PDB: 5S7S — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7SB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7SB Q04771 205 499 509.0 LU8:501,09V:505 Type1,Allosteric Inactive DFGin 6.9873 13.4064 BLAminus -127.22, 162.49 75.55, 89.77 -103.58, 21.52 302.17, 178.46 -71.16, -15.05 in-out in 8.8785 Saltbr-out 4.7655 HRD-in -78.6, -54.23 80.1, -1.5 out-in-out SNCoio in-out ActLoopNT-in 2.9249 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -118.31, 165.17 APE9-dihe-na -61.08, 163.96 APE8-dihe-in -59.96, 128.29 APE8-rot-in 298.36 APE67-dihe-in -59.32, -26.33 -61.06, -42.91 APE12-dist-in 10.2601 APE11-dist-out 6.1893 APE10-dist-out 9.0191 APE9-dist-in 3.7777 Q207D None None XRAY 1.3 0.153 0.171 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s7s TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7SA Q04771 202 499 509.0 LU8:501,LU8:508,LU8:509,09V:510 Type1,Allosteric,Allosteric,Allosteric Inactive DFGin 8.3742 13.2602 BLAminus -125.11, 163.99 74.48, 91.32 -103.07, 26.34 302.08, 178.93 -70.93, -18.68 in-out in 9.1341 Saltbr-out 5.9366 HRD-in -77.09, -53.7 75.14, 2.55 out-in-out SNCoio in-out ActLoopNT-in 2.9167 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -120.89, 171.8 APE9-dihe-na -59.35, 163.03 APE8-dihe-in -63.02, 122.62 APE8-rot-in 301.85 APE67-dihe-in -55.53, -31.77 -61.45, -39.86 APE12-dist-in 10.5844 APE11-dist-out 6.3931 APE10-dist-out 8.796 APE9-dist-in 3.663 Q207D None None XRAY 1.3 0.153 0.171 A 301.0 287.0 11 32 23 9 [[207, 497]] 1.0 5s7s TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7S — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7SB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7SB Q04771 205 499 509.0 LU8:501,09V:505 Type1,Allosteric Inactive DFGin 6.9873 13.4064 BLAminus -127.22, 162.49 75.55, 89.77 -103.58, 21.52 302.17, 178.46 -71.16, -15.05 in-out in 8.8785 Saltbr-out 4.7655 HRD-in -78.6, -54.23 80.1, -1.5 out-in-out SNCoio in-out ActLoopNT-in 2.9249 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -118.31, 165.17 APE9-dihe-na -61.08, 163.96 APE8-dihe-in -59.96, 128.29 APE8-rot-in 298.36 APE67-dihe-in -59.32, -26.33 -61.06, -42.91 APE12-dist-in 10.2601 APE11-dist-out 6.1893 APE10-dist-out 9.0191 APE9-dist-in 3.7777 Q207D None None XRAY 1.3 0.153 0.171 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s7s Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7SA Q04771 202 499 509.0 LU8:501,LU8:508,LU8:509,09V:510 Type1,Allosteric,Allosteric,Allosteric Inactive DFGin 8.3742 13.2602 BLAminus -125.11, 163.99 74.48, 91.32 -103.07, 26.34 302.08, 178.93 -70.93, -18.68 in-out in 9.1341 Saltbr-out 5.9366 HRD-in -77.09, -53.7 75.14, 2.55 out-in-out SNCoio in-out ActLoopNT-in 2.9167 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -120.89, 171.8 APE9-dihe-na -59.35, 163.03 APE8-dihe-in -63.02, 122.62 APE8-rot-in 301.85 APE67-dihe-in -55.53, -31.77 -61.45, -39.86 APE12-dist-in 10.5844 APE11-dist-out 6.3931 APE10-dist-out 8.796 APE9-dist-in 3.663 Q207D None None XRAY 1.3 0.153 0.171 A 301.0 287.0 11 32 23 9 [[207, 497]] 1.0 5s7s Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7S — TKL ACVR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name