PDB: 5S7I — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7IB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7IA Q04771 201 499 509.0 LU8:501,LU8:507,LU8:508,HV2:509,HV2:510,HV2:511 Type1,Allosteric,Allosteric,Allosteric,Allosteric,Allosteric Inactive DFGin 8.4231 13.4136 BLAminus -121.19, 161.49 77.75, 90.77 -102.55, 26.67 296.81, 175.99 -70.08, -16.54 in-out in 9.1542 Saltbr-out 6.1975 HRD-in -79.1, -52.38 76.17, 1.2 out-in-out SNCoio in-out ActLoopNT-in 2.8872 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -123.34, 168.68 APE9-dihe-na -65.41, 166.87 APE8-dihe-in -63.35, 124.96 APE8-rot-in 301.24 APE67-dihe-in -56.97, -30.73 -63.49, -38.5 APE12-dist-none 999.0 APE11-dist-out 6.0485 APE10-dist-out 8.8992 APE9-dist-in 3.6905 Q207D None None XRAY 1.3 0.158 0.176 A 301.0 284.0 15 32 19 13 [[207, 497]] 1.0 5s7i TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7IB Q04771 205 499 509.0 LU8:501,HV2:505,HV2:506,HV2:507,HV2:508,HV2:509,HV2:510,HV2:511,HV2:512,HV2:513 Type1,Allosteric,Allosteric,Allosteric,Allosteric,Allosteric,Allosteric,Allosteric,Allosteric,Allosteric Inactive DFGin 7.0297 13.3467 BLAminus -124.03, 163.17 76.81, 90.06 -103.28, 20.27 301.31, 176.76 -69.97, -14.64 in-out in 8.7537 Saltbr-out 4.763 HRD-in -75.19, -55.72 81.55, -2.41 out-in-out SNCoio in-out ActLoopNT-in 2.9502 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -121.42, 164.49 APE9-dihe-na -59.34, 164.13 APE8-dihe-in -60.56, 130.0 APE8-rot-in 297.57 APE67-dihe-in -61.93, -26.2 -62.79, -39.84 APE12-dist-in 10.3438 APE11-dist-out 6.121 APE10-dist-out 9.0233 APE9-dist-in 3.8528 Q207D None None XRAY 1.3 0.158 0.176 B 301.0 294.0 1 32 32 0 [[207, 497]] 1.0 5s7i TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7I — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7IB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7IA Q04771 201 499 509.0 LU8:501,LU8:507,LU8:508,HV2:509,HV2:510,HV2:511 Type1,Allosteric,Allosteric,Allosteric,Allosteric,Allosteric Inactive DFGin 8.4231 13.4136 BLAminus -121.19, 161.49 77.75, 90.77 -102.55, 26.67 296.81, 175.99 -70.08, -16.54 in-out in 9.1542 Saltbr-out 6.1975 HRD-in -79.1, -52.38 76.17, 1.2 out-in-out SNCoio in-out ActLoopNT-in 2.8872 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -123.34, 168.68 APE9-dihe-na -65.41, 166.87 APE8-dihe-in -63.35, 124.96 APE8-rot-in 301.24 APE67-dihe-in -56.97, -30.73 -63.49, -38.5 APE12-dist-none 999.0 APE11-dist-out 6.0485 APE10-dist-out 8.8992 APE9-dist-in 3.6905 Q207D None None XRAY 1.3 0.158 0.176 A 301.0 284.0 15 32 19 13 [[207, 497]] 1.0 5s7i Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7IB Q04771 205 499 509.0 LU8:501,HV2:505,HV2:506,HV2:507,HV2:508,HV2:509,HV2:510,HV2:511,HV2:512,HV2:513 Type1,Allosteric,Allosteric,Allosteric,Allosteric,Allosteric,Allosteric,Allosteric,Allosteric,Allosteric Inactive DFGin 7.0297 13.3467 BLAminus -124.03, 163.17 76.81, 90.06 -103.28, 20.27 301.31, 176.76 -69.97, -14.64 in-out in 8.7537 Saltbr-out 4.763 HRD-in -75.19, -55.72 81.55, -2.41 out-in-out SNCoio in-out ActLoopNT-in 2.9502 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -121.42, 164.49 APE9-dihe-na -59.34, 164.13 APE8-dihe-in -60.56, 130.0 APE8-rot-in 297.57 APE67-dihe-in -61.93, -26.2 -62.79, -39.84 APE12-dist-in 10.3438 APE11-dist-out 6.121 APE10-dist-out 9.0233 APE9-dist-in 3.8528 Q207D None None XRAY 1.3 0.158 0.176 B 301.0 294.0 1 32 32 0 [[207, 497]] 1.0 5s7i Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7I — TKL ACVR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name