PDB: 5S80 — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S80B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S80A Q04771 202 499 509.0 LU8:501,LU8:508,LU8:509 Type1,Allosteric,Allosteric Inactive DFGin 8.3137 13.3058 BLAminus -112.55, 159.81 78.34, 88.26 -99.06, 22.42 300.25, 0.46 -63.75, -19.98 in-out in 9.0251 Saltbr-out 5.8825 HRD-in -76.34, -54.31 74.73, 2.06 out-in-out SNCoio in-out ActLoopNT-in 2.9057 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -128.9, 168.55 APE9-dihe-na -54.89, 157.92 APE8-dihe-in -57.52, 122.86 APE8-rot-in 308.47 APE67-dihe-in -52.78, -30.68 -62.36, -41.16 APE12-dist-none 999.0 APE11-dist-out 6.1425 APE10-dist-out 8.7825 APE9-dist-in 3.7345 Q207D None None XRAY 1.67 0.197 0.231 A 301.0 283.0 15 32 19 13 [[207, 497]] 1.0 5s80 TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S80B Q04771 205 499 509.0 LU8:501,XGM:505,XGM:506 Type1,Allosteric,Allosteric Inactive DFGin 7.0267 13.5533 BLAminus -130.83, 163.29 75.8, 86.12 -98.93, 18.93 301.48, 172.59 -65.51, -18.83 in-out in 8.9692 Saltbr-out 4.718 HRD-in -78.19, -55.2 81.16, -3.45 out-in-out SNCoio in-out ActLoopNT-in 2.8547 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -122.24, 160.71 APE9-dihe-na -59.43, 165.2 APE8-dihe-in -58.98, 127.47 APE8-rot-in 308.35 APE67-dihe-in -58.04, -28.7 -56.74, -44.6 APE12-dist-in 10.4101 APE11-dist-out 6.1264 APE10-dist-out 9.0862 APE9-dist-in 3.8114 Q207D None None XRAY 1.67 0.197 0.231 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s80 TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S80 — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S80B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S80A Q04771 202 499 509.0 LU8:501,LU8:508,LU8:509 Type1,Allosteric,Allosteric Inactive DFGin 8.3137 13.3058 BLAminus -112.55, 159.81 78.34, 88.26 -99.06, 22.42 300.25, 0.46 -63.75, -19.98 in-out in 9.0251 Saltbr-out 5.8825 HRD-in -76.34, -54.31 74.73, 2.06 out-in-out SNCoio in-out ActLoopNT-in 2.9057 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -128.9, 168.55 APE9-dihe-na -54.89, 157.92 APE8-dihe-in -57.52, 122.86 APE8-rot-in 308.47 APE67-dihe-in -52.78, -30.68 -62.36, -41.16 APE12-dist-none 999.0 APE11-dist-out 6.1425 APE10-dist-out 8.7825 APE9-dist-in 3.7345 Q207D None None XRAY 1.67 0.197 0.231 A 301.0 283.0 15 32 19 13 [[207, 497]] 1.0 5s80 Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S80B Q04771 205 499 509.0 LU8:501,XGM:505,XGM:506 Type1,Allosteric,Allosteric Inactive DFGin 7.0267 13.5533 BLAminus -130.83, 163.29 75.8, 86.12 -98.93, 18.93 301.48, 172.59 -65.51, -18.83 in-out in 8.9692 Saltbr-out 4.718 HRD-in -78.19, -55.2 81.16, -3.45 out-in-out SNCoio in-out ActLoopNT-in 2.8547 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -122.24, 160.71 APE9-dihe-na -59.43, 165.2 APE8-dihe-in -58.98, 127.47 APE8-rot-in 308.35 APE67-dihe-in -58.04, -28.7 -56.74, -44.6 APE12-dist-in 10.4101 APE11-dist-out 6.1264 APE10-dist-out 9.0862 APE9-dist-in 3.8114 Q207D None None XRAY 1.67 0.197 0.231 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s80 Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S80 — TKL ACVR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name