PDB: 5S7X — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7XB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7XB Q04771 205 499 509.0 LU8:501,LGA:505 Type1,Allosteric Inactive DFGin 7.0314 13.379 BLAminus -128.0, 163.2 78.06, 89.3 -102.46, 20.69 301.92, 175.18 -69.56, -15.46 in-out in 8.8274 Saltbr-out 4.6398 HRD-in -76.89, -56.14 80.13, -1.68 out-in-out SNCoio in-out ActLoopNT-in 2.9186 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -121.04, 166.03 APE9-dihe-na -61.79, 165.52 APE8-dihe-in -59.06, 127.18 APE8-rot-in 299.22 APE67-dihe-in -59.1, -28.73 -61.83, -40.56 APE12-dist-in 10.3779 APE11-dist-out 6.1653 APE10-dist-out 8.945 APE9-dist-in 3.807 Q207D None None XRAY 1.3 0.151 0.169 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s7x TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7XA Q04771 202 499 509.0 LU8:501,LU8:508,LU8:509,LGA:510 Type1,Allosteric,Allosteric,Allosteric Inactive DFGin 8.365 13.3392 BLAminus -120.33, 161.6 75.96, 90.47 -101.36, 24.64 300.81, 178.23 -69.2, -15.97 in-out in 9.1534 Saltbr-out 6.1306 HRD-in -77.36, -53.88 76.8, 3.92 out-in-out SNCoio in-out ActLoopNT-in 2.9429 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -123.06, 170.39 APE9-dihe-na -62.49, 167.4 APE8-dihe-in -64.84, 124.15 APE8-rot-in 301.78 APE67-dihe-in -56.96, -32.72 -62.72, -36.99 APE12-dist-none 999.0 APE11-dist-out 6.2275 APE10-dist-out 8.8288 APE9-dist-in 3.6624 Q207D None None XRAY 1.3 0.151 0.169 A 301.0 283.0 15 32 19 13 [[207, 497]] 1.0 5s7x TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7X — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7XB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7XB Q04771 205 499 509.0 LU8:501,LGA:505 Type1,Allosteric Inactive DFGin 7.0314 13.379 BLAminus -128.0, 163.2 78.06, 89.3 -102.46, 20.69 301.92, 175.18 -69.56, -15.46 in-out in 8.8274 Saltbr-out 4.6398 HRD-in -76.89, -56.14 80.13, -1.68 out-in-out SNCoio in-out ActLoopNT-in 2.9186 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -121.04, 166.03 APE9-dihe-na -61.79, 165.52 APE8-dihe-in -59.06, 127.18 APE8-rot-in 299.22 APE67-dihe-in -59.1, -28.73 -61.83, -40.56 APE12-dist-in 10.3779 APE11-dist-out 6.1653 APE10-dist-out 8.945 APE9-dist-in 3.807 Q207D None None XRAY 1.3 0.151 0.169 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s7x Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7XA Q04771 202 499 509.0 LU8:501,LU8:508,LU8:509,LGA:510 Type1,Allosteric,Allosteric,Allosteric Inactive DFGin 8.365 13.3392 BLAminus -120.33, 161.6 75.96, 90.47 -101.36, 24.64 300.81, 178.23 -69.2, -15.97 in-out in 9.1534 Saltbr-out 6.1306 HRD-in -77.36, -53.88 76.8, 3.92 out-in-out SNCoio in-out ActLoopNT-in 2.9429 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -123.06, 170.39 APE9-dihe-na -62.49, 167.4 APE8-dihe-in -64.84, 124.15 APE8-rot-in 301.78 APE67-dihe-in -56.96, -32.72 -62.72, -36.99 APE12-dist-none 999.0 APE11-dist-out 6.2275 APE10-dist-out 8.8288 APE9-dist-in 3.6624 Q207D None None XRAY 1.3 0.151 0.169 A 301.0 283.0 15 32 19 13 [[207, 497]] 1.0 5s7x Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7X — TKL ACVR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name