PDB: 5S7Q — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7QB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7QB Q04771 205 499 509.0 XJM:1801,LU8:1802,XJM:1806 Allosteric,Type1,Allosteric Inactive DFGin 7.0354 13.341 BLAminus -124.49, 160.57 78.3, 88.59 -102.07, 16.77 299.19, 176.61 -55.48, -25.66 in-out in 8.6067 Saltbr-out 4.5008 HRD-in -84.23, -49.81 75.94, -2.06 out-in-out SNCoio in-out ActLoopNT-in 2.8845 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -124.81, 167.47 APE9-dihe-na -59.06, 164.28 APE8-dihe-in -59.12, 123.47 APE8-rot-in 303.32 APE67-dihe-in -63.13, -25.62 -55.86, -41.03 APE12-dist-in 10.2953 APE11-dist-out 6.5068 APE10-dist-out 8.8401 APE9-dist-in 3.7438 Q207D None None XRAY 1.53 0.209 0.243 B 301.0 291.0 4 32 32 0 [[207, 497]] 1.0 5s7q TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7QA Q04771 202 499 509.0 LU8:501,LU8:507,LU8:508 Type1,Allosteric,Allosteric Inactive DFGin 8.3905 13.1124 BLAminus -122.32, 165.01 69.61, 90.09 -98.74, 20.54 300.47, 4.84 -55.87, -28.73 in-out in 9.1154 Saltbr-out 6.1758 HRD-in -80.49, -54.34 80.36, -1.4 out-in-out SNCoio in-out ActLoopNT-in 2.9335 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -123.26, 178.66 APE9-dihe-na -63.48, 166.31 APE8-dihe-in -61.68, 126.19 APE8-rot-in 310.31 APE67-dihe-in -52.14, -34.66 -61.41, -42.72 APE12-dist-none 999.0 APE11-dist-out 6.7892 APE10-dist-out 8.8904 APE9-dist-in 3.5385 Q207D None None XRAY 1.53 0.209 0.243 A 301.0 282.0 16 32 19 13 [[207, 497]] 1.0 5s7q TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7Q — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7QB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7QB Q04771 205 499 509.0 XJM:1801,LU8:1802,XJM:1806 Allosteric,Type1,Allosteric Inactive DFGin 7.0354 13.341 BLAminus -124.49, 160.57 78.3, 88.59 -102.07, 16.77 299.19, 176.61 -55.48, -25.66 in-out in 8.6067 Saltbr-out 4.5008 HRD-in -84.23, -49.81 75.94, -2.06 out-in-out SNCoio in-out ActLoopNT-in 2.8845 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -124.81, 167.47 APE9-dihe-na -59.06, 164.28 APE8-dihe-in -59.12, 123.47 APE8-rot-in 303.32 APE67-dihe-in -63.13, -25.62 -55.86, -41.03 APE12-dist-in 10.2953 APE11-dist-out 6.5068 APE10-dist-out 8.8401 APE9-dist-in 3.7438 Q207D None None XRAY 1.53 0.209 0.243 B 301.0 291.0 4 32 32 0 [[207, 497]] 1.0 5s7q Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7QA Q04771 202 499 509.0 LU8:501,LU8:507,LU8:508 Type1,Allosteric,Allosteric Inactive DFGin 8.3905 13.1124 BLAminus -122.32, 165.01 69.61, 90.09 -98.74, 20.54 300.47, 4.84 -55.87, -28.73 in-out in 9.1154 Saltbr-out 6.1758 HRD-in -80.49, -54.34 80.36, -1.4 out-in-out SNCoio in-out ActLoopNT-in 2.9335 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -123.26, 178.66 APE9-dihe-na -63.48, 166.31 APE8-dihe-in -61.68, 126.19 APE8-rot-in 310.31 APE67-dihe-in -52.14, -34.66 -61.41, -42.72 APE12-dist-none 999.0 APE11-dist-out 6.7892 APE10-dist-out 8.8904 APE9-dist-in 3.5385 Q207D None None XRAY 1.53 0.209 0.243 A 301.0 282.0 16 32 19 13 [[207, 497]] 1.0 5s7q Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7Q — TKL ACVR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name