out 5.524 HRD-in -76.5, -58.03 77.63, 6.82 out-in-none SNCoin in-none ActLoopNT-in 2.8593 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_niii APE10-dihe-na -106.37, 156.71 APE9-dihe-na 110.11, -167.89 APE8-dihe-in -91.26, 123.24 APE8-rot-in 309.79 APE67-dihe-in -54.4, -31.68 -54.65, -45.23 APE12-dist-none 999.0 APE11-dist-in 10.8938 APE10-dist-in 6.4362 APE9-dist-in 3.9819 Q207D None None XRAY 1.71 0.211 0.253 A 301.0 279.0 19 32 19 13 [[207, 497]] 1.0 5s82 TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S82 — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S82B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S82B Q04771 205 499 509.0 LU8:501,LAC:505 Type1,Allosteric Inactive DFGin 6.6555 13.3978 BLAminus -126.04, 165.16 75.17, 84.42 -92.96, 20.32 298.14, 1.79 -72.8, -17.41 in-out in 8.9053 Saltbr-out 4.4972 HRD-in -74.85, -51.79 76.63, 2.28 out-in-in SNCoii in-in ActLoopNT-in 2.8295 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -116.55, 160.28 APE9-dihe-na 116.12, -172.15 APE8-dihe-in -92.31, 127.42 APE8-rot-in 312.53 APE67-dihe-in -58.12, -32.21 -55.48, -45.17 APE12-dist-in 11.3772 APE11-dist-in 12.1036 APE10-dist-in 6.2531 APE9-dist-in 3.7924 Q207D None None XRAY 1.71 0.211 0.253 B 301.0 284.0 11 32 25 7 [[207, 497]] 1.0 5s82 Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S82A Q04771 202 499 509.0 LU8:501,LU8:507,LU8:508 Type1,Allosteric,Allosteric Inactive DFGin 8.468 13.2543 BLAminus -122.58, 165.4 75.09, 85.58 -98.64, 22.96 294.39, 0.35 -56.95, -25.74 in-out in 9.3363 Saltbr-out 5.524 HRD-in -76.5, -58.03 77.63, 6.82 out-in-none SNCoin in-none ActLoopNT-in 2.8593 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_niii APE10-dihe-na -106.37, 156.71 APE9-dihe-na 110.11, -167.89 APE8-dihe-in -91.26, 123.24 APE8-rot-in 309.79 APE67-dihe-in -54.4, -31.68 -54.65, -45.23 APE12-dist-none 999.0 APE11-dist-in 10.8938 APE10-dist-in 6.4362 APE9-dist-in 3.9819 Q207D None None XRAY 1.71 0.211 0.253 A 301.0 279.0 19 32 19 13 [[207, 497]] 1.0 5s82 Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S82 — TKL ACVR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name