PDB: 5S7U — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7UB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7UA Q04771 202 499 509.0 LU8:501,LU8:507,LU8:508 Type1,Allosteric,Allosteric Inactive DFGin 8.3051 13.2129 BLAminus -114.05, 162.83 73.86, 86.44 -96.11, 24.11 301.91, 5.0 -63.32, -18.47 in-out in 9.2232 Saltbr-out 5.6693 HRD-in -78.6, -56.95 81.06, 1.88 out-in-none SNCoin in-none ActLoopNT-in 2.8879 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_niii APE10-dihe-na -102.37, -33.42 APE9-dihe-na -82.13, -169.33 APE8-dihe-in -70.61, 128.02 APE8-rot-in 308.81 APE67-dihe-in -53.65, -30.76 -61.02, -43.28 APE12-dist-none 999.0 APE11-dist-in 10.9037 APE10-dist-in 6.4566 APE9-dist-in 3.6543 Q207D None None XRAY 1.59 0.219 0.261 A 301.0 280.0 18 32 19 13 [[207, 497]] 1.0 5s7u TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7UB Q04771 205 499 509.0 LU8:501,XGY:505,XGY:506 Type1,Allosteric,Allosteric Inactive DFGin 6.6967 13.3542 BLAminus -130.21, 164.61 74.6, 82.7 -94.38, 13.73 305.4, 176.35 -55.24, -22.33 in-out in 8.956 Saltbr-out 4.6866 HRD-in -75.48, -53.06 77.34, -3.38 out-in-out SNCoio in-out ActLoopNT-in 2.8147 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -164.99, 129.38 APE9-dihe-na -126.69, -126.94 APE8-dihe-in -91.63, 124.43 APE8-rot-in 299.73 APE67-dihe-in -58.25, -31.07 -56.39, -48.22 APE12-dist-in 10.8295 APE11-dist-in 11.4695 APE10-dist-out 9.5141 APE9-dist-in 4.0299 Q207D None None XRAY 1.59 0.219 0.261 B 301.0 279.0 16 32 23 9 [[207, 497]] 1.0 5s7u TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7U — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7UB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7UA Q04771 202 499 509.0 LU8:501,LU8:507,LU8:508 Type1,Allosteric,Allosteric Inactive DFGin 8.3051 13.2129 BLAminus -114.05, 162.83 73.86, 86.44 -96.11, 24.11 301.91, 5.0 -63.32, -18.47 in-out in 9.2232 Saltbr-out 5.6693 HRD-in -78.6, -56.95 81.06, 1.88 out-in-none SNCoin in-none ActLoopNT-in 2.8879 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_niii APE10-dihe-na -102.37, -33.42 APE9-dihe-na -82.13, -169.33 APE8-dihe-in -70.61, 128.02 APE8-rot-in 308.81 APE67-dihe-in -53.65, -30.76 -61.02, -43.28 APE12-dist-none 999.0 APE11-dist-in 10.9037 APE10-dist-in 6.4566 APE9-dist-in 3.6543 Q207D None None XRAY 1.59 0.219 0.261 A 301.0 280.0 18 32 19 13 [[207, 497]] 1.0 5s7u Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7UB Q04771 205 499 509.0 LU8:501,XGY:505,XGY:506 Type1,Allosteric,Allosteric Inactive DFGin 6.6967 13.3542 BLAminus -130.21, 164.61 74.6, 82.7 -94.38, 13.73 305.4, 176.35 -55.24, -22.33 in-out in 8.956 Saltbr-out 4.6866 HRD-in -75.48, -53.06 77.34, -3.38 out-in-out SNCoio in-out ActLoopNT-in 2.8147 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -164.99, 129.38 APE9-dihe-na -126.69, -126.94 APE8-dihe-in -91.63, 124.43 APE8-rot-in 299.73 APE67-dihe-in -58.25, -31.07 -56.39, -48.22 APE12-dist-in 10.8295 APE11-dist-in 11.4695 APE10-dist-out 9.5141 APE9-dist-in 4.0299 Q207D None None XRAY 1.59 0.219 0.261 B 301.0 279.0 16 32 23 9 [[207, 497]] 1.0 5s7u Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7U — TKL ACVR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name