PDB: 5S7K — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7KB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7KB Q04771 205 499 509.0 LU8:501,XEJ:504 Type1,Allosteric Inactive DFGin 6.9806 13.2701 BLAminus -124.3, 164.86 75.9, 87.47 -102.78, 21.12 305.49, 0.35 -65.97, -18.91 in-out in 8.8339 Saltbr-out 4.6466 HRD-in -79.74, -53.13 79.6, -2.25 out-in-out SNCoio in-out ActLoopNT-in 2.8589 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -122.28, 163.22 APE9-dihe-na -60.14, 169.9 APE8-dihe-in -64.39, 127.18 APE8-rot-in 298.46 APE67-dihe-in -57.76, -29.28 -59.11, -42.6 APE12-dist-in 10.4215 APE11-dist-out 6.3009 APE10-dist-out 8.9738 APE9-dist-in 3.6767 None None None XRAY 1.31 0.162 0.188 B 301.0 293.0 2 32 32 0 [[207, 497]] 1.0 5s7k TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7KA Q04771 202 499 509.0 LU8:501,LU8:506,LU8:507,XEJ:508 Type1,Allosteric,Allosteric,Allosteric Inactive DFGin 8.3571 13.2978 BLAminus -121.51, 161.1 74.44, 89.19 -99.73, 25.08 301.6, 0.3 -69.43, -16.12 in-out in 9.3172 Saltbr-out 6.0158 HRD-in -77.56, -55.15 80.71, -0.51 out-in-none SNCoin in-none ActLoopNT-in 2.9289 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_niii APE10-dihe-na -93.42, -15.71 APE9-dihe-na -77.62, 169.4 APE8-dihe-in -59.03, 123.75 APE8-rot-in 304.14 APE67-dihe-in -58.63, -30.05 -60.7, -39.73 APE12-dist-none 999.0 APE11-dist-in 11.7963 APE10-dist-in 6.0089 APE9-dist-in 3.542 None None None XRAY 1.31 0.162 0.188 A 301.0 285.0 13 32 21 11 [[207, 497]] 1.0 5s7k TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7K — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7KB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7KB Q04771 205 499 509.0 LU8:501,XEJ:504 Type1,Allosteric Inactive DFGin 6.9806 13.2701 BLAminus -124.3, 164.86 75.9, 87.47 -102.78, 21.12 305.49, 0.35 -65.97, -18.91 in-out in 8.8339 Saltbr-out 4.6466 HRD-in -79.74, -53.13 79.6, -2.25 out-in-out SNCoio in-out ActLoopNT-in 2.8589 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -122.28, 163.22 APE9-dihe-na -60.14, 169.9 APE8-dihe-in -64.39, 127.18 APE8-rot-in 298.46 APE67-dihe-in -57.76, -29.28 -59.11, -42.6 APE12-dist-in 10.4215 APE11-dist-out 6.3009 APE10-dist-out 8.9738 APE9-dist-in 3.6767 None None None XRAY 1.31 0.162 0.188 B 301.0 293.0 2 32 32 0 [[207, 497]] 1.0 5s7k Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7KA Q04771 202 499 509.0 LU8:501,LU8:506,LU8:507,XEJ:508 Type1,Allosteric,Allosteric,Allosteric Inactive DFGin 8.3571 13.2978 BLAminus -121.51, 161.1 74.44, 89.19 -99.73, 25.08 301.6, 0.3 -69.43, -16.12 in-out in 9.3172 Saltbr-out 6.0158 HRD-in -77.56, -55.15 80.71, -0.51 out-in-none SNCoin in-none ActLoopNT-in 2.9289 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_niii APE10-dihe-na -93.42, -15.71 APE9-dihe-na -77.62, 169.4 APE8-dihe-in -59.03, 123.75 APE8-rot-in 304.14 APE67-dihe-in -58.63, -30.05 -60.7, -39.73 APE12-dist-none 999.0 APE11-dist-in 11.7963 APE10-dist-in 6.0089 APE9-dist-in 3.542 None None None XRAY 1.31 0.162 0.188 A 301.0 285.0 13 32 21 11 [[207, 497]] 1.0 5s7k Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7K — TKL ACVR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name