PDB: 5S7F — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7FB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7FA Q04771 202 499 509.0 LU8:501,LU8:508,LU8:509 Type1,Allosteric,Allosteric Inactive DFGin 8.3693 13.3205 BLAminus -122.11, 160.49 78.65, 89.18 -101.96, 26.72 301.12, 175.97 -69.09, -20.41 in-out in 9.1008 Saltbr-out 6.107 HRD-in -78.16, -52.77 77.11, -0.2 out-in-out SNCoio in-out ActLoopNT-in 2.9175 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -124.41, 172.12 APE9-dihe-na -64.48, 163.27 APE8-dihe-in -60.82, 122.78 APE8-rot-in 304.26 APE67-dihe-in -57.8, -32.72 -63.43, -34.75 APE12-dist-none 999.0 APE11-dist-out 6.2328 APE10-dist-out 8.8508 APE9-dist-in 3.6754 Q207D None None XRAY 1.31 0.151 0.169 A 301.0 283.0 15 32 19 13 [[207, 497]] 1.0 5s7f TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7FB Q04771 205 499 509.0 LU8:501,XH4:505,XH4:506 Type1,Allosteric,Allosteric Inactive DFGin 7.0038 13.3859 BLAminus -125.15, 160.98 75.58, 90.9 -103.26, 20.62 302.27, 174.02 -66.35, -18.49 in-out in 8.851 Saltbr-out 4.7675 HRD-in -78.67, -52.91 79.11, -3.95 out-in-out SNCoio in-out ActLoopNT-in 2.9186 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -121.71, 164.43 APE9-dihe-na -63.66, 165.2 APE8-dihe-in -60.32, 128.18 APE8-rot-in 298.19 APE67-dihe-in -60.19, -25.76 -61.92, -39.78 APE12-dist-in 10.3447 APE11-dist-out 6.1141 APE10-dist-out 9.0418 APE9-dist-in 3.8278 Q207D None None XRAY 1.31 0.151 0.169 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s7f TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7F — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7FB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7FA Q04771 202 499 509.0 LU8:501,LU8:508,LU8:509 Type1,Allosteric,Allosteric Inactive DFGin 8.3693 13.3205 BLAminus -122.11, 160.49 78.65, 89.18 -101.96, 26.72 301.12, 175.97 -69.09, -20.41 in-out in 9.1008 Saltbr-out 6.107 HRD-in -78.16, -52.77 77.11, -0.2 out-in-out SNCoio in-out ActLoopNT-in 2.9175 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -124.41, 172.12 APE9-dihe-na -64.48, 163.27 APE8-dihe-in -60.82, 122.78 APE8-rot-in 304.26 APE67-dihe-in -57.8, -32.72 -63.43, -34.75 APE12-dist-none 999.0 APE11-dist-out 6.2328 APE10-dist-out 8.8508 APE9-dist-in 3.6754 Q207D None None XRAY 1.31 0.151 0.169 A 301.0 283.0 15 32 19 13 [[207, 497]] 1.0 5s7f Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7FB Q04771 205 499 509.0 LU8:501,XH4:505,XH4:506 Type1,Allosteric,Allosteric Inactive DFGin 7.0038 13.3859 BLAminus -125.15, 160.98 75.58, 90.9 -103.26, 20.62 302.27, 174.02 -66.35, -18.49 in-out in 8.851 Saltbr-out 4.7675 HRD-in -78.67, -52.91 79.11, -3.95 out-in-out SNCoio in-out ActLoopNT-in 2.9186 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -121.71, 164.43 APE9-dihe-na -63.66, 165.2 APE8-dihe-in -60.32, 128.18 APE8-rot-in 298.19 APE67-dihe-in -60.19, -25.76 -61.92, -39.78 APE12-dist-in 10.3447 APE11-dist-out 6.1141 APE10-dist-out 9.0418 APE9-dist-in 3.8278 Q207D None None XRAY 1.31 0.151 0.169 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s7f Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7F — TKL ACVR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name