PDB: 5S7P — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7PB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7PB Q04771 208 499 509.0 LU8:501 Type1 Inactive DFGin 7.041 13.4201 BLAminus -127.32, 160.61 79.2, 88.36 -101.38, 20.66 301.74, 174.56 -69.08, -14.59 in-out in 8.8375 Saltbr-out 4.7494 HRD-in -79.58, -51.94 76.5, -1.66 out-in-out SNCoio in-out ActLoopNT-in 2.9461 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -122.23, 166.15 APE9-dihe-na -60.81, 164.72 APE8-dihe-in -59.48, 128.85 APE8-rot-in 300.38 APE67-dihe-in -62.62, -25.57 -64.98, -36.96 APE12-dist-in 10.458 APE11-dist-out 6.1919 APE10-dist-out 8.9709 APE9-dist-in 3.8702 Q207D None None XRAY 1.31 0.158 0.176 B 301.0 289.0 3 32 32 0 [[207, 497]] 1.0 5s7p TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7PA Q04771 202 499 509.0 LU8:501,LU8:507,LU8:508,V1L:509 Type1,Allosteric,Allosteric,Allosteric Inactive DFGin 8.3631 13.3516 BLAminus -121.35, 161.97 76.5, 90.18 -103.45, 27.08 300.94, 178.65 -69.09, -20.15 in-out in 9.1735 Saltbr-out 6.1815 HRD-in -76.2, -55.65 77.56, 1.63 out-in-out SNCoio in-out ActLoopNT-in 2.934 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -124.42, 170.99 APE9-dihe-na -65.1, 166.64 APE8-dihe-in -64.52, 122.28 APE8-rot-in 301.0 APE67-dihe-in -57.28, -33.44 -60.97, -37.49 APE12-dist-none 999.0 APE11-dist-out 6.3362 APE10-dist-out 8.8101 APE9-dist-in 3.6483 Q207D None None XRAY 1.31 0.158 0.176 A 301.0 283.0 15 32 19 13 [[207, 497]] 1.0 5s7p TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7P — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7PB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7PB Q04771 208 499 509.0 LU8:501 Type1 Inactive DFGin 7.041 13.4201 BLAminus -127.32, 160.61 79.2, 88.36 -101.38, 20.66 301.74, 174.56 -69.08, -14.59 in-out in 8.8375 Saltbr-out 4.7494 HRD-in -79.58, -51.94 76.5, -1.66 out-in-out SNCoio in-out ActLoopNT-in 2.9461 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -122.23, 166.15 APE9-dihe-na -60.81, 164.72 APE8-dihe-in -59.48, 128.85 APE8-rot-in 300.38 APE67-dihe-in -62.62, -25.57 -64.98, -36.96 APE12-dist-in 10.458 APE11-dist-out 6.1919 APE10-dist-out 8.9709 APE9-dist-in 3.8702 Q207D None None XRAY 1.31 0.158 0.176 B 301.0 289.0 3 32 32 0 [[207, 497]] 1.0 5s7p Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7PA Q04771 202 499 509.0 LU8:501,LU8:507,LU8:508,V1L:509 Type1,Allosteric,Allosteric,Allosteric Inactive DFGin 8.3631 13.3516 BLAminus -121.35, 161.97 76.5, 90.18 -103.45, 27.08 300.94, 178.65 -69.09, -20.15 in-out in 9.1735 Saltbr-out 6.1815 HRD-in -76.2, -55.65 77.56, 1.63 out-in-out SNCoio in-out ActLoopNT-in 2.934 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -124.42, 170.99 APE9-dihe-na -65.1, 166.64 APE8-dihe-in -64.52, 122.28 APE8-rot-in 301.0 APE67-dihe-in -57.28, -33.44 -60.97, -37.49 APE12-dist-none 999.0 APE11-dist-out 6.3362 APE10-dist-out 8.8101 APE9-dist-in 3.6483 Q207D None None XRAY 1.31 0.158 0.176 A 301.0 283.0 15 32 19 13 [[207, 497]] 1.0 5s7p Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7P — TKL ACVR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name