PDB: 5S7B — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7BB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7BB Q04771 205 499 509.0 LU8:501,XH7:506 Type1,Allosteric Inactive DFGin 7.0215 13.362 BLAminus -121.46, 161.83 78.44, 88.34 -102.47, 19.49 301.42, 173.88 -65.45, -20.59 in-out in 8.7895 Saltbr-out 4.6853 HRD-in -74.99, -55.16 78.67, -0.58 out-in-out SNCoio in-out ActLoopNT-in 2.9128 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -119.52, 156.89 APE9-dihe-na -51.95, 170.55 APE8-dihe-in -69.31, 128.28 APE8-rot-in 299.94 APE67-dihe-in -63.25, -25.99 -60.99, -39.27 APE12-dist-in 10.4037 APE11-dist-out 6.3927 APE10-dist-out 9.0949 APE9-dist-in 3.8072 Q207D None None XRAY 1.32 0.169 0.195 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s7b TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7BA Q04771 202 499 509.0 LU8:501,LU8:507,LU8:508,XH7:509,XH7:510 Type1,Allosteric,Allosteric,Allosteric,Allosteric Inactive DFGin 8.4061 13.3525 BLAminus -122.54, 161.25 77.75, 89.14 -102.53, 25.49 298.26, 177.49 -68.5, -17.41 in-out in 9.1558 Saltbr-out 5.9622 HRD-in -75.98, -54.72 78.12, -0.13 out-in-out SNCoio in-out ActLoopNT-in 2.9081 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oioi APE10-dihe-na -121.74, 156.48 APE9-dihe-na -76.58, -177.16 APE8-dihe-in -62.22, 124.84 APE8-rot-in 304.94 APE67-dihe-in -57.93, -31.87 -59.46, -41.19 APE12-dist-out 5.2863 APE11-dist-in 8.586 APE10-dist-out 9.3111 APE9-dist-in 3.6782 Q207D None None XRAY 1.32 0.169 0.195 A 301.0 285.0 13 32 22 10 [[207, 497]] 1.0 5s7b TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7B — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7BB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7BB Q04771 205 499 509.0 LU8:501,XH7:506 Type1,Allosteric Inactive DFGin 7.0215 13.362 BLAminus -121.46, 161.83 78.44, 88.34 -102.47, 19.49 301.42, 173.88 -65.45, -20.59 in-out in 8.7895 Saltbr-out 4.6853 HRD-in -74.99, -55.16 78.67, -0.58 out-in-out SNCoio in-out ActLoopNT-in 2.9128 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -119.52, 156.89 APE9-dihe-na -51.95, 170.55 APE8-dihe-in -69.31, 128.28 APE8-rot-in 299.94 APE67-dihe-in -63.25, -25.99 -60.99, -39.27 APE12-dist-in 10.4037 APE11-dist-out 6.3927 APE10-dist-out 9.0949 APE9-dist-in 3.8072 Q207D None None XRAY 1.32 0.169 0.195 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s7b Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7BA Q04771 202 499 509.0 LU8:501,LU8:507,LU8:508,XH7:509,XH7:510 Type1,Allosteric,Allosteric,Allosteric,Allosteric Inactive DFGin 8.4061 13.3525 BLAminus -122.54, 161.25 77.75, 89.14 -102.53, 25.49 298.26, 177.49 -68.5, -17.41 in-out in 9.1558 Saltbr-out 5.9622 HRD-in -75.98, -54.72 78.12, -0.13 out-in-out SNCoio in-out ActLoopNT-in 2.9081 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oioi APE10-dihe-na -121.74, 156.48 APE9-dihe-na -76.58, -177.16 APE8-dihe-in -62.22, 124.84 APE8-rot-in 304.94 APE67-dihe-in -57.93, -31.87 -59.46, -41.19 APE12-dist-out 5.2863 APE11-dist-in 8.586 APE10-dist-out 9.3111 APE9-dist-in 3.6782 Q207D None None XRAY 1.32 0.169 0.195 A 301.0 285.0 13 32 22 10 [[207, 497]] 1.0 5s7b Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7B — TKL ACVR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name