PDB: 5S7Z — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7ZB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7ZB Q04771 205 499 509.0 LU8:501,BYZ:505 Type1,Allosteric Inactive DFGin 6.9632 13.3741 BLAminus -125.8, 161.65 77.14, 88.32 -102.44, 23.35 302.89, 177.91 -73.03, -13.12 in-out in 8.7708 Saltbr-out 4.7211 HRD-in -76.79, -54.43 80.82, -3.64 out-in-out SNCoio in-out ActLoopNT-in 2.9201 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -121.61, 165.38 APE9-dihe-na -60.57, 163.68 APE8-dihe-in -58.84, 127.79 APE8-rot-in 300.37 APE67-dihe-in -58.11, -27.66 -62.19, -41.34 APE12-dist-in 10.3506 APE11-dist-out 6.1474 APE10-dist-out 9.0017 APE9-dist-in 3.8366 Q207D None None XRAY 1.3 0.163 0.184 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s7z TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7ZA Q04771 202 499 509.0 LU8:501,LU8:508,LU8:509,BYZ:510,BYZ:511 Type1,Allosteric,Allosteric,Allosteric,Allosteric Inactive DFGin 8.3715 13.3787 BLAminus -118.29, 164.94 73.01, 90.28 -101.45, 25.18 297.95, 179.49 -66.08, -18.47 in-out in 9.0354 Saltbr-out 5.8164 HRD-in -75.5, -56.61 78.44, 1.56 out-in-out SNCoio in-out ActLoopNT-in 2.884 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -121.97, 169.25 APE9-dihe-na -61.57, 164.92 APE8-dihe-in -63.28, 125.7 APE8-rot-in 303.7 APE67-dihe-in -57.35, -34.69 -61.46, -39.19 APE12-dist-in 10.5839 APE11-dist-out 6.2834 APE10-dist-out 8.9041 APE9-dist-in 3.732 Q207D None None XRAY 1.3 0.163 0.184 A 301.0 287.0 11 32 23 9 [[207, 497]] 1.0 5s7z TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7Z — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7ZB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7ZB Q04771 205 499 509.0 LU8:501,BYZ:505 Type1,Allosteric Inactive DFGin 6.9632 13.3741 BLAminus -125.8, 161.65 77.14, 88.32 -102.44, 23.35 302.89, 177.91 -73.03, -13.12 in-out in 8.7708 Saltbr-out 4.7211 HRD-in -76.79, -54.43 80.82, -3.64 out-in-out SNCoio in-out ActLoopNT-in 2.9201 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -121.61, 165.38 APE9-dihe-na -60.57, 163.68 APE8-dihe-in -58.84, 127.79 APE8-rot-in 300.37 APE67-dihe-in -58.11, -27.66 -62.19, -41.34 APE12-dist-in 10.3506 APE11-dist-out 6.1474 APE10-dist-out 9.0017 APE9-dist-in 3.8366 Q207D None None XRAY 1.3 0.163 0.184 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s7z Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7ZA Q04771 202 499 509.0 LU8:501,LU8:508,LU8:509,BYZ:510,BYZ:511 Type1,Allosteric,Allosteric,Allosteric,Allosteric Inactive DFGin 8.3715 13.3787 BLAminus -118.29, 164.94 73.01, 90.28 -101.45, 25.18 297.95, 179.49 -66.08, -18.47 in-out in 9.0354 Saltbr-out 5.8164 HRD-in -75.5, -56.61 78.44, 1.56 out-in-out SNCoio in-out ActLoopNT-in 2.884 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -121.97, 169.25 APE9-dihe-na -61.57, 164.92 APE8-dihe-in -63.28, 125.7 APE8-rot-in 303.7 APE67-dihe-in -57.35, -34.69 -61.46, -39.19 APE12-dist-in 10.5839 APE11-dist-out 6.2834 APE10-dist-out 8.9041 APE9-dist-in 3.732 Q207D None None XRAY 1.3 0.163 0.184 A 301.0 287.0 11 32 23 9 [[207, 497]] 1.0 5s7z Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7Z — TKL ACVR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name