PDB: 5S7Y — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7YB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7YA Q04771 202 499 509.0 LU8:501,LU8:507,LU8:508 Type1,Allosteric,Allosteric Inactive DFGin 8.3776 13.3431 BLAminus -121.01, 162.15 74.22, 90.85 -101.18, 24.99 303.51, 176.94 -65.0, -19.5 in-out in 9.2462 Saltbr-out 6.2055 HRD-in -79.92, -53.25 77.89, -1.46 out-in-out SNCoio in-out ActLoopNT-in 2.9029 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -125.05, 171.62 APE9-dihe-na -63.16, 165.02 APE8-dihe-in -61.65, 124.26 APE8-rot-in 302.58 APE67-dihe-in -56.65, -33.92 -63.4, -36.98 APE12-dist-none 999.0 APE11-dist-out 6.068 APE10-dist-out 8.8721 APE9-dist-in 3.6119 Q207D None None XRAY 1.37 0.161 0.184 A 301.0 283.0 15 32 19 13 [[207, 497]] 1.0 5s7y TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7YB Q04771 207 499 509.0 LU8:501,XJP:505,XJP:506,XJP:507,XJP:508,XJP:509 Type1,Allosteric,Allosteric,Allosteric,Allosteric,Allosteric Inactive DFGin 7.0154 13.4267 BLAminus -126.98, 162.69 75.57, 89.14 -100.94, 21.08 303.3, 173.42 -67.07, -20.24 in-out in 8.8412 Saltbr-out 4.7344 HRD-in -81.6, -53.06 80.61, -4.28 out-in-out SNCoio in-out ActLoopNT-in 2.9288 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -119.96, 164.75 APE9-dihe-na -61.91, 164.34 APE8-dihe-in -58.26, 128.88 APE8-rot-in 298.27 APE67-dihe-in -57.49, -30.88 -60.34, -41.77 APE12-dist-in 10.3261 APE11-dist-out 6.153 APE10-dist-out 9.0872 APE9-dist-in 3.7656 Q207D None None XRAY 1.37 0.161 0.184 B 301.0 290.0 3 32 32 0 [[207, 497]] 1.0 5s7y TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7Y — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7YB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7YA Q04771 202 499 509.0 LU8:501,LU8:507,LU8:508 Type1,Allosteric,Allosteric Inactive DFGin 8.3776 13.3431 BLAminus -121.01, 162.15 74.22, 90.85 -101.18, 24.99 303.51, 176.94 -65.0, -19.5 in-out in 9.2462 Saltbr-out 6.2055 HRD-in -79.92, -53.25 77.89, -1.46 out-in-out SNCoio in-out ActLoopNT-in 2.9029 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -125.05, 171.62 APE9-dihe-na -63.16, 165.02 APE8-dihe-in -61.65, 124.26 APE8-rot-in 302.58 APE67-dihe-in -56.65, -33.92 -63.4, -36.98 APE12-dist-none 999.0 APE11-dist-out 6.068 APE10-dist-out 8.8721 APE9-dist-in 3.6119 Q207D None None XRAY 1.37 0.161 0.184 A 301.0 283.0 15 32 19 13 [[207, 497]] 1.0 5s7y Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7YB Q04771 207 499 509.0 LU8:501,XJP:505,XJP:506,XJP:507,XJP:508,XJP:509 Type1,Allosteric,Allosteric,Allosteric,Allosteric,Allosteric Inactive DFGin 7.0154 13.4267 BLAminus -126.98, 162.69 75.57, 89.14 -100.94, 21.08 303.3, 173.42 -67.07, -20.24 in-out in 8.8412 Saltbr-out 4.7344 HRD-in -81.6, -53.06 80.61, -4.28 out-in-out SNCoio in-out ActLoopNT-in 2.9288 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -119.96, 164.75 APE9-dihe-na -61.91, 164.34 APE8-dihe-in -58.26, 128.88 APE8-rot-in 298.27 APE67-dihe-in -57.49, -30.88 -60.34, -41.77 APE12-dist-in 10.3261 APE11-dist-out 6.153 APE10-dist-out 9.0872 APE9-dist-in 3.7656 Q207D None None XRAY 1.37 0.161 0.184 B 301.0 290.0 3 32 32 0 [[207, 497]] 1.0 5s7y Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7Y — TKL ACVR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name