PDB: 5S7W — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7WB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7WB Q04771 205 499 509.0 LU8:501 Type1 Inactive DFGin 7.0298 13.4008 BLAminus -127.76, 159.78 80.36, 85.76 -99.88, 21.09 305.52, 179.19 -65.9, -24.32 in-out in 8.9404 Saltbr-out 4.8194 HRD-in -77.42, -54.04 83.37, -7.62 out-in-out SNCoio in-out ActLoopNT-in 2.9581 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -116.09, 164.43 APE9-dihe-na -60.72, 165.96 APE8-dihe-in -63.25, 128.46 APE8-rot-in 296.55 APE67-dihe-in -59.57, -28.14 -60.1, -41.66 APE12-dist-in 10.3172 APE11-dist-out 6.2471 APE10-dist-out 9.0709 APE9-dist-in 3.8111 Q207D None None XRAY 1.33 0.164 0.186 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s7w TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7WA Q04771 202 499 509.0 LU8:501,LU8:507,LU8:508 Type1,Allosteric,Allosteric Inactive DFGin 8.3816 13.4221 BLAminus -120.63, 163.92 74.5, 89.95 -100.48, 28.03 301.03, 179.86 -70.31, -18.41 in-out in 9.2435 Saltbr-out 6.2008 HRD-in -78.77, -52.99 79.89, -3.2 out-in-out SNCoio in-out ActLoopNT-in 2.9396 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -122.35, 170.12 APE9-dihe-na -61.34, 168.74 APE8-dihe-in -65.88, 124.22 APE8-rot-in 304.99 APE67-dihe-in -56.25, -29.94 -63.21, -38.79 APE12-dist-none 999.0 APE11-dist-out 6.2527 APE10-dist-out 8.9271 APE9-dist-in 3.6958 Q207D None None XRAY 1.33 0.164 0.186 A 301.0 284.0 14 32 19 13 [[207, 497]] 1.0 5s7w TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7W — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7WB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7WB Q04771 205 499 509.0 LU8:501 Type1 Inactive DFGin 7.0298 13.4008 BLAminus -127.76, 159.78 80.36, 85.76 -99.88, 21.09 305.52, 179.19 -65.9, -24.32 in-out in 8.9404 Saltbr-out 4.8194 HRD-in -77.42, -54.04 83.37, -7.62 out-in-out SNCoio in-out ActLoopNT-in 2.9581 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -116.09, 164.43 APE9-dihe-na -60.72, 165.96 APE8-dihe-in -63.25, 128.46 APE8-rot-in 296.55 APE67-dihe-in -59.57, -28.14 -60.1, -41.66 APE12-dist-in 10.3172 APE11-dist-out 6.2471 APE10-dist-out 9.0709 APE9-dist-in 3.8111 Q207D None None XRAY 1.33 0.164 0.186 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s7w Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7WA Q04771 202 499 509.0 LU8:501,LU8:507,LU8:508 Type1,Allosteric,Allosteric Inactive DFGin 8.3816 13.4221 BLAminus -120.63, 163.92 74.5, 89.95 -100.48, 28.03 301.03, 179.86 -70.31, -18.41 in-out in 9.2435 Saltbr-out 6.2008 HRD-in -78.77, -52.99 79.89, -3.2 out-in-out SNCoio in-out ActLoopNT-in 2.9396 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -122.35, 170.12 APE9-dihe-na -61.34, 168.74 APE8-dihe-in -65.88, 124.22 APE8-rot-in 304.99 APE67-dihe-in -56.25, -29.94 -63.21, -38.79 APE12-dist-none 999.0 APE11-dist-out 6.2527 APE10-dist-out 8.9271 APE9-dist-in 3.6958 Q207D None None XRAY 1.33 0.164 0.186 A 301.0 284.0 14 32 19 13 [[207, 497]] 1.0 5s7w Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7W — TKL ACVR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name