PDB: 5S7G — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7GB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7GB Q04771 207 499 509.0 LU8:501 Type1 Inactive DFGin 6.6407 13.4949 BLAminus -119.72, 159.88 82.75, 87.21 -98.63, 18.92 305.17, 0.99 -67.48, -19.33 in-out in 9.0173 Saltbr-out 4.9584 HRD-in -77.01, -50.93 75.96, 1.34 out-in-none SNCoin in-none ActLoopNT-in 2.9658 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_niii APE10-dihe-na -89.52, 148.19 APE9-dihe-na 117.39, 161.66 APE8-dihe-in -69.4, 128.02 APE8-rot-in 308.42 APE67-dihe-in -59.26, -33.51 -60.94, -38.65 APE12-dist-none 999.0 APE11-dist-in 11.6619 APE10-dist-in 5.8166 APE9-dist-in 3.9424 Q207D None None XRAY 1.78 0.206 0.252 B 301.0 281.0 12 32 24 8 [[207, 497]] 1.0 5s7g TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7GA Q04771 202 498 509.0 LU8:501,LU8:507,LU8:508 Type1,Allosteric,Allosteric Inactive DFGin 8.4994 13.3287 BLAminus -125.16, 165.77 74.59, 86.92 -99.45, 20.56 296.92, 176.9 -55.21, -25.24 in-out in 9.3288 Saltbr-out 5.7883 HRD-in -78.53, -53.51 74.34, 2.0 out-in-none SNCoin in-none ActLoopNT-in 2.9022 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_niii APE10-dihe-na -116.42, 161.19 APE9-dihe-na 107.2, -168.38 APE8-dihe-in -91.58, 123.63 APE8-rot-in 309.25 APE67-dihe-in -59.99, -30.06 -55.11, -41.51 APE12-dist-none 999.0 APE11-dist-in 10.3661 APE10-dist-in 6.4234 APE9-dist-in 3.9062 Q207D None None XRAY 1.78 0.206 0.252 A 301.0 284.0 13 32 19 13 [[207, 497]] 1.0 5s7g TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7G — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7GB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7GB Q04771 207 499 509.0 LU8:501 Type1 Inactive DFGin 6.6407 13.4949 BLAminus -119.72, 159.88 82.75, 87.21 -98.63, 18.92 305.17, 0.99 -67.48, -19.33 in-out in 9.0173 Saltbr-out 4.9584 HRD-in -77.01, -50.93 75.96, 1.34 out-in-none SNCoin in-none ActLoopNT-in 2.9658 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_niii APE10-dihe-na -89.52, 148.19 APE9-dihe-na 117.39, 161.66 APE8-dihe-in -69.4, 128.02 APE8-rot-in 308.42 APE67-dihe-in -59.26, -33.51 -60.94, -38.65 APE12-dist-none 999.0 APE11-dist-in 11.6619 APE10-dist-in 5.8166 APE9-dist-in 3.9424 Q207D None None XRAY 1.78 0.206 0.252 B 301.0 281.0 12 32 24 8 [[207, 497]] 1.0 5s7g Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7GA Q04771 202 498 509.0 LU8:501,LU8:507,LU8:508 Type1,Allosteric,Allosteric Inactive DFGin 8.4994 13.3287 BLAminus -125.16, 165.77 74.59, 86.92 -99.45, 20.56 296.92, 176.9 -55.21, -25.24 in-out in 9.3288 Saltbr-out 5.7883 HRD-in -78.53, -53.51 74.34, 2.0 out-in-none SNCoin in-none ActLoopNT-in 2.9022 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_niii APE10-dihe-na -116.42, 161.19 APE9-dihe-na 107.2, -168.38 APE8-dihe-in -91.58, 123.63 APE8-rot-in 309.25 APE67-dihe-in -59.99, -30.06 -55.11, -41.51 APE12-dist-none 999.0 APE11-dist-in 10.3661 APE10-dist-in 6.4234 APE9-dist-in 3.9062 Q207D None None XRAY 1.78 0.206 0.252 A 301.0 284.0 13 32 19 13 [[207, 497]] 1.0 5s7g Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7G — TKL ACVR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name