PDB: 5S7H — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7HB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7HB Q04771 205 499 509.0 LU8:501 Type1 Inactive DFGin 7.002 13.3868 BLAminus -126.96, 163.26 76.81, 86.99 -100.87, 23.04 301.4, 176.52 -72.34, -14.12 in-out in 8.8346 Saltbr-out 4.7589 HRD-in -77.49, -53.08 77.02, -2.86 out-in-out SNCoio in-out ActLoopNT-in 2.9428 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -120.19, 165.21 APE9-dihe-na -62.02, 164.93 APE8-dihe-in -59.21, 129.08 APE8-rot-in 298.47 APE67-dihe-in -58.12, -30.1 -64.15, -39.55 APE12-dist-in 10.3133 APE11-dist-out 6.1622 APE10-dist-out 9.011 APE9-dist-in 3.7279 Q207D None None XRAY 1.3 0.158 0.18 B 301.0 293.0 2 32 32 0 [[207, 497]] 1.0 5s7h TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7HA Q04771 201 499 509.0 LU8:501,LU8:507,LU8:508,HVB:509,HVB:510 Type1,Allosteric,Allosteric,Allosteric,Allosteric Inactive DFGin 8.4004 13.3492 BLAminus -122.03, 161.2 75.68, 88.77 -99.68, 25.56 301.4, 178.71 -69.41, -15.19 in-out in 9.2841 Saltbr-out 6.1124 HRD-in -74.82, -53.78 79.5, -0.11 out-in-out SNCoio in-out ActLoopNT-in 2.9554 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -124.66, 158.62 APE9-dihe-na -71.55, -178.8 APE8-dihe-in -67.44, 125.65 APE8-rot-in 300.35 APE67-dihe-in -57.2, -30.23 -61.33, -40.16 APE12-dist-none 999.0 APE11-dist-out 6.4173 APE10-dist-out 9.333 APE9-dist-in 3.6164 Q207D None None XRAY 1.3 0.158 0.18 A 301.0 284.0 15 32 20 12 [[207, 497]] 1.0 5s7h TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7H — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7HB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7HB Q04771 205 499 509.0 LU8:501 Type1 Inactive DFGin 7.002 13.3868 BLAminus -126.96, 163.26 76.81, 86.99 -100.87, 23.04 301.4, 176.52 -72.34, -14.12 in-out in 8.8346 Saltbr-out 4.7589 HRD-in -77.49, -53.08 77.02, -2.86 out-in-out SNCoio in-out ActLoopNT-in 2.9428 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -120.19, 165.21 APE9-dihe-na -62.02, 164.93 APE8-dihe-in -59.21, 129.08 APE8-rot-in 298.47 APE67-dihe-in -58.12, -30.1 -64.15, -39.55 APE12-dist-in 10.3133 APE11-dist-out 6.1622 APE10-dist-out 9.011 APE9-dist-in 3.7279 Q207D None None XRAY 1.3 0.158 0.18 B 301.0 293.0 2 32 32 0 [[207, 497]] 1.0 5s7h Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7HA Q04771 201 499 509.0 LU8:501,LU8:507,LU8:508,HVB:509,HVB:510 Type1,Allosteric,Allosteric,Allosteric,Allosteric Inactive DFGin 8.4004 13.3492 BLAminus -122.03, 161.2 75.68, 88.77 -99.68, 25.56 301.4, 178.71 -69.41, -15.19 in-out in 9.2841 Saltbr-out 6.1124 HRD-in -74.82, -53.78 79.5, -0.11 out-in-out SNCoio in-out ActLoopNT-in 2.9554 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -124.66, 158.62 APE9-dihe-na -71.55, -178.8 APE8-dihe-in -67.44, 125.65 APE8-rot-in 300.35 APE67-dihe-in -57.2, -30.23 -61.33, -40.16 APE12-dist-none 999.0 APE11-dist-out 6.4173 APE10-dist-out 9.333 APE9-dist-in 3.6164 Q207D None None XRAY 1.3 0.158 0.18 A 301.0 284.0 15 32 20 12 [[207, 497]] 1.0 5s7h Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7H — TKL ACVR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name