PDB: 5S7T — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7TB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7TB Q04771 205 498 509.0 LU8:501,XGJ:505,XGJ:506,XGJ:507 Type1,Allosteric,Allosteric,Allosteric Inactive DFGin 7.3485 13.3837 BLAminus -130.84, 165.78 74.23, 86.23 -101.88, 22.54 301.68, 171.79 -65.62, -21.79 in-out in 8.8425 Saltbr-out 4.3703 HRD-in -75.87, -54.78 79.04, -1.82 out-in-out SNCoio in-out ActLoopNT-in 2.9373 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -106.86, 165.74 APE9-dihe-na -60.63, 163.96 APE8-dihe-in -61.22, 126.89 APE8-rot-in 299.34 APE67-dihe-in -62.98, -26.85 -63.53, -36.43 APE12-dist-in 10.5242 APE11-dist-out 6.9677 APE10-dist-out 9.1121 APE9-dist-in 3.8863 Q207D None None XRAY 1.3 0.155 0.174 B 301.0 294.0 0 32 32 0 [[207, 497]] 1.0 5s7t TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7TA Q04771 202 499 509.0 LU8:501,LU8:507,LU8:508,XGJ:509,XGJ:510,XGJ:511 Type1,Allosteric,Allosteric,Allosteric,Allosteric,Allosteric Inactive DFGin 8.3641 13.3581 BLAminus -122.53, 161.24 78.81, 92.17 -103.84, 26.27 299.68, 1.07 -70.27, -17.35 in-out in 9.1872 Saltbr-out 6.1023 HRD-in -73.55, -56.12 78.98, 0.06 out-in-out SNCoio in-out ActLoopNT-in 2.9448 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -126.64, 169.46 APE9-dihe-na -62.74, 163.72 APE8-dihe-in -63.21, 123.01 APE8-rot-in 300.97 APE67-dihe-in -58.38, -31.17 -61.88, -38.7 APE12-dist-none 999.0 APE11-dist-out 6.217 APE10-dist-out 8.8776 APE9-dist-in 3.7084 Q207D None None XRAY 1.3 0.155 0.174 A 301.0 284.0 14 32 20 12 [[207, 497]] 1.0 5s7t TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7T — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7TB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7TB Q04771 205 498 509.0 LU8:501,XGJ:505,XGJ:506,XGJ:507 Type1,Allosteric,Allosteric,Allosteric Inactive DFGin 7.3485 13.3837 BLAminus -130.84, 165.78 74.23, 86.23 -101.88, 22.54 301.68, 171.79 -65.62, -21.79 in-out in 8.8425 Saltbr-out 4.3703 HRD-in -75.87, -54.78 79.04, -1.82 out-in-out SNCoio in-out ActLoopNT-in 2.9373 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -106.86, 165.74 APE9-dihe-na -60.63, 163.96 APE8-dihe-in -61.22, 126.89 APE8-rot-in 299.34 APE67-dihe-in -62.98, -26.85 -63.53, -36.43 APE12-dist-in 10.5242 APE11-dist-out 6.9677 APE10-dist-out 9.1121 APE9-dist-in 3.8863 Q207D None None XRAY 1.3 0.155 0.174 B 301.0 294.0 0 32 32 0 [[207, 497]] 1.0 5s7t Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7TA Q04771 202 499 509.0 LU8:501,LU8:507,LU8:508,XGJ:509,XGJ:510,XGJ:511 Type1,Allosteric,Allosteric,Allosteric,Allosteric,Allosteric Inactive DFGin 8.3641 13.3581 BLAminus -122.53, 161.24 78.81, 92.17 -103.84, 26.27 299.68, 1.07 -70.27, -17.35 in-out in 9.1872 Saltbr-out 6.1023 HRD-in -73.55, -56.12 78.98, 0.06 out-in-out SNCoio in-out ActLoopNT-in 2.9448 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -126.64, 169.46 APE9-dihe-na -62.74, 163.72 APE8-dihe-in -63.21, 123.01 APE8-rot-in 300.97 APE67-dihe-in -58.38, -31.17 -61.88, -38.7 APE12-dist-none 999.0 APE11-dist-out 6.217 APE10-dist-out 8.8776 APE9-dist-in 3.7084 Q207D None None XRAY 1.3 0.155 0.174 A 301.0 284.0 14 32 20 12 [[207, 497]] 1.0 5s7t Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7T — TKL ACVR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name