PDB: 5S81 — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S81B
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S81B Q04771 208 499 509.0 LU8:501,XJV:505,XJV:506,XJV:507,XJV:508 Type1,Allosteric,Allosteric,Allosteric,Allosteric Inactive DFGin 7.098 13.469 BLAminus -122.8, 162.49 76.01, 87.95 -102.27, 24.4 302.62, 170.08 -70.81, -17.85 in-out in 8.791 Saltbr-out 4.612 HRD-in -80.16, -52.27 79.27, -5.04 out-in-out SNCoio in-out ActLoopNT-in 2.944 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -122.12, 164.98 APE9-dihe-na -61.51, 162.25 APE8-dihe-in -57.76, 127.22 APE8-rot-in 301.4 APE67-dihe-in -60.84, -27.37 -62.01, -41.07 APE12-dist-in 10.36 APE11-dist-out 6.197 APE10-dist-out 8.99 APE9-dist-in 3.889 Q207D None None XRAY 1.43 0.17 0.196 B 301 289 3 0 0 0 [[207, 497]] 1.0 5s81 TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2 267 266 353 354 355 357 359 235 248 252 333 335 334 336 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S81A Q04771 202 499 509.0 LU8:501,LU8:508,LU8:509,XJV:510,XJV:511 Type1,Allosteric,Allosteric,Allosteric,Type1 Inactive DFGin 8.317 13.29 BLAminus -119.91, 161.36 74.15, 90.65 -102.16, 24.41 299.52, 0.73 -66.2, -16.75 in-out in 9.161 Saltbr-out 6.217 HRD-in -73.39, -56.79 82.29, -0.98 out-in-out SNCoio in-out ActLoopNT-in 2.905 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -125.7, 171.05 APE9-dihe-na -60.67, 164.13 APE8-dihe-in -64.52, 125.11 APE8-rot-in 304.88 APE67-dihe-in -56.55, -33.14 -61.08, -40.13 APE12-dist-none 999.0 APE11-dist-out 6.189 APE10-dist-out 8.862 APE9-dist-in 3.68 Q207D None None XRAY 1.43 0.17 0.196 A 301 283 15 0 0 13 [[207, 497]] 1.0 5s81 TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2 267 266 353 354 355 357 359 235 248 252 333 335 334 336 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S81 — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S81B
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S81B Q04771 208 499 509.0 LU8:501,XJV:505,XJV:506,XJV:507,XJV:508 Type1,Allosteric,Allosteric,Allosteric,Allosteric Inactive DFGin 7.098 13.469 BLAminus -122.8, 162.49 76.01, 87.95 -102.27, 24.4 302.62, 170.08 -70.81, -17.85 in-out in 8.791 Saltbr-out 4.612 HRD-in -80.16, -52.27 79.27, -5.04 out-in-out SNCoio in-out ActLoopNT-in 2.944 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -122.12, 164.98 APE9-dihe-na -61.51, 162.25 APE8-dihe-in -57.76, 127.22 APE8-rot-in 301.4 APE67-dihe-in -60.84, -27.37 -62.01, -41.07 APE12-dist-in 10.36 APE11-dist-out 6.197 APE10-dist-out 8.99 APE9-dist-in 3.889 Q207D None None XRAY 1.43 0.17 0.196 B 301 289 3 0 0 0 [[207, 497]] 1.0 5s81 Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2 267 266 353 354 355 357 359 235 248 252 333 335 334 336 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S81A Q04771 202 499 509.0 LU8:501,LU8:508,LU8:509,XJV:510,XJV:511 Type1,Allosteric,Allosteric,Allosteric,Type1 Inactive DFGin 8.317 13.29 BLAminus -119.91, 161.36 74.15, 90.65 -102.16, 24.41 299.52, 0.73 -66.2, -16.75 in-out in 9.161 Saltbr-out 6.217 HRD-in -73.39, -56.79 82.29, -0.98 out-in-out SNCoio in-out ActLoopNT-in 2.905 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -125.7, 171.05 APE9-dihe-na -60.67, 164.13 APE8-dihe-in -64.52, 125.11 APE8-rot-in 304.88 APE67-dihe-in -56.55, -33.14 -61.08, -40.13 APE12-dist-none 999.0 APE11-dist-out 6.189 APE10-dist-out 8.862 APE9-dist-in 3.68 Q207D None None XRAY 1.43 0.17 0.196 A 301 283 15 0 0 13 [[207, 497]] 1.0 5s81 Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2 267 266 353 354 355 357 359 235 248 252 333 335 334 336 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S81 — TKL ACVR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name